Ahmet Bakan
Ahmet Bakan
Software Engineer at Google
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Cited by
Cited by
ProDy: Protein Dynamics Inferred from Theory and Experiments
A Bakan, LM Meireles, I Bahar
Bioinformatics 27 (11), 1575-1577, 2011
Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins
I Bahar, TR Lezon, A Bakan, IH Shrivastava
Chemical reviews 110 (3), 1463-1497, 2010
The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding
A Bakan, I Bahar
Proceedings of the National Academy of Sciences 106 (34), 14349-14354, 2009
Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages
G Molina, A Vogt, A Bakan, W Dai, PQ De Oliveira, W Znosko, ...
Nature chemical biology 5 (9), 680-687, 2009
Evol and ProDy for bridging protein sequence evolution and structural dynamics
A Bakan, A Dutta, W Mao, Y Liu, C Chennubhotla, TR Lezon, I Bahar
Bioinformatics 30 (18), 2681-2683, 2014
In vitro platforms for evaluating liver toxicity
SS Bale, L Vernetti, N Senutovitch, R Jindal, M Hegde, A Gough, ...
Experimental biology and medicine 239 (9), 1180-1191, 2014
Druggability assessment of allosteric proteins by dynamics simulations in the presence of probe molecules
A Bakan, N Nevins, AS Lakdawala, I Bahar
Journal of chemical theory and computation 8 (7), 2435-2447, 2012
Pre‐existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteins
L Meireles, M Gur, A Bakan, I Bahar
Protein Science 20 (10), 1645-1658, 2011
Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans
A Bhushan, N Senutovitch, SS Bale, WJ McCarty, M Hegde, R Jindal, ...
Stem cell research & therapy 4 (1), 1-6, 2013
Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death
G Mustata, M Li, N Zevola, A Bakan, L Zhang, M Epperly, J S Greenberger, ...
Current topics in medicinal chemistry 11 (3), 281-290, 2011
In vivo structure–activity relationship studies support allosteric targeting of a dual specificity phosphatase
VN Korotchenko, M Saydmohammed, LL Vollmer, A Bakan, K Sheetz, ...
ChemBioChem 15 (10), 1436-1445, 2014
Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids
J Jiang, A Bakan, AA Kapralov, KI Silva, Z Huang, AA Amoscato, ...
Free Radical Biology and Medicine 71, 221-230, 2014
Coupling between catalytic loop motions and enzyme global dynamics
Z Kurkcuoglu, A Bakan, D Kocaman, I Bahar, P Doruker
Public Library of Science 8 (9), e1002705, 2012
Synthesis and biological evaluation of 3-aminoisoquinolin-1 (2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B
KMG Rosenker, WD Paquette, PA Johnston, ER Sharlow, A Vogt, ...
Bioorganic & medicinal chemistry 23 (12), 2810-2818, 2015
Toward a molecular understanding of the interaction of dual specificity phosphatases with substrates: insights from structure-based modeling and high throughput screening
A Bakan, JS Lazo, P Wipf, KM Brummond, I Bahar
Current medicinal chemistry 15 (25), 2536-2544, 2008
Computational generation inhibitor-bound conformers of p38 map kinase and comparison with experiments
A Bakan, I Bahar
Biocomputing 2011, 181-192, 2011
Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library
JS Lazo, JJ Skoko, S Werner, B Mitasev, A Bakan, F Koizumi, ...
Journal of Pharmacology and Experimental Therapeutics 322 (3), 940-947, 2007
Inhibition of peroxidase activity of cytochrome c: de novo compound discovery and validation
A Bakan, AA Kapralov, H Bayir, F Hu, VE Kagan, I Bahar
Molecular pharmacology 88 (3), 421-427, 2015
Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents
ER Sharlow, P Wipf, KE McQueeney, A Bakan, JS Lazo
Expert Opinion on Investigational Drugs 23 (5), 661-673, 2014
Author's Accepted Manuscript
P Kaner, DJ Johnson, E Şeker, N Hilal, SA Altınkaya
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