Jessica Fioravanti
Jessica Fioravanti
Senior Scientist
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Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
C Yao, HW Sun, NE Lacey, Y Ji, EA Moseman, HY Shih, EF Heuston, ...
Nature immunology 20 (7), 890-901, 2019
Immunosurveillance of the liver by intravascular effector CD8+ T cells
LG Guidotti, D Inverso, L Sironi, P Di Lucia, J Fioravanti, L Ganzer, ...
Cell 161 (3), 486-500, 2015
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity
D Hermans, S Gautam, JC García-Cañaveras, D Gromer, S Mitra, ...
Proceedings of the National Academy of Sciences 117 (11), 6047-6055, 2020
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy
TN Yamamoto, PH Lee, SK Vodnala, D Gurusamy, RJ Kishton, Z Yu, ...
The Journal of clinical investigation 129 (4), 1551-1565, 2019
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity
S Gautam, J Fioravanti, W Zhu, JB Le Gall, P Brohawn, NE Lacey, J Hu, ...
Nature immunology 20 (3), 337-349, 2019
Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells
J Medina-Echeverz, J Fioravanti, M Zabala, N Ardaiz, J Prieto, ...
The Journal of Immunology 186 (2), 807-815, 2011
Inflammatory monocytes hinder antiviral B cell responses
S Sammicheli, M Kuka, P Di Lucia, NJ de Oya, M De Giovanni, ...
Science Immunology 1 (4), eaah6789, 2016
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate
Y Ji, J Fioravanti, W Zhu, H Wang, T Wu, J Hu, NE Lacey, S Gautam, ...
Nature communications 10 (1), 2157, 2019
Effector CD8+ T cell-derived interleukin-10 enhances acute liver immunopathology
J Fioravanti, P Di Lucia, D Magini, F Moalli, C Boni, AP Benechet, ...
Journal of hepatology 67 (3), 543-548, 2017
Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin
C Mansilla, P Berraondo, M Durantez, M Martínez, N Casares, ...
International Journal of Cancer 131 (3), 641-651, 2012
Anchoring interferon alpha to apolipoprotein A‐I reduces hematological toxicity while enhancing immunostimulatory properties
J Fioravanti, I González, J Medina‐Echeverz, E Larrea, N Ardaiz, ...
Hepatology 53 (6), 1864-1873, 2011
Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein
MC Ochoa, J Fioravanti, I Rodriguez, S Hervas-Stubbs, A Azpilikueta, ...
Cancer research 73 (1), 139-149, 2013
The fusion protein of IFN-α and apolipoprotein AI crosses the blood–brain barrier by a saturable transport mechanism
J Fioravanti, J Medina-Echeverz, N Ardaiz, C Gomar, ZP Parra-Guillén, ...
The Journal of Immunology 188 (8), 3988-3992, 2012
A Semliki forest virus vector engineered to express IFNα induces efficient elimination of established tumors
JI Quetglas, J Fioravanti, N Ardaiz, J Medina-Echeverz, I Baraibar, J Prieto, ...
Gene therapy 19 (3), 271-278, 2012
Scavenger receptor class B, type I: a promising immunotherapy target
J Fioravanti, J Medina-Echeverz, P Berraondo
Immunotherapy 3 (3), 395-406, 2011
Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein AI
P Berraondo, M Di Scala, K Korolowicz, LM Thampi, I Otano, L Suarez, ...
Journal of hepatology 63 (2), 329-336, 2015
Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy
MC Ochoa, J Fioravanti, EH Duitman, J Medina-Echeverz, A Palazon, ...
PLoS One 7 (12), e52370, 2012
Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases
J Medina-Echeverz, J Fioravanti, N Díaz-Valdés, K Frank, F Aranda, ...
PLoS One 9 (5), e96799, 2014
Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens
N Jiménez de Oya, M De Giovanni, J Fioravanti, R Übelhart, P Di Lucia, ...
EMBO molecular medicine 9 (11), 1482-1490, 2017
Interferon alpha bioactivity critically depends on Scavenger receptor class B type I function
M Vasquez, J Fioravanti, F Aranda, V Paredes, C Gomar, N Ardaiz, ...
Oncoimmunology 5 (8), e1196309, 2016
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