| Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1090 | 2021 |
| Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins J Martinez, RK Malireddi, Q Lu, LD Cunha, S Pelletier, S Gingras, ... Nature cell biology 17 (7), 893-906, 2015 | 816* | 2015 |
| Caspases in cell death, inflammation, and gasdermin-induced pyroptosis S Kesavardhana, RKS Malireddi, TD Kanneganti Annual review of immunology 38, 567, 2020 | 560 | 2020 |
| ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways T Kuriakose, SM Man, RK Subbarao Malireddi, R Karki, S Kesavardhana, ... Science immunology 1 (2), aag2045-aag2045, 2016 | 544 | 2016 |
| FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes P Gurung, PK Anand, RKS Malireddi, LV Walle, N Van Opdenbosch, ... The Journal of Immunology 192 (4), 1835-1846, 2014 | 532 | 2014 |
| NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens PK Anand, RK Malireddi, JR Lukens, P Vogel, J Bertin, M Lamkanfi, ... Nature 488 (7411), 389-393, 2012 | 430 | 2012 |
| The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis MH Zaki, P Vogel, RK Malireddi, M Body-Malapel, PK Anand, J Bertin, ... Cancer cell 20 (5), 649-660, 2011 | 421 | 2011 |
| The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection SM Man, R Karki, RK Malireddi, G Neale, P Vogel, M Yamamoto, ... Nature immunology 16 (5), 467-475, 2015 | 345 | 2015 |
| Engagement of fatty acids with toll‐like receptor 2 drives interleukin‐1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal–induced gouty arthritis LAB Joosten, MG Netea, E Mylona, MI Koenders, RKS Malireddi, ... Arthritis & Rheumatism 62 (11), 3237-3248, 2010 | 325 | 2010 |
| The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation A Di, S Xiong, Z Ye, RKS Malireddi, S Kometani, M Zhong, M Mittal, ... Immunity 49 (1), 56-65. e4, 2018 | 318 | 2018 |
| Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer SM Man, Q Zhu, L Zhu, Z Liu, R Karki, A Malik, D Sharma, L Li, ... Cell 162 (1), 45-58, 2015 | 309 | 2015 |
| Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation J Wagener, RKS Malireddi, MD Lenardon, M Köberle, S Vautier, ... PLoS pathogens 10 (4), e1004050, 2014 | 280 | 2014 |
| IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes SM Man, R Karki, M Sasai, DE Place, S Kesavardhana, J Temirov, ... Cell 167 (2), 382-396. e17, 2016 | 279 | 2016 |
| Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4 … P Gurung, RKS Malireddi, PK Anand, D Demon, LV Walle, Z Liu, P Vogel, ... Journal of Biological Chemistry 287 (41), 34474-34483, 2012 | 270 | 2012 |
| ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis) RK Malireddi, S Kesavardhana, TD Kanneganti Frontiers in Cellular and Infection Microbiology 9, 406, 2019 | 268 | 2019 |
| Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection R Karki, SM Man, RKS Malireddi, P Gurung, P Vogel, M Lamkanfi, ... Cell host & microbe 17 (3), 357-368, 2015 | 262 | 2015 |
| Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis) S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ... Frontiers in cellular and infection microbiology 10, 237, 2020 | 260 | 2020 |
| The PANoptosome: A deadly protein complex driving pyroptosis, apoptosis, and necroptosis (PANoptosis) P Samir, RK Malireddi, TD Kanneganti Frontiers in Cellular and Infection Microbiology 10, 238, 2020 | 241 | 2020 |
| Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease RK Malireddi, P Gurung, S Kesavardhana, P Samir, A Burton, ... Journal of Experimental Medicine 217 (3), 2020 | 208 | 2020 |
| TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation RKS Malireddi, P Gurung, J Mavuluri, TK Dasari, JM Klco, H Chi, ... Journal of Experimental Medicine 215 (4), 1023-1034, 2018 | 186 | 2018 |
