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Frank Staal
Frank Staal
IHB, Molecular Stem Cell Biology LUMC, Universiteit Leiden
Verified email at lumc.nl - Homepage
Title
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Cited by
Year
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
SJ Howe, MR Mansour, K Schwarzwaelder, C Bartholomae, M Hubank, ...
The Journal of clinical investigation 118 (9), 2008
12912008
Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.
FJ Staal, M Roederer, LA Herzenberg, LA Herzenberg
Proceedings of the National Academy of Sciences 87 (24), 9943-9947, 1990
12091990
Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes
CJM Loomans, EJP de Koning, FJT Staal, MB Rookmaaker, C Verseyden, ...
Diabetes 53 (1), 195-199, 2004
11022004
WNT signalling in the immune system: WNT is spreading its wings
FJT Staal, TC Luis, MM Tiemessen
Nature Reviews Immunology 8 (8), 581-593, 2008
6402008
Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine.
M Roederer, FJ Staal, PA Raju, SW Ela, LA Herzenberg, LA Herzenberg
Proceedings of the National Academy of Sciences 87 (12), 4884-4888, 1990
5261990
Glutathione deficiency and human immunodeficiency virus infection.
FJT Staal, SW Ela
The Lancet 339 (8798), 909-912, 1992
5221992
Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway.
MT Anderson, FJ Staal, C Gitler, LA Herzenberg, LA Herzenberg
Proceedings of the National Academy of Sciences 91 (24), 11527-11531, 1994
4551994
WNT signalling and haematopoiesis: a WNT–WNT situation
FJT Staal, HC Clevers
Nature Reviews Immunology 5 (1), 21-30, 2005
4292005
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling
WA Dik, K Pike-Overzet, F Weerkamp, D de Ridder, EFE de Haas, ...
The Journal of experimental medicine 201 (11), 1715-1723, 2005
4172005
Wnt signals are transmitted through N-terminally dephosphorylated β-catenin
FJT Staal, M van Noort, GJ Strous, HC Clevers
EMBO reports 3 (1), 63-68, 2002
4022002
A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes
RC Padmos, MHJ Hillegers, EM Knijff, R Vonk, A Bouvy, FJT Staal, ...
Archives of general psychiatry 65 (4), 395-407, 2008
3742008
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia
I Homminga, R Pieters, AW Langerak, JJ de Rooi, A Stubbs, M Verstegen, ...
Cancer cell 19 (4), 484-497, 2011
3652011
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion
TC Luis, BAE Naber, PPC Roozen, MH Brugman, EFE de Haas, ...
Cell stem cell 9 (4), 345-356, 2011
3322011
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
C Baum, C Von Kalle, FJT Staal, Z Li, B Fehse, M Schmidt, F Weerkamp, ...
Molecular Therapy 9 (1), 5-13, 2004
2962004
Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.
FJ Staal, MT Anderson, GE Staal, LA Herzenberg, C Gitler, ...
Proceedings of the National Academy of Sciences 91 (9), 3619-3622, 1994
2811994
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
A Deichmann, S Hacein-Bey-Abina, M Schmidt, A Garrigue, MH Brugman, ...
The Journal of clinical investigation 117 (8), 2225-2232, 2007
2802007
Wnt signaling is required for thymocyte development and activates Tcf‐1 mediated transcription
FJT Staal, J Meeldijk, P Moerer, P Jay, BCM van de Weerdt, S Vainio, ...
European journal of immunology 31 (1), 285-293, 2001
2722001
CD34+ CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells
P Res, E Martinez-Caceres, A Cristina Jaleco, F Staal, E Noteboom, ...
2501996
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
K Schwarzwaelder, SJ Howe, M Schmidt, MH Brugman, A Deichmann, ...
The Journal of clinical investigation 117 (8), 2241-2249, 2007
2322007
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
TC Luis, F Weerkamp, BAE Naber, MRM Baert, EFE de Haas, T Nikolic, ...
Blood, The Journal of the American Society of Hematology 113 (3), 546-554, 2009
2292009
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