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Rene Bernards
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Gene expression profiling predicts clinical outcome of breast cancer
LJ Van't Veer, H Dai, MJ Van De Vijver, YD He, AAM Hart, M Mao, ...
nature 415 (6871), 530-536, 2002
114602002
A gene-expression signature as a predictor of survival in breast cancer
MJ Van De Vijver, YD He, LJ Van't Veer, H Dai, AAM Hart, DW Voskuil, ...
New England Journal of Medicine 347 (25), 1999-2009, 2002
75132002
A system for stable expression of short interfering RNAs in mammalian cells
TR Brummelkamp, R Bernards, R Agami
science 296 (5567), 550-553, 2002
67672002
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
SH Friend, R Bernards, S Rogelj, RA Weinberg, JM Rapaport, DM Albert, ...
Nature 323 (6089), 643-646, 1986
37631986
The consensus molecular subtypes of colorectal cancer
J Guinney, R Dienstmann, X Wang, A De Reynies, A Schlicker, ...
Nature medicine 21 (11), 1350-1356, 2015
36512015
A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman, MPA Luna-Vargas, A Velds, TR Brummelkamp, AMG Dirac, ...
Cell 123 (5), 773-786, 2005
19872005
Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR
A Prahallad, C Sun, S Huang, F Di Nicolantonio, R Salazar, D Zecchin, ...
Nature 483 (7387), 100-103, 2012
19732012
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ...
Cancer cell 12 (4), 395-402, 2007
17882007
Stable suppression of tumorigenicity by virus-mediated RNA interference
TR Brummelkamp, R Bernards, R Agami
Cancer cell 2 (3), 243-247, 2002
16892002
70-gene signature as an aid to treatment decisions in early-stage breast cancer
F Cardoso, LJ van’t Veer, J Bogaerts, L Slaets, G Viale, S Delaloge, ...
New England Journal of Medicine 375 (8), 717-729, 2016
15582016
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
K Berns, EM Hijmans, J Mullenders, TR Brummelkamp, A Velds, ...
Nature 428 (6981), 431-437, 2004
14252004
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
TR Brummelkamp, SMB Nijman, AMG Dirac, R Bernards
Nature 424 (6950), 797-801, 2003
11972003
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
K Stemke-Hale, AM Gonzalez-Angulo, A Lluch, RM Neve, WL Kuo, ...
Cancer research 68 (15), 6084-6091, 2008
11202008
Metastasis genes: a progression puzzle
R Bernards, RA Weinberg
Nature 418 (6900), 823-823, 2002
10512002
CDK-independent activation of estrogen receptor by cyclin D1
RML Zwijsen, E Wientjens, R Klompmaker, J van der Sman, R Bernards, ...
Cell 88 (3), 405-415, 1997
8761997
Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma
C Sun, L Wang, S Huang, GJJE Heynen, A Prahallad, C Robert, ...
Nature 508 (7494), 118-122, 2014
7992014
The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
BD Rowland, R Bernards, DS Peeper
Nature cell biology 7 (11), 1074-1082, 2005
6912005
Enabling personalized cancer medicine through analysis of gene-expression patterns
LJ Van't Veer, R Bernards
Nature 452 (7187), 564-570, 2008
6612008
Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells
PI Schrier, R Bernards, R Vaessen, A Houweling, AJ Van der Eb
Nature 305 (5937), 771-775, 1983
6601983
Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
RM Kortlever, PJ Higgins, R Bernards
Nature cell biology 8 (8), 877-884, 2006
6462006
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