SARS-CoV-2 productively infects human gut enterocytes MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ... Science 369 (6499), 50-54, 2020 | 1718 | 2020 |
An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells MM Lamers, J van Der Vaart, K Knoops, S Riesebosch, TI Breugem, ... The EMBO journal 40 (5), e105912, 2021 | 190 | 2021 |
Intestinal regeneration: regulation by the microenvironment JH Hageman, MC Heinz, K Kretzschmar, J van der Vaart, H Clevers, ... Developmental cell 54 (4), 435-446, 2020 | 120 | 2020 |
Airway organoids as models of human disease J van der Vaart, H Clevers Journal of internal medicine 289 (5), 604-613, 2021 | 78 | 2021 |
Exploring the human lacrimal gland using organoids and single-cell sequencing M Bannier-Hélaouët, Y Post, J Korving, MT Bustos, H Gehart, H Begthel, ... Cell stem cell 28 (7), 1221-1232. e7, 2021 | 70 | 2021 |
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ... Nature communications 12 (1), 5498, 2021 | 68 | 2021 |
NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor L Novellasdemunt, A Kucharska, C Jamieson, M Prange‐Barczynska, ... The EMBO journal 39 (3), e102771, 2020 | 67 | 2020 |
Advancing lung organoids for COVID-19 research J van der Vaart, MM Lamers, BL Haagmans, H Clevers Disease Models & Mechanisms 14 (6), dmm049060, 2021 | 41 | 2021 |
Adult mouse and human organoids derived from thyroid follicular cells and modeling of Graves’ hyperthyroidism J van der Vaart, L Bosmans, SF Sijbesma, K Knoops, WJ van de Wetering, ... Proceedings of the National Academy of Sciences 118 (51), e2117017118, 2021 | 31 | 2021 |
Modelling of primary ciliary dyskinesia using patient‐derived airway organoids J Van der Vaart, L Böttinger, MH Geurts, WJ Van de Wetering, K Knoops, ... EMBO reports 22 (12), e52058, 2021 | 26 | 2021 |
The organoid platform: promises and challenges as tools in the fight against COVID-19 MH Geurts, J van der Vaart, J Beumer, H Clevers Stem Cell Reports 16 (3), 412-418, 2021 | 26 | 2021 |
Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7 MM Lamers, TI Breugem, AZ Mykytyn, Y Wang, N Groen, K Knoops, ... BioRxiv, 2021.05. 03.441080, 2021 | 11 | 2021 |
RSPO3 Furin domain-conjugated liposomes for selective drug delivery to LGR5-high cells P van Kerkhof, T Kralj, F Spanevello, L van Bloois, I Jordens, ... Journal of Controlled Release 356, 72-83, 2023 | | 2023 |
Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway SF Plugge, H Ma, JY van der Vaart, J Sprangers, FHM Morsink, ... bioRxiv, 2023.07. 17.548873, 2023 | | 2023 |
Modelling of a wide variety of disease using adult stem cell-derived organoids J van der Vaart | | 2022 |
Extended Shedding and Enhanced Fitness of the SARS-CoV-2 Variant of Concern B. 1.1. 7 in Human Organoid Systems MM Lamers, TI Breugem, AZ Mykytyn, Y Wang, N Groen, K Knoops, ... | | 2021 |
Extended Shedding and Enhanced Fitness of the SARS-CoV-2 Variant of Concern B. 1.1. 7 in Human Organoid Systems (preprint) MM Lamers, T Breugem, A Mykytyn, Y Wang, N Groen, K Knoops, ... | | 2021 |
Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B. 1.1. 7 (preprint) MM Lamers, TI Breugem, AZ Mykytyn, Y Wang, N Groen, K Knoops, ... | | 2021 |
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses (preprint) J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ... | | 2021 |
SARS-CoV-2 Productively Infects Human Gut Enterocytes (preprint) MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ... | | 2020 |