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Andrew Chris Yang
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A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
Nature 583 (7817), 590-595, 2020
7672020
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
D Gate, N Saligrama, O Leventhal, AC Yang, MS Unger, J Middeldorp, ...
Nature 577 (7790), 399-404, 2020
6162020
Dysregulation of brain and choroid plexus cell types in severe COVID-19
AC Yang, F Kern, PM Losada, MR Agam, CA Maat, GP Schmartz, ...
Nature 595 (7868), 565-571, 2021
5292021
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk
AC Yang, RT Vest, F Kern, DP Lee, M Agam, CA Maat, PM Losada, ...
Nature 603 (7903), 885-892, 2022
380*2022
Ageing hallmarks exhibit organ-specific temporal signatures
N Schaum, B Lehallier, O Hahn, R Pálovics, S Hosseinzadeh, SE Lee, ...
Nature 583 (7817), 596-602, 2020
3722020
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
JV Pluvinage, MS Haney, BAH Smith, J Sun, T Iram, L Bonanno, L Li, ...
Nature 568 (7751), 187-192, 2019
3292019
Physiological blood–brain transport is impaired with age by a shift in transcytosis
AC Yang, MY Stevens, MB Chen, DP Lee, D Stähli, D Gate, K Contrepois, ...
Nature 583 (7816), 425-430, 2020
3152020
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
H Yousef, CJ Czupalla, D Lee, MB Chen, AN Burke, KA Zera, J Zandstra, ...
Nature medicine 25 (6), 988-1000, 2019
3062019
Engineering phage host-range and suppressing bacterial resistance through phage tail fiber mutagenesis
K Yehl, S Lemire, AC Yang, H Ando, M Mimee, MDT Torres, ...
Cell 179 (2), 459-469. e9, 2019
2702019
Exercise plasma boosts memory and dampens brain inflammation via clusterin
Z De Miguel, N Khoury, MJ Betley, B Lehallier, D Willoughby, N Olsson, ...
Nature 600 (7889), 494-499, 2021
2012021
Brain endothelial cells are exquisite sensors of age-related circulatory cues
MB Chen, AC Yang, H Yousef, D Lee, W Chen, N Schaum, B Lehallier, ...
Cell reports 30 (13), 4418-4432. e4, 2020
1512020
An exercise-inducible metabolite that suppresses feeding and obesity
VL Li, Y He, K Contrepois, H Liu, JT Kim, AL Wiggenhorn, JT Tanzo, ...
Nature 606 (7915), 785-790, 2022
1392022
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17
T Iram, F Kern, A Kaur, S Myneni, AR Morningstar, H Shin, MA Garcia, ...
Nature 605 (7910), 509-515, 2022
1222022
CD4+ T cells contribute to neurodegeneration in Lewy body dementia
D Gate, E Tapp, O Leventhal, M Shahid, TJ Nonninger, AC Yang, ...
Science 374 (6569), 868-874, 2021
1042021
Cell type-selective secretome profiling in vivo
W Wei, NM Riley, AC Yang, JT Kim, SM Terrell, VL Li, M Garcia-Contreras, ...
Nature chemical biology 17 (3), 326-334, 2021
742021
Molecular hallmarks of heterochronic parabiosis at single-cell resolution
R Pálovics, A Keller, N Schaum, W Tan, T Fehlmann, M Borja, F Kern, ...
Nature 603 (7900), 309-314, 2022
632022
Organ aging signatures in the plasma proteome track health and disease
HSH Oh, J Rutledge, D Nachun, R Pálovics, O Abiose, P Moran-Losada, ...
Nature 624 (7990), 164-172, 2023
372023
Synthetic bacteriophages and bacteriophage compositions
TKT Lu, S Lemire, AC Yang, KM Yehl
US Patent 10,626,394, 2020
352020
Multiple click-selective tRNA synthetases expand mammalian cell-specific proteomics
AC Yang, H Du Bois, N Olsson, D Gate, B Lehallier, D Berdnik, KD Brewer, ...
Journal of the American Chemical Society 140 (23), 7046-7051, 2018
302018
Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration
RT Vest, CC Chou, H Zhang, MS Haney, L Li, NN Laqtom, B Chang, ...
Proceedings of the National Academy of Sciences 119 (11), e2121609119, 2022
222022
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