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Phillip Dumesic
Phillip Dumesic
Dana-Farber Cancer Institute, Damon Runyon Cancer Research Foundation
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Stalled spliceosomes are a signal for RNAi-mediated genome defense
PA Dumesic, P Natarajan, C Chen, IA Drinnenberg, BJ Schiller, ...
Cell 152 (5), 957-968, 2013
1832013
Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia
FA Scholl, PA Dumesic, DI Barragan, K Harada, V Bissonauth, J Charron, ...
Developmental cell 12 (4), 615-629, 2007
1782007
Product binding enforces the genomic specificity of a yeast polycomb repressive complex
PA Dumesic, CM Homer, JJ Moresco, LR Pack, EK Shanle, SM Coyle, ...
Cell 160 (1), 204-218, 2015
1302015
Erk1/2 MAP kinases are required for epidermal G2/M progression
PA Dumesic, FA Scholl, DI Barragan, PA Khavari
Journal of Cell Biology 185 (3), 409-422, 2009
1262009
Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase
S Catania, PA Dumesic, H Pimentel, A Nasif, CI Stoddard, JE Burke, ...
Cell 180 (2), 263-277. e20, 2020
992020
Mek1 alters epidermal growth and differentiation
FA Scholl, PA Dumesic, PA Khavari
Cancer research 64 (17), 6035-6040, 2004
892004
Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine
Y Sun, JF Rahbani, MP Jedrychowski, CL Riley, S Vidoni, D Bogoslavski, ...
Nature 593 (7860), 580-585, 2021
802021
Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions
JF Garcia, PA Dumesic, PD Hartley, H El-Samad, HD Madhani
Genes & development 24 (16), 1758-1771, 2010
742010
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia
FA Scholl, PA Dumesic, DI Barragan, K Harada, J Charron, PA Khavari
Cancer research 69 (9), 3772-3778, 2009
582009
Effects of active MEK1 expression in vivo
FA Scholl, PA Dumesic, PA Khavari
Cancer letters 230 (1), 1-5, 2005
572005
An evolutionarily conserved uORF regulates PGC1α and oxidative metabolism in mice, flies, and bluefin tuna
PA Dumesic, DF Egan, P Gut, MT Tran, A Parisi, N Chatterjee, ...
Cell metabolism 30 (1), 190-200. e6, 2019
472019
Ers1 links HP1 to RNAi
M Rougemaille, S Braun, S Coyle, PA Dumesic, JF Garcia, RS Isaac, ...
Proceedings of the National Academy of Sciences 109 (28), 11258-11263, 2012
372012
SnapShot: Regulation and biology of PGC-1α
PR Jannig, PA Dumesic, BM Spiegelman, JL Ruas
Cell 185 (8), 1444-1444. e1, 2022
362022
Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and …
SC Clarke, PA Dumesic, CM Homer, AJ O’Donoghue, F La Greca, ...
PLoS pathogens 12 (12), e1006051, 2016
362016
Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin
FA Scholl, PA Dumesic, DI Barragan, J Charron, PA Khavari
Oncogene 28 (12), 1485-1495, 2009
312009
Recognizing the enemy within: licensing RNA-guided genome defense
PA Dumesic, HD Madhani
Trends in biochemical sciences 39 (1), 25-34, 2014
282014
Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
MJ Mittenbühler, MP Jedrychowski, JG Van Vranken, HG Sprenger, ...
Cell Metabolism 35 (3), 535-549. e7, 2023
212023
Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal …
KL Leung, S Sanchita, CT Pham, BA Davis, M Okhovat, X Ding, ...
Clinical epigenetics 12, 1-16, 2020
212020
The spliceosome as a transposon sensor
PA Dumesic, HD Madhani
RNA biology 10 (11), 1653-1660, 2013
192013
ATP hydrolysis by the SNF2 domain of Dnmt5 is coupled to both specific recognition and modification of hemimethylated DNA
PA Dumesic, CI Stoddard, S Catania, GJ Narlikar, HD Madhani
Molecular Cell 79 (1), 127-139. e4, 2020
142020
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