Genomic responses in mouse models poorly mimic human inflammatory diseases J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ... Proceedings of the National Academy of Sciences 110 (9), 3507-3512, 2013 | 3187 | 2013 |
A network-based analysis of systemic inflammation in humans SE Calvano, W Xiao, DR Richards, RM Felciano, HV Baker, RJ Cho, ... Nature 437 (7061), 1032-1037, 2005 | 1684 | 2005 |
Sepsis and septic shock RS Hotchkiss, LL Moldawer, SM Opal, K Reinhart, IR Turnbull, JL Vincent Nature reviews Disease primers 2 (1), 1-21, 2016 | 1522 | 2016 |
A genomic storm in critically injured humans W Xiao, MN Mindrinos, J Seok, J Cuschieri, AG Cuenca, H Gao, ... Journal of Experimental Medicine 208 (13), 2581-2590, 2011 | 1291 | 2011 |
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. KJ Van Zee, T Kohno, E Fischer, CS Rock, LL Moldawer, SF Lowry Proceedings of the National Academy of Sciences 89 (11), 4845-4849, 1992 | 1091 | 1992 |
Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia. Y Fong, KJ Tracey, LL Moldawer, DG Hesse, KB Manogue, JS Kenney, ... The Journal of experimental medicine 170 (5), 1627-1633, 1989 | 919 | 1989 |
Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care LF Gentile, AG Cuenca, PA Efron, D Ang, A Bihorac, BA McKinley, ... Journal of Trauma and Acute Care Surgery 72 (6), 1491-1501, 2012 | 879 | 2012 |
Anti-TNF-α therapies: the next generation MA Palladino, FR Bahjat, EA Theodorakis, LL Moldawer Nature reviews Drug discovery 2 (9), 736-746, 2003 | 839 | 2003 |
MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis MJ Delano, PO Scumpia, JS Weinstein, D Coco, S Nagaraj, ... The Journal of experimental medicine 204 (6), 1463-1474, 2007 | 821 | 2007 |
Sepsis syndromes: understanding the role of innate and acquired immunity A Oberholzer, C Oberholzer, LL Moldawer Shock 16 (2), 83-96, 2001 | 783 | 2001 |
Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. SD Wolpe, G Davatelis, B Sherry, B Beutler, DG Hesse, HT Nguyen, ... The Journal of experimental medicine 167 (2), 570-581, 1988 | 731 | 1988 |
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Genomic responses in mouse models poorly mimic human inflammatory diseases J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ... Proc Natl Acad Sci USA 110 (9), 3507-3512, 2013 | 549 | 2013 |
Structural basis for the proinflammatory cytokine activity of high mobility group box 1 J Li, R Kokkola, S Tabibzadeh, R Yang, M Ochani, X Qiang, HE Harris, ... Molecular medicine 9, 37-45, 2003 | 549 | 2003 |
Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins Y Fong, LL Moldawer, M Marano, H Wei, A Barber, K Manogue, KJ Tracey, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 1989 | 507 | 1989 |
Sepsis pathophysiology, chronic critical illness, and persistent inflammation-immunosuppression and catabolism syndrome JC Mira, LF Gentile, BJ Mathias, PA Efron, SC Brakenridge, AM Mohr, ... Critical care medicine 45 (2), 253-262, 2017 | 495 | 2017 |
Cytokine signaling-regulation of the immune response in normal and critically ill states A Oberholzer, C Oberholzer, LL Moldawer Critical care medicine 28 (4), N3-N12, 2000 | 468 | 2000 |
The biologic characteristics of cytokines and their implication in surgical injury. Y Fong, LL Moldawer, GT Shires, SF Lowry Surgery, gynecology & obstetrics 170 (4), 363-378, 1990 | 463 | 1990 |
The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans. YM Fong, MA Marano, LL Moldawer, H Wei, SE Calvano, JS Kenney, ... The Journal of clinical investigation 85 (6), 1896-1904, 1990 | 459 | 1990 |
A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia. HS Ginsberg, LL Moldawer, PB Sehgal, M Redington, PL Kilian, ... Proceedings of the National Academy of Sciences 88 (5), 1651-1655, 1991 | 436 | 1991 |
Cost and mortality associated with postoperative acute kidney injury C Hobson, T Ozrazgat-Baslanti, A Kuxhausen, P Thottakkara, PA Efron, ... Annals of surgery 261 (6), 1207-1214, 2015 | 430 | 2015 |