Jia-Yun Chen
Jia-Yun Chen
Harvard Medical School; Stanford University; National Taiwan University
Verified email at
Cited by
Cited by
TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase
CW Jang, CH Chen, CC Chen, J Chen, YH Su, RH Chen
Nature cell biology 4 (1), 51-58, 2002
Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12
X Wang, YC Wu, VA Fadok, MC Lee, K Gengyo-Ando, LC Cheng, ...
Science 302 (5650), 1563-1566, 2003
SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis
JR Lin, MK Zeman, JY Chen, MC Yee, KA Cimprich
Molecular cell 42 (2), 237-249, 2011
A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision
JY Chen, JR Lin, KA Cimprich, T Meyer
Molecular cell 45 (2), 196-209, 2012
Cyclic immunofluorescence (CycIF), a highly multiplexed method for single‐cell imaging
JR Lin, M Fallahi‐Sichani, JY Chen, PK Sorger
Current protocols in chemical biology 8 (4), 251-264, 2016
Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle
JY Chen, JR Lin, FC Tsai, T Meyer
Molecular cell 52 (1), 87-100, 2013
Fluctuations in p53 signaling allow escape from cell-cycle arrest
J Reyes, JY Chen, J Stewart-Ornstein, KW Karhohs, CS Mock, G Lahav
Molecular cell 71 (4), 581-591. e5, 2018
Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling
K Zhang, RFB Kenan, Y Osakada, W Xu, RS Sinit, L Chen, X Zhao, ...
Journal of Neuroscience 33 (17), 7451-7462, 2013
Receptor-driven ERK pulses reconfigure MAPK signaling and enable persistence of drug-adapted BRAF-mutant melanoma cells
L Gerosa, C Chidley, F Fröhlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ...
Cell systems 11 (5), 478-494. e9, 2020
A probabilistic approach to joint cell tracking and segmentation in high-throughput microscopy videos
A Arbelle, J Reyes, JY Chen, G Lahav, TR Raviv
Medical image analysis 47, 140-152, 2018
Torin2 exploits replication and checkpoint vulnerabilities to cause death of PI3K-activated triple-negative breast cancer cells
SS Chopra, A Jenney, A Palmer, M Niepel, M Chung, C Mills, ...
Cell systems 10 (1), 66-81. e11, 2020
Inhibition of haspin kinase promotes cell-intrinsic and extrinsic antitumor activity
JC Melms, S Vallabhaneni, CE Mills, C Yapp, JY Chen, E Morelli, ...
Cancer research 80 (4), 798-810, 2020
Fully unsupervised symmetry-based mitosis detection in time-lapse cell microscopy
T Gilad, J Reyes, JY Chen, G Lahav, T Riklin Raviv
Bioinformatics 35 (15), 2644-2653, 2019
C. elegans EIF-3. K promotes programmed cell death through CED-3 caspase
CY Huang, JY Chen, SC Wu, CH Tan, RY Tzeng, PJ Lu, YF Wu, RH Chen, ...
PLoS One 7 (5), e36584, 2012
Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
JY Chen, C Hug, J Reyes, C Tian, L Gerosa, F Fröhlich, B Ponsioen, ...
Cell reports 42 (3), 2023
Sporadic ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cells
L Gerosa, C Chidley, F Froehlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ...
BioRxiv, 762294, 2019
Fluctuations in p53 signaling allow escape from cell-cycle arrest
J Reyes, JY Chen, J Stewart-Ornstein, KW Karhohs, CS Mock, G Lahav
Molecular cell 73 (6), 1306, 2019
Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerability
S Ke, F Dang, L Wang, JY Chen, MT Naik, A Thavamani, Y Liu, W Li, ...
Research Square, 2023
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Articles 1–18