Kelly Kersten
Kelly Kersten
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Understanding the tumor immune microenvironment (TIME) for effective therapy
M Binnewies, EW Roberts, K Kersten, V Chan, DF Fearon, M Merad, ...
Nature medicine 24 (5), 541-550, 2018
IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
SB Coffelt, K Kersten, CW Doornebal, J Weiden, K Vrijland, CS Hau, ...
Nature 522 (7556), 345-348, 2015
Genetically engineered mouse models in oncology research and cancer medicine
K Kersten, KE de Visser, MH van Miltenburg, J Jonkers
EMBO molecular medicine 9 (2), 137-153, 2017
Unleashing type-2 dendritic cells to drive protective antitumor CD4+ T cell immunity
M Binnewies, AM Mujal, JL Pollack, AJ Combes, EA Hardison, KC Barry, ...
Cell 177 (3), 556-571. e16, 2019
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response
C Salvagno, M Ciampricotti, S Tuit, CS Hau, A van Weverwijk, SB Coffelt, ...
Nature cell biology 21 (4), 511-521, 2019
An expanded universe of cancer targets
WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ...
Cell 184 (5), 1142-1155, 2021
Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival
M Sobral-Leite, K Van de Vijver, M Michaut, R van der Linden, ...
Oncoimmunology 7 (12), e1509820, 2018
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages
K Kersten, SB Coffelt, M Hoogstraat, NJM Verstegen, K Vrijland, ...
Oncoimmunology 6 (8), e1334744, 2017
Adaptive immune regulation of mammary postnatal organogenesis
V Plaks, B Boldajipour, JR Linnemann, NH Nguyen, K Kersten, Y Wolf, ...
Developmental cell 34 (5), 493-504, 2015
Exploiting the immunomodulatory properties of chemotherapeutic drugs to improve the success of cancer immunotherapy
K Kersten, C Salvagno, KE De Visser
Frontiers in immunology 6, 516, 2015
ZipSeq: barcoding for real-time mapping of single cell transcriptomes
KH Hu, JP Eichorst, CS McGinnis, DM Patterson, ED Chow, K Kersten, ...
Nature methods 17 (8), 833-843, 2020
Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
K Kersten, KH Hu, AJ Combes, B Samad, T Harwin, A Ray, AA Rao, E Cai, ...
Cancer Cell 40 (6), 624-638. e9, 2022
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system
S Klarenbeek, CW Doornebal, SM Kas, N Bonzanni, J Bhin, ...
Oncoimmunology 9 (1), 1724049, 2020
LBA10 Critical role of eosinophils during response to immune checkpoint blockade in breast cancer and other cancer types
L Voorwerk, H Garner, OS Blomberg, L Spagnuolo, M Chalabi, E van Dyk, ...
Annals of Oncology 31, S1142, 2020
MYC promotes immune-suppression in TNBC via inhibition of IFN signaling
D Zimmerli, CS Brambillasca, F Talens, J Bhin, A Bhattacharya, ...
bioRxiv, 2021.02. 24.432659, 2021
MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
D Zimmerli, CS Brambillasca, F Talens, J Bhin, R Linstra, L Romanens, ...
Nature communications 13 (1), 6579, 2022
IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
OS Blomberg, L Spagnuolo, H Garner, L Voorwerk, OI Isaeva, E van Dyk, ...
Cancer Cell 41 (1), 106-123. e10, 2023
Myeloid mechano-metabolic programming restricts anti-tumor immunity
KM Tharp, K Kersten, OM Maller, GA Timblin, C Stashko, FP Canale, ...
bioRxiv, 2022.07. 14.499764, 2022
Predicting breast cancer metastasis; formation of the pre-metastatic niche.
K Kersten
Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung.
K Kersten, R You, S Liang, K Tharp, J Pollack, VM Weaver, MF Krummel, ...
bioRxiv, 2022.11. 15.516217, 2022
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