Ana Cristina Lima Leite
Ana Cristina Lima Leite
Professor de Ciências Farmacêuticas da Universidade Federal de Pernambuco
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Halogen atoms in the modern medicinal chemistry: hints for the drug design
MZ Hernandes, SMT Cavalcanti, DRM Moreira, WF de Azevedo Junior, ...
Current drug targets 11 (3), 303-314, 2010
Synthesis, anticancer activity and mechanism of action of new thiazole derivatives
TI de Santana, M de Oliveira Barbosa, PAT de Moraes Gomes, ...
European journal of medicinal chemistry 144, 874-886, 2018
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi
ACL Leite, RS de Lima, DRM Moreira, MVO Cardoso, ACG de Brito, ...
Bioorganic & medicinal chemistry 14 (11), 3749-3757, 2006
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues
LRP de Siqueira, PAT de Moraes Gomes, LP de Lima Ferreira, ...
European Journal of Medicinal Chemistry 170, 237-260, 2019
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation
MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ...
European Journal of Medicinal Chemistry 86, 48-59, 2014
Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1, 2, 4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents
JM dos Santos Filho, ACL Leite, BG de Oliveira, DRM Moreira, MS Lima, ...
Bioorganic & medicinal chemistry 17 (18), 6682-6691, 2009
Approaches for the development of new anti-Trypanosoma cruzi agents
DR Magalhaes Moreira, AC Lima Leite, RR Santos, MBP Soares
Current Drug Targets 10 (3), 212-231, 2009
Synthesis, antitumour and antimicrobial activities of new peptidyl derivatives containing the 1, 3-benzodioxole system
ACL Leite, KP da Silva, IA de Souza, JM de Araújo, DJ Brondani
European journal of medicinal chemistry 39 (12), 1059-1065, 2004
Synthesis, Cruzain Docking, and in vitro Studies of Aryl‐4‐Oxothiazolylhydrazones Against Trypanosoma cruzi
ACL Leite, DR de M. Moreira, MV de O. Cardoso, MZ Hernandes, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (9), 1339-1345, 2007
Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents
A Inam, SM Siddiqui, TS Macedo, DRM Moreira, ACL Leite, MBP Soares, ...
European Journal of Medicinal Chemistry 75, 67-76, 2014
Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice
DRM Moreira, SPM Costa, MZ Hernandes, MM Rabello, ...
Journal of Medicinal Chemistry 55 (24), 10918-10936, 2012
Physicochemical properties, fatty acid profile and sensory characteristics of sheep and goat meat sausages manufactured with different pork fat levels
A Leite, S Rodrigues, E Pereira, K Paulos, AF Oliveira, JM Lorenzo, ...
Meat science 105, 114-120, 2015
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents
MZ Hernandes, MM Rabello, ACL Leite, MVO Cardoso, DRM Moreira, ...
Bioorganic & Medicinal Chemistry 18 (22), 7826-7835, 2010
Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma Cruzi Cruzain
JWP Espíndola, MV de Oliveira Cardoso, GB de Oliveira Filho, ...
European Journal of Medicinal Chemistry 101, 818-835, 2015
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death
DRM Moreira, ADT de Oliveira, PAT de Moraes Gomes, CA de Simone, ...
European journal of medicinal chemistry 75, 467-478, 2014
Antitumor and immunomodulatory activities of thiosemicarbazones and 1, 3-Thiazoles in Jurkat and HT-29 cells
TAR Dos Santos, AC da Silva, EB Silva, PAT de Moraes Gomes, ...
Biomedicine & Pharmacotherapy 82, 555-560, 2016
New 1, 3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi
PAT de Moraes Gomes, M de Oliveira Barbosa, EF Santiago, ...
European Journal of Medicinal Chemistry 121, 387-398, 2016
In vitro trypanocidal activity of phenolic derivatives from Peperomia obtusifolia
J da Silva Mota, AC Leite, JMB Junior, SN López, DL Ambrósio, ...
Planta medica 75 (06), 620-623, 2009
Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles
EF Santiago, SA de Oliveira, GB de Oliveira Filho, DRM Moreira, ...
Antimicrobial agents and chemotherapy 58 (1), 352-363, 2014
Structural Design, Synthesis and Structure–Activity Relationships of Thiazolidinones with Enhanced Anti‐Trypanosoma cruzi Activity
DRM Moreira, AC Lima Leite, MVO Cardoso, RM Srivastava, ...
ChemMedChem 9 (1), 177-188, 2014
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