Marc G. Caron

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Robert J. LefkowitzJames B. Duke Professor of Medicine, Biochemistry, Chemistry; HHMI, Duke UniversityVerified email at receptor-biol.duke.edu
Raul R. GainetdinovInstitute of Translational Biomedicine St. Petersburg State UniversityVerified email at spbu.ru
Jeffrey BenovicThomas Eakins Professor of Biochemistry and Molecular Biology, Thomas Jefferson UniversityVerified email at jefferson.edu
Bruno GirosDouglas Research Institute - McGill UniversityVerified email at mcgill.ca
Brian KobilkaStanford UniversityVerified email at stanford.edu
Jean Martin BeaulieuDepartment of Pharmacology and Toxicology, University of TorontoVerified email at utoronto.ca
Stephane A. LaporteProfessor of Medicine, McGill UniversityVerified email at mcgill.ca
Stephen SG FergusonUniversity of Ottawa Brain and Mind Institute, Department of Cellular MedicineVerified email at uottawa.ca
Sara JonesProfessor, Department of Physiology and Pharmacology, Wake Forest School of MedicineVerified email at wakehealth.edu
Henrik DohlmanProfessor of Pharmacology, University of North CarolinaVerified email at med.unc.edu
Michel BouvierProfessor of Biochem. and Mol. Med., IRIC, Univ. de MontréalVerified email at umontreal.ca
Laura M. Bohn, PhDThe Herbert Wertheim UF Scripps Biomedical Institute for Technology & InnovationVerified email at ufl.edu
R. Mark WightmanProfessor of Chemistry, University of North Carolina at chapel hillVerified email at unc.edu
Jon LomasneyAssociate Professor of Pathology, Northwestern UniversityVerified email at northwestern.edu
Xiaodong ZhangDuke-NUS Graduate Medical School SingaporeVerified email at duke-nus.edu.sg
Sheila CollinsVanderbilt University Medical CenterVerified email at vanderbilt.edu
Jay A. GingrichSackler Institute Columbia UniversityVerified email at columbia.edu
Richard T PremontHarrington Discovery Institute, Case, Duke, Mt SinaiVerified email at case.edu
Ramona RodriguizResearch Associate, PhD, Assistant Director Mouse Behavioral Core, Duke UniversityVerified email at mc.duke.edu
Nikhil UrsAssistant Professor, University of FloridaVerified email at ufl.edu

Marc G. Caron

James B. Duke Professor, Cell Biology, Medicine, Neurobiology Duke University

Verified email at duke.edu - Homepage

GPCR Signaling Psychiatric Disorders Addiction Drug Discovery


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Dopamine receptors: from structure to function C Missale, SR Nash, SW Robinson, M Jaber, MG Caron Physiological reviews 78 (1), 189-225, 1998	4506	1998
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter B Giros, M Jaber, SR Jones, RM Wightman, MG Caron Nature 379 (6566), 606-612, 1996	2975	1996
Model systems for the study of seven-transmembrane-segment receptors HG Dohlman, J Thorner, MG Caron, RJ Lefkowitz Annual review of biochemistry 60 (1), 653-688, 1991	1872	1991
β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes LM Luttrell, S Ferguson, Y Daaka, WE Miller, S Maudsley, GJ Della Rocca, ... Science 283 (5402), 655-661, 1999	1851	1999
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ... Nature 321 (6065), 75-79, 1986	1718	1986
Turning off the signal: desensitization of β‐adrenergic receptor function WP Hausdorff, MG Caron, RJ Lefkowitz The FASEB Journal 4 (11), 2881-2889, 1990	1695	1990
β-Arrestin: a protein that regulates β-adrenergic receptor function MJ Lohse, JL Benovic, J Codina, MG Caron, RJ Lefkowitz Science 248 (4962), 1547-1550, 1990	1546	1990
Mice with reduced NMDA receptor expression display behaviors related to schizophrenia AR Mohn, RR Gainetdinov, MG Caron, BH Koller Cell 98 (4), 427-436, 1999	1289	1999
Plasma membrane monoamine transporters: structure, regulation and function GE Torres, RR Gainetdinov, MG Caron Nature Reviews Neuroscience 4 (1), 13-25, 2003	1227	2003
Enhanced morphine analgesia in mice lacking β-arrestin 2 LM Bohn, RJ Lefkowitz, RR Gainetdinov, K Peppel, MG Caron, FT Lin Science 286 (5449), 2495-2498, 1999	1197	1999
Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization SSG Ferguson, WE Downey III, AM Colapietro, LS Barak, L Ménard, ... Science 271 (5247), 363-366, 1996	1177	1996
An Akt/β-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior JM Beaulieu, TD Sotnikova, S Marion, RJ Lefkowitz, RR Gainetdinov, ... Cell 122 (2), 261-273, 2005	1148	2005
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence LM Bohn, RR Gainetdinov, FT Lin, RJ Lefkowitz, MG Caron Nature 408 (6813), 720-723, 2000	1088	2000
Chimeric α₂-,β₂-Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity BK Kobilka, TS Kobilka, K Daniel, JW Regan, MG Caron, RJ Lefkowitz Science 240 (4857), 1310-1316, 1988	1049	1988
Differential affinities of visual arrestin, βarrestin1, and βarrestin2 for G protein-coupled receptors delineate two major classes of receptors RH Oakley, SA Laporte, JA Holt, MG Caron, LS Barak Journal of Biological Chemistry 275 (22), 17201-17210, 2000	1038	2000
Recent advances in the molecular biology of dopamine receptors JA Gingrich, MG Caron Annual review of neuroscience 16 (1), 299-321, 1993	1037	1993
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity RR Gainetdinov, WC Wetsel, SR Jones, ED Levin, M Jaber, MG Caron science 283 (5400), 397-401, 1999	1026	1999
Desensitization of G protein–coupled receptors and neuronal functions RR Gainetdinov, RT Premont, LM Bohn, RJ Lefkowitz, MG Caron Annu. Rev. Neurosci. 27, 107-144, 2004	1015	2004
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α₂-Adrenergic Receptor BK Kobilka, H Matsui, TS Kobilka, TL Yang-Feng, U Francke, MG Caron, ... Science 238 (4827), 650-656, 1987	978	1987
Cloning and expression of a functional serotonin transporter from rat brain RD Blakely, HE Berson, RT Fremeau Jr, MG Caron, MM Peek, HK Prince, ... Nature 354 (6348), 66-70, 1991	974	1991

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