David A. Smith-Parkin
David A. Smith-Parkin
Other namesDavid A Smith
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Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus
MA Ansari, V Pedergnana, C LC Ip, A Magri, A Von Delft, D Bonsall, ...
Nature genetics 49 (5), 666-673, 2017
Resistance analysis of genotype 3 hepatitis C virus indicates subtypes inherently resistant to nonstructural protein 5A inhibitors
D Smith, A Magri, D Bonsall, CLC Ip, A Trebes, A Brown, P Piazza, ...
Hepatology 69 (5), 1861-1872, 2019
Efficacy of NS5A inhibitors against unusual and potentially difficult-to-treat HCV subtypes commonly found in sub-Saharan Africa and South East Asia
D Nguyen, D Smith, A Vaughan-Jackson, A Magri, E Barnes, P Simmonds, ...
Journal of Hepatology 73 (4), 794-799, 2020
An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression
E Cano-Gamez, KL Burnham, C Goh, A Allcock, ZH Malick, L Overend, ...
Science translational medicine 14 (669), eabq4433, 2022
Amino acid substitutions in genotype 3a hepatitis C virus polymerase protein affect responses to sofosbuvir
PAC Wing, M Jones, M Cheung, S DaSilva, C Bamford, WYJ Lee, ...
Gastroenterology 157 (3), 692-704. e9, 2019
Interpreting viral deep sequencing data with GLUE
JB Singer, EC Thomson, J Hughes, E Aranday-Cortes, J McLauchlan, ...
Viruses 11 (4), 323, 2019
Real world SOF/VEL/VOX retreatment outcomes and viral resistance analysis for HCV patients with prior failure to DAA therapy
DA Smith, D Bradshaw, JL Mbisa, CF Manso, DF Bibby, JB Singer, ...
Journal of Viral Hepatitis 28 (9), 1256-1264, 2021
Electronic health informatics data to describe clearance dynamics of hepatitis B surface antigen (HBsAg) and e antigen (HBeAg) in chronic hepatitis B virus infection
LO Downs, DA Smith, SF Lumley, M Patel, AL McNaughton, J Mokaya, ...
MBio 10 (3), 10.1128/mbio. 00699-19, 2019
Treatment advantage in HBV/HIV coinfection compared to HBV monoinfection in a South African cohort
TG Maponga, AL McNaughton, M Van Schalkwyk, S Hugo, C Nwankwo, ...
Journal of Infection 81 (1), 121-130, 2020
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
DA Smith, C Fernandez-Antunez, A Magri, R Bowden, N Chaturvedi, ...
Nature communications 12 (1), 6105, 2021
Hepatitis B virus (HBV) viral load, liver and renal function in adults treated with tenofovir disoproxil fumarate (TDF) vs. untreated: a retrospective longitudinal UK cohort study
T Wang, DA Smith, C Campbell, J Mokaya, O Freeman, H Salih, ...
BMC infectious diseases 21 (1), 610, 2021
National Institute for Health Research Health Informatics Collaborative: development of a pipeline to collate electronic clinical data for viral hepatitis research
DA Smith, T Wang, O Freeman, C Crichton, H Salih, PC Matthews, ...
BMJ health & care informatics 27 (3), 2020
Bimodal distribution and set point HBV DNA viral loads in chronic infection: retrospective analysis of cohorts from the UK and South Africa
LO Downs, S Vawda, PA Bester, KA Lythgoe, T Wang, AL McNaughton, ...
Wellcome Open Research 5, 2020
Longitudinal analysis of the utility of liver biochemistry as prognostic markers in hospitalized patients with corona virus disease 2019
T Wang, DA Smith, C Campbell, S Harris, H Salih, KA Várnai, K Woods, ...
Hepatology Communications 5 (9), 1586-1604, 2021
Cohort Profile: The National Institute for Health Research Health Informatics Collaborative: Hepatitis B Virus (NIHR HIC HBV) research dataset
T Wang, DA Smith, C Campbell, O Freeman, Z Moysova, T Noble, ...
International Journal of Epidemiology 52 (1), e27-e37, 2023
Strategic treatment optimization for HCV (STOPHCV1): a randomised controlled trial of ultrashort duration therapy for chronic hepatitis C
GS Cooke, S Pett, L McCabe, C Jones, R Gilson, S Verma, SD Ryder, ...
Wellcome Open Research 6, 2021
High cure rates for hepatitis c virus genotype 6 in advanced liver fibrosis with 12 weeks sofosbuvir and daclatasvir: the vietnam SEARCH study
B Flower, L McCabe, C Le Ngoc, H Le Manh, P Le Thanh, T Dang Trong, ...
Open forum infectious diseases 8 (7), ofab267, 2021
Characterization of hepatitis C virus resistance to grazoprevir reveals complex patterns of mutations following on-treatment breakthrough that are not observed at relapse
D Bonsall, S Black, AYM Howe, R Chase, P Ingravallo, I Pak, A Brown, ...
Infection and Drug Resistance, 1119-1135, 2018
High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from a large community-based surveillance study
M Ghafari, M Hall, T Golubchik, D Ayoubkhani, T House, ...
medRxiv, 2023.01. 29.23285160, 2023
Impact of the COVID-19 pandemic on routine surveillance for adults with chronic hepatitis B virus (HBV) infection in the UK
C Campbell, T Wang, DA Smith, O Freeman, T Noble, KA Várnai, S Harris, ...
Wellcome Open Research 7, 2022
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