| Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs LP Lim, NC Lau, P Garrett-Engele, A Grimson, JM Schelter, J Castle, ... Nature 433 (7027), 769-773, 2005 | 5929 | 2005 |
| Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays JM Johnson, J Castle, P Garrett-Engele, Z Kan, PM Loerch, CD Armour, ... Science 302 (5653), 2141-2144, 2003 | 1815 | 2003 |
| Mutant MHC class II epitopes drive therapeutic immune responses to cancer S Kreiter, M Vormehr, N Van de Roemer, M Diken, M Löwer, J Diekmann, ... Nature 520 (7549), 692-696, 2015 | 1215 | 2015 |
| An integrative genomics approach to infer causal associations between gene expression and disease EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ... Nature genetics 37 (7), 710-717, 2005 | 1192 | 2005 |
| Genome-scale RNAi screen for host factors required for HIV replication H Zhou, M Xu, Q Huang, AT Gates, XD Zhang, JC Castle, E Stec, M Ferrer, ... Cell host & microbe 4 (5), 495-504, 2008 | 913 | 2008 |
| Exploiting the mutanome for tumor vaccination JC Castle, S Kreiter, J Diekmann, M Löwer, N Van de Roemer, J de Graaf, ... Cancer research 72 (5), 1081-1091, 2012 | 888 | 2012 |
| Actively personalized vaccination trial for newly diagnosed glioblastoma N Hilf, S Kuttruff-Coqui, K Frenzel, V Bukur, S Stevanović, ... Nature 565 (7738), 240-245, 2019 | 687 | 2019 |
| Experimental annotation of the human genome using microarray technology DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ... Nature 409 (6822), 922-927, 2001 | 614 | 2001 |
| Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2 JI Young, EP Hong, JC Castle, J Crespo-Barreto, AB Bowman, MF Rose, ... Proceedings of the national academy of sciences 102 (49), 17551-17558, 2005 | 538 | 2005 |
| A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart A Kalsotra, X Xiao, AJ Ward, JC Castle, JM Johnson, CB Burge, ... Proceedings of the National Academy of Sciences 105 (51), 20333-20338, 2008 | 535 | 2008 |
| Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma JC Castle, M Loewer, S Boegel, J de Graaf, C Bender, AD Tadmor, ... BMC genomics 15 (1), 1-12, 2014 | 361 | 2014 |
| Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ... Nature genetics 40 (12), 1416-1425, 2008 | 356 | 2008 |
| Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2 C Zhang, Z Zhang, J Castle, S Sun, J Johnson, AR Krainer, MQ Zhang Genes & development 22 (18), 2550-2563, 2008 | 333 | 2008 |
| Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition K Bleasby, JC Castle, CJ Roberts, C Cheng, WJ Bailey, JF Sina, ... Xenobiotica 36 (10-11), 963-988, 2006 | 309 | 2006 |
| HLA typing from RNA-Seq sequence reads S Boegel, M Löwer, M Schäfer, T Bukur, J De Graaf, V Boisguérin, ... Genome medicine 4, 1-12, 2013 | 275 | 2013 |
| Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling X Peng, L Gralinski, CD Armour, MT Ferris, MJ Thomas, S Proll, ... MBio 1 (5), 10.1128/mbio. 00206-10, 2010 | 270 | 2010 |
| Digital transcriptome profiling using selective hexamer priming for cDNA synthesis CD Armour, JC Castle, R Chen, T Babak, P Loerch, S Jackson, JK Shah, ... Nature methods 6 (9), 647-649, 2009 | 237 | 2009 |
| Comparative expression pathway analysis of human and canine mammary tumors P Uva, L Aurisicchio, J Watters, A Loboda, A Kulkarni, J Castle, ... BMC genomics 10 (1), 1-20, 2009 | 195 | 2009 |
| RNA-Seq Atlas—a reference database for gene expression profiling in normal tissue by next-generation sequencing M Krupp, JU Marquardt, U Sahin, PR Galle, J Castle, A Teufel Bioinformatics 28 (8), 1184-1185, 2012 | 183 | 2012 |
| Definition, conservation and epigenetics of housekeeping and tissue-enriched genes X She, CA Rohl, JC Castle, AV Kulkarni, JM Johnson, R Chen BMC genomics 10, 1-12, 2009 | 179 | 2009 |
Jason M. JohnsonDana-Farber Cancer Institute, Stanford, Harvard, Pfizer, Merck, PatientsLikeMeVerified email at dfci.harvard.edu
