Follow
David Malkin
David Malkin
The Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
D Malkin, FP Li, LC Strong, JF Fraumeni Jr, CE Nelson, DH Kim, J Kassel, ...
Science 250 (4985), 1233-1238, 1990
49401990
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226-231, 2012
26292012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
9622012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1), 59-71, 2012
9282012
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
E Bouffet, V Larouche, BB Campbell, D Merico, R De Borja, M Aronson, ...
Journal of clinical oncology 34 (19), 2206-2211, 2016
8312016
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
6962017
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6332014
Medulloblastoma
PA Northcott, GW Robinson, CP Kratz, DJ Mabbott, SL Pomeroy, ...
Nature reviews Disease primers 5 (1), 11, 2019
5202019
Li–Fraumeni syndrome
D Malkin
Adrenocortical Carcinoma: Basic Science and Clinical Concepts, 173-191, 2010
5182010
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma
N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ...
Journal of Clinical Oncology 31 (23), 2927-2935, 2013
5102013
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study
A Villani, A Shore, JD Wasserman, D Stephens, RH Kim, H Druker, ...
The Lancet Oncology 17 (9), 1295-1305, 2016
4762016
Cancer screening recommendations for individuals with Li-Fraumeni syndrome
CP Kratz, MI Achatz, L Brugieres, T Frebourg, JE Garber, MLC Greer, ...
Clinical Cancer Research 23 (11), e38-e45, 2017
4592017
Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms
D Malkin, KW Jolly, N Barbier, AT Look, SH Friend, MC Gebhardt, ...
New England Journal of Medicine 326 (20), 1309-1315, 1992
4471992
Copy number variations and cancer
A Shlien, D Malkin
Genome medicine 1, 1-9, 2009
4362009
Germ-line p53 Mutations Predispose to a Wide Spectrum of Early-onset Cancers
KE Nichols, D Malkin, JE Garber, JF Fraumeni Jr, FP Li
Cancer Epidemiology Biomarkers & Prevention 10 (2), 83-87, 2001
4242001
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ...
Acta neuropathologica 123, 615-626, 2012
4212012
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study
A Villani, U Tabori, J Schiffman, A Shlien, J Beyene, H Druker, ...
The lancet oncology 12 (6), 559-567, 2011
4092011
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
elife 3, e02935, 2014
3972014
Cancer survivorship—genetic susceptibility and second primary cancers: research strategies and recommendations
LB Travis, CS Rabkin, LM Brown, JM Allan, BP Alter, CB Ambrosone, ...
Journal of the National Cancer Institute 98 (1), 15-25, 2006
3932006
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ...
Nature genetics 47 (3), 257-262, 2015
3702015
The system can't perform the operation now. Try again later.
Articles 1–20