| Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ... Nature 468 (7320), 98-102, 2010 | 646 | 2010 |
| A dual role for autophagy in a murine model of lung cancer S Rao, L Tortola, T Perlot, G Wirnsberger, M Novatchkova, R Nitsch, ... Nature communications 5 (1), 3056, 2014 | 444 | 2014 |
| Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate JA Pospisilik, D Schramek, H Schnidar, SJF Cronin, NT Nehme, X Zhang, ... Cell 140 (1), 148-160, 2010 | 420 | 2010 |
| Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection SJF Cronin, NT Nehme, S Limmer, S Liegeois, JA Pospisilik, D Schramek, ... Science 325 (5938), 340-343, 2009 | 364 | 2009 |
| A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene GG Neely, A Hess, M Costigan, AC Keene, S Goulas, M Langeslag, ... Cell 143 (4), 628-638, 2010 | 351 | 2010 |
| Translation from unconventional 5′ start sites drives tumour initiation A Sendoel, JG Dunn, EH Rodriguez, S Naik, NC Gomez, B Hurwitz, ... Nature 541 (7638), 494-499, 2017 | 313 | 2017 |
| Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas D Schramek, A Sendoel, JP Segal, S Beronja, E Heller, D Oristian, ... Science 343 (6168), 309-313, 2014 | 309 | 2014 |
| Forward and reverse genetics through derivation of haploid mouse embryonic stem cells U Elling, J Taubenschmid, G Wirnsberger, R O'Malley, SP Demers, ... Cell stem cell 9 (6), 563-574, 2011 | 283 | 2011 |
| Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ... Nature genetics 50 (12), 1650-1657, 2018 | 194 | 2018 |
| Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ... Nature communications 11 (1), 3701, 2020 | 165 | 2020 |
| RANKL/RANK control Brca1 mutation-driven mammary tumors V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ... Cell research 26 (7), 761-774, 2016 | 164 | 2016 |
| Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling SK Loganathan, K Schleicher, A Malik, R Quevedo, E Langille, K Teng, ... Science 367 (6483), 1264-1269, 2020 | 161 | 2020 |
| Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis B Grabner, D Schramek, KM Mueller, HP Moll, J Svinka, T Hoffmann, ... Nature communications 6 (1), 6285, 2015 | 159 | 2015 |
| RANKL/RANK—beyond bones R Hanada, T Hanada, V Sigl, D Schramek, JM Penninger Journal of Molecular Medicine 89, 647-656, 2011 | 159 | 2011 |
| Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein T Brummer, D Schramek, VM Hayes, HL Bennett, CE Caldon, ... Journal of Biological Chemistry 281 (1), 626-637, 2006 | 145 | 2006 |
| Afatinib restrains K-RAS–driven lung tumorigenesis HP Moll, K Pranz, M Musteanu, B Grabner, N Hruschka, J Mohrherr, ... Science translational medicine 10 (446), eaao2301, 2018 | 125 | 2018 |
| Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ... Development 140 (7), 1397-1401, 2013 | 118 | 2013 |
| The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression D Schramek, A Kotsinas, A Meixner, T Wada, U Elling, JA Pospisilik, ... Nature genetics 43 (3), 212-219, 2011 | 117 | 2011 |
| Binary pan-cancer classes with distinct vulnerabilities defined by pro-or anti-cancer YAP/TEAD activity JD Pearson, K Huang, M Pacal, SR McCurdy, S Lu, A Aubry, T Yu, ... Cancer Cell 39 (8), 1115-1134. e12, 2021 | 115 | 2021 |
| CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens G Michlits, M Hubmann, SH Wu, G Vainorius, E Budusan, S Zhuk, ... Nature methods 14 (12), 1191-1197, 2017 | 110 | 2017 |
