Phillip Dumesic
Phillip Dumesic
Dana-Farber Cancer Institute, Damon Runyon Cancer Research Foundation
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Cited by
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Stalled spliceosomes are a signal for RNAi-mediated genome defense
PA Dumesic, P Natarajan, C Chen, IA Drinnenberg, BJ Schiller, ...
Cell 152 (5), 957-968, 2013
Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia
FA Scholl, PA Dumesic, DI Barragan, K Harada, V Bissonauth, J Charron, ...
Developmental cell 12 (4), 615-629, 2007
Product binding enforces the genomic specificity of a yeast polycomb repressive complex
PA Dumesic, CM Homer, JJ Moresco, LR Pack, EK Shanle, SM Coyle, ...
Cell 160 (1), 204-218, 2015
Erk1/2 MAP kinases are required for epidermal G2/M progression
PA Dumesic, FA Scholl, DI Barragan, PA Khavari
Journal of Cell Biology 185 (3), 409-422, 2009
Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase
S Catania, PA Dumesic, H Pimentel, A Nasif, CI Stoddard, JE Burke, ...
Cell 180 (2), 263-277. e20, 2020
Mek1 alters epidermal growth and differentiation
FA Scholl, PA Dumesic, PA Khavari
Cancer research 64 (17), 6035-6040, 2004
Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine
Y Sun, JF Rahbani, MP Jedrychowski, CL Riley, S Vidoni, D Bogoslavski, ...
Nature 593 (7860), 580-585, 2021
Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions
JF Garcia, PA Dumesic, PD Hartley, H El-Samad, HD Madhani
Genes & development 24 (16), 1758-1771, 2010
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia
FA Scholl, PA Dumesic, DI Barragan, K Harada, J Charron, PA Khavari
Cancer research 69 (9), 3772-3778, 2009
Effects of active MEK1 expression in vivo
FA Scholl, PA Dumesic, PA Khavari
Cancer letters 230 (1), 1-5, 2005
An evolutionarily conserved uORF regulates PGC1α and oxidative metabolism in mice, flies, and bluefin tuna
PA Dumesic, DF Egan, P Gut, MT Tran, A Parisi, N Chatterjee, ...
Cell metabolism 30 (1), 190-200. e6, 2019
Ers1 links HP1 to RNAi
M Rougemaille, S Braun, S Coyle, PA Dumesic, JF Garcia, RS Isaac, ...
Proceedings of the National Academy of Sciences 109 (28), 11258-11263, 2012
SnapShot: Regulation and biology of PGC-1α
PR Jannig, PA Dumesic, BM Spiegelman, JL Ruas
Cell 185 (8), 1444-1444. e1, 2022
Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and …
SC Clarke, PA Dumesic, CM Homer, AJ O’Donoghue, F La Greca, ...
PLoS pathogens 12 (12), e1006051, 2016
Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin
FA Scholl, PA Dumesic, DI Barragan, J Charron, PA Khavari
Oncogene 28 (12), 1485-1495, 2009
Recognizing the enemy within: licensing RNA-guided genome defense
PA Dumesic, HD Madhani
Trends in biochemical sciences 39 (1), 25-34, 2014
Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
MJ Mittenbühler, MP Jedrychowski, JG Van Vranken, HG Sprenger, ...
Cell Metabolism 35 (3), 535-549. e7, 2023
Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal …
KL Leung, S Sanchita, CT Pham, BA Davis, M Okhovat, X Ding, ...
Clinical epigenetics 12, 1-16, 2020
The spliceosome as a transposon sensor
PA Dumesic, HD Madhani
RNA biology 10 (11), 1653-1660, 2013
ATP hydrolysis by the SNF2 domain of Dnmt5 is coupled to both specific recognition and modification of hemimethylated DNA
PA Dumesic, CI Stoddard, S Catania, GJ Narlikar, HD Madhani
Molecular Cell 79 (1), 127-139. e4, 2020
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