| Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity SA Smallwood, HJ Lee, C Angermueller, F Krueger, H Saadeh, J Peat, ... Nature methods 11 (8), 817-820, 2014 | 1159 | 2014 |
| Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity C Angermueller, SJ Clark, HJ Lee, IC Macaulay, MJ Teng, TX Hu, ... Nature Methods, 2016 | 736 | 2016 |
| Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ... Nature 468 (7320), 98-102, 2010 | 644 | 2010 |
| scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells SJ Clark, R Argelaguet, CA Kapourani, TM Stubbs, HJ Lee, ... Nature communications 9 (1), 781, 2018 | 617 | 2018 |
| DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning C Angermueller, HJ Lee, W Reik, O Stegle Genome Biology 18 (1), 67, 2017 | 584 | 2017 |
| FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency G Ficz, TA Hore, F Santos, HJ Lee, W Dean, J Arand, F Krueger, D Oxley, ... Cell stem cell 13 (3), 351-359, 2013 | 448 | 2013 |
| Reprogramming the Methylome: Erasing Memory and Creating Diversity HJ Lee, TA Hore, W Reik Cell Stem Cell 14 (6), 710-719, 2014 | 399 | 2014 |
| Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity SJ Clark, HJ Lee, SA Smallwood, G Kelsey, W Reik Genome Biology 17 (1), 1, 2016 | 322 | 2016 |
| A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ... Cancer Cell 36 (6), 660-673. e11, 2019 | 298 | 2019 |
| Tracking the embryonic stem cell transition from ground state pluripotency T Kalkan, N Olova, M Roode, C Mulas, HJ Lee, I Nett, H Marks, R Walker, ... Development, dev. 142711, 2017 | 286 | 2017 |
| Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq) SJ Clark, SA Smallwood, HJ Lee, F Krueger, W Reik, G Kelsey Nature Protocols 12 (3), 534-547, 2017 | 241 | 2017 |
| Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ... Development 140 (7), 1397-1401, 2013 | 118 | 2013 |
| ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS biology 10 (12), e1001461, 2012 | 104 | 2012 |
| Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants KK Menzies, HJ Lee, C Lefèvre, CJ Ormandy, KL Macmillan, KR Nicholas Functional & integrative genomics 10 (1), 87-95, 2010 | 87 | 2010 |
| Genome-scale oscillations in DNA methylation during exit from pluripotency S Rulands, HJ Lee, SJ Clark, C Angermueller, SA Smallwood, F Krueger, ... Cell Systems 7 (1), 63-76.E12, 2018 | 84 | 2018 |
| ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. D Gallego-Ortega, A Ledger, DL Roden, AM Law, A Magenau, Z Kikhtyak, ... PLoS biology 13 (12), e1002330-e1002330, 2015 | 79 | 2015 |
| Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation H Lee, H Mun, N Lewis, M Crouch, E Culverston, R Mason, A Conigrave Biochem. J 404, 141-149, 2007 | 72 | 2007 |
| Interplay between progesterone and prolactin in mammary development and implications for breast cancer HJ Lee, CJ Ormandy Molecular and Cellular Endocrinology 357 (1), 101-107, 2012 | 66 | 2012 |
| Lineage specific methylation of the Elf5 promoter in mammary epithelial cells HJ Lee, RA Hinshelwood, T Bouras, D Gallego‐Ortega, F Valdés‐Mora, ... Stem Cells 29 (10), 1611-1619, 2011 | 58 | 2011 |
| Elf5, hormones and cell fate HJ Lee, CJ Ormandy Trends in Endocrinology & Metabolism 23 (6), 292-298, 2012 | 48 | 2012 |
Wolf ReikHead, Epigenetics Programme, Babraham Institute Cambridge, UKVerified email at babraham.ac.uk
