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Charles Chuah
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Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
H Kantarjian, NP Shah, A Hochhaus, J Cortes, S Shah, M Ayala, ...
New England Journal of Medicine 362 (24), 2260-2270, 2010
19642010
A phase 2 trial of ponatinib in Philadelphia chromosome–positive leukemias
JE Cortes, DW Kim, J Pinilla-Ibarz, P Le Coutre, R Paquette, C Chuah, ...
New England Journal of Medicine 369 (19), 1783-1796, 2013
12302013
Final 5-year study results of DASISION: the dasatinib versus imatinib study in treatment-naïve chronic myeloid leukemia patients trial
JE Cortes, G Saglio, HM Kantarjian, M Baccarani, J Mayer, C Boqué, ...
Journal of Clinical Oncology 34 (20), 2333, 2016
9622016
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
6622012
Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
JE Cortes, DW Kim, J Pinilla-Ibarz, PD le Coutre, R Paquette, C Chuah, ...
Blood, The Journal of the American Society of Hematology 132 (4), 393-404, 2018
5112018
Bosutinib versus imatinib for newly diagnosed chronic myeloid leukemia: results from the randomized BFORE trial
JE Cortes, C Gambacorti-Passerini, MW Deininger, MJ Mauro, C Chuah, ...
Journal of Clinical Oncology 36 (3), 231, 2018
4812018
Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION)
E Jabbour, HM Kantarjian, G Saglio, JL Steegmann, NP Shah, C Boqué, ...
Blood, The Journal of the American Society of Hematology 123 (4), 494-500, 2014
4712014
Regulation of myeloid leukaemia by the cell-fate determinant Musashi
T Ito, HY Kwon, B Zimdahl, KL Congdon, J Blum, WE Lento, C Zhao, ...
Nature 466 (7307), 765-768, 2010
3982010
BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia
MS Zabriskie, CA Eide, SK Tantravahi, NA Vellore, J Estrada, FE Nicolini, ...
Cancer cell 26 (3), 428-442, 2014
3442014
Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial
JH Lipton, C Chuah, A Guerci-Bresler, G Rosti, D Simpson, S Assouline, ...
The Lancet Oncology 17 (5), 612-621, 2016
2642016
Resistance to imatinib mesylate in chronic myeloid leukaemia
JV Melo, C Chuah
Cancer letters 249 (2), 121-132, 2007
2032007
Phase 2 study of subcutaneous omacetaxine mepesuccinate after TKI failure in patients with chronic-phase CML with T315I mutation
J Cortes, JH Lipton, D Rea, R Digumarti, C Chuah, N Nanda, ...
Blood, The Journal of the American Society of Hematology 120 (13), 2573-2580, 2012
1762012
Chronic myeloid leukemia in Asia
WY Au, PB Caguioa, C Chuah, SC Hsu, S Jootar, DW Kim, IY Kweon, ...
International journal of hematology 89, 14-23, 2009
1612009
Targeting of the MNK–eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function
S Lim, TY Saw, M Zhang, MR Janes, K Nacro, J Hill, AQ Lim, CT Chang, ...
Proceedings of the National Academy of Sciences 110 (25), E2298-E2307, 2013
1562013
Epidemiologic study on survival of chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia patients with BCR-ABL T315I mutation
FE Nicolini, MJ Mauro, G Martinelli, DW Kim, S Soverini, MC Müller, ...
Blood, The Journal of the American Society of Hematology 114 (26), 5271-5278, 2009
1422009
Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia
S Branford, DDH Kim, JF Apperley, CA Eide, S Mustjoki, ST Ong, ...
Leukemia 33 (8), 1835-1850, 2019
1292019
Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial
J Cortes, J Apperley, E Lomaia, B Moiraghi, M Undurraga Sutton, ...
Blood, The Journal of the American Society of Hematology 138 (21), 2042-2050, 2021
1202021
Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia
B Zimdahl, T Ito, A Blevins, J Bajaj, T Konuma, J Weeks, CS Koechlein, ...
Nature genetics 46 (3), 245-252, 2014
1172014
Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome‐positive leukemias with the T315I mutation
FE Nicolini, GW Basak, DW Kim, E Olavarria, J Pinilla‐Ibarz, JF Apperley, ...
Cancer 123 (15), 2875-2880, 2017
1132017
CD98-mediated adhesive signaling enables the establishment and propagation of acute myelogenous leukemia
J Bajaj, T Konuma, NK Lytle, HY Kwon, JN Ablack, JM Cantor, D Rizzieri, ...
Cancer cell 30 (5), 792-805, 2016
1052016
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