Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate1 AP Pereira Da Silva, T El-Bacha, N Kyaw, RS Dos Santos, WS Da-Silva, ... Biochemical Journal 417 (3), 717-726, 2009 | 197 | 2009 |
Solution structure of Pisum sativum defensin 1 by high resolution NMR: plant defensins, identical backbone with different mechanisms of action MS Almeida, KMS Cabral, E Kurtenbach, FCL Almeida, AP Valente Journal of molecular biology 315 (4), 749-757, 2002 | 168 | 2002 |
Production of the active antifungal Pisum sativum defensin 1 (Psd1) in Pichia pastoris: overcoming the inefficiency of the STE13 protease KMS Cabral, MS Almeida, AP Valente, FCL Almeida, E Kurtenbach Protein Expression and Purification 31 (1), 115-122, 2003 | 140 | 2003 |
Peptide: lipid ratio and membrane surface charge determine the mechanism of action of the antimicrobial peptide BP100. Conformational and functional studies MC Manzini, KR Perez, KA Riske, JC Bozelli Jr, TL Santos, MA da Silva, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (7), 1985-1999, 2014 | 133 | 2014 |
Backbone dynamics of the antifungal Psd1 pea defensin and its correlation with membrane interaction by NMR spectroscopy LN de Medeiros, R Angeli, CG Sarzedas, E Barreto-Bergter, AP Valente, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (2), 105-113, 2010 | 121 | 2010 |
Fd coat protein structure in membrane environments: structural dynamics of the loop between the hydrophobic trans-membrane helix and the amphipathic in-plane helix FCL Almeida, SJ Opella Journal of molecular biology 270 (3), 481-495, 1997 | 120 | 1997 |
The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif IC Martins, F Gomes-Neto, AF Faustino, FA Carvalho, FA Carneiro, ... Biochemical Journal 444 (3), 405-415, 2012 | 112 | 2012 |
Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1) JL Abrantes, CM Alves, J Costa, FCL Almeida, M Sola-Penna, CFL Fontes, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (8 …, 2012 | 106 | 2012 |
Controlling β-amyloid oligomerization by the use of naphthalene sulfonates: Trapping low molecular weight oligomeric species AD Ferrão-Gonzales, BK Robbs, VH Moreau, A Ferreira, L Juliano, ... Journal of Biological Chemistry 280 (41), 34747-34754, 2005 | 106 | 2005 |
Dengue virus capsid protein interacts specifically with very low-density lipoproteins AF Faustino, FA Carvalho, IC Martins, MARB Castanho, ... Biophysical Journal 106 (2), 388a, 2014 | 87 | 2014 |
Solution NMR structures of the antimicrobial peptides phylloseptin-1,-2, and-3 and biological activity: the role of charges and hydrogen bonding interactions in stabilizing … JM Resende, CM Moraes, MV Prates, A Cesar, FCL Almeida, ... Peptides 29 (10), 1633-1644, 2008 | 85 | 2008 |
cDNA cloning and heterologous expression of functional cysteine-rich antifungal protein Psd1 in the yeast Pichia pastoris MS Almeida, KS Cabral, LN de Medeiros, AP Valente, FCL Almeida, ... Archives of Biochemistry and Biophysics 395 (2), 199-207, 2001 | 83 | 2001 |
From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway RJ Giordano, M Cardó-Vila, A Salameh, CD Anobom, BD Zeitlin, ... Proceedings of the National Academy of Sciences 107 (11), 5112-5117, 2010 | 81 | 2010 |
Salivary metabolite signatures of children with and without dental caries lesions TKS Fidalgo, LB Freitas-Fernandes, R Angeli, AMS Muniz, E Gonsalves, ... Metabolomics 9, 657-666, 2013 | 77 | 2013 |
Structure of the Ebola fusion peptide in a membrane-mimetic environment and the interaction with lipid rafts MS Freitas, LP Gaspar, M Lorenzoni, FCL Almeida, LW Tinoco, ... Journal of Biological Chemistry 282 (37), 27306-27314, 2007 | 72 | 2007 |
Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors ND Amoêdo, MF Rodrigues, P Pezzuto, A Galina, RM da Costa, ... PLoS One 6 (7), e22264, 2011 | 69 | 2011 |
Portrayal of complex dynamic properties of sugarcane defensin 5 by NMR: multiple motions associated with membrane interaction VS De Paula, G Razzera, E Barreto-Bergter, FCL Almeida, AP Valente Structure 19 (1), 26-36, 2011 | 65 | 2011 |
Interaction of the dengue virus fusion peptide with membranes assessed by NMR: the essential role of the envelope protein Trp101 for membrane fusion MN Melo, FJR Sousa, FA Carneiro, MARB Castanho, AP Valente, ... Journal of Molecular Biology 392 (3), 736-746, 2009 | 65 | 2009 |
Structure and membrane interactions of the antibiotic peptide dermadistinctin K by multidimensional solution and oriented 15N and 31P solid-state NMR spectroscopy RM Verly, CM De Moraes, JM Resende, C Aisenbrey, MP Bemquerer, ... Biophysical journal 96 (6), 2194-2203, 2009 | 65 | 2009 |
Understanding dengue virus capsid protein disordered N-terminus and pep14-23-based inhibition AF Faustino, GM Guerra, RG Huber, A Hollmann, MM Domingues, ... ACS Chemical Biology 10 (2), 517-526, 2015 | 64 | 2015 |