Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels R Shawahna, Y Uchida, X Decleves, S Ohtsuki, S Yousif, S Dauchy, ... Molecular pharmaceutics 8 (4), 1332-1341, 2011 | 394 | 2011 |
ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood–brain barrier S Dauchy, F Dutheil, RJ Weaver, F Chassoux, C Daumas‐Duport, ... Journal of neurochemistry 107 (6), 1518-1528, 2008 | 371 | 2008 |
Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 … S Ohtsuki, C Ikeda, Y Uchida, Y Sakamoto, F Miller, F Glacial, X Decleves, ... Molecular pharmaceutics 10 (1), 289-296, 2013 | 232 | 2013 |
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells S Dauchy, F Miller, PO Couraud, RJ Weaver, B Weksler, IA Romero, ... Biochemical pharmacology 77 (5), 897-909, 2009 | 221 | 2009 |
A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters N Perrière, S Yousif, S Cazaubon, N Chaverot, F Bourasset, S Cisternino, ... Brain research 1150, 1-13, 2007 | 198 | 2007 |
Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function F Dutheil, S Dauchy, M Diry, V Sazdovitch, O Cloarec, L Mellottée, ... Drug Metabolism and Disposition 37 (7), 1528-1538, 2009 | 197 | 2009 |
Functional expression of p‐glycoprotein and multidrug resistance‐associated protein (mrp1) in primary cultures of rat astrocytes X Decleves, A Regina, JL Laplanche, F Roux, B Boval, JM Launay, ... Journal of neuroscience research 60 (5), 594-601, 2000 | 193 | 2000 |
Expression of drug transporters at the blood–brain barrier using an optimized isolated rat brain microvessel strategy S Yousif, C Marie-Claire, F Roux, JM Scherrmann, X Declèves Brain research 1134, 1-11, 2007 | 158 | 2007 |
Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) N Tournier, L Chevillard, B Megarbane, S Pirnay, JM Scherrmann, ... International Journal of Neuropsychopharmacology 13 (7), 905-915, 2010 | 148 | 2010 |
Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface AC Boulay, B Saubaméa, N Adam, S Chasseigneaux, N Mazaré, A Gilbert, ... Cell discovery 3 (1), 1-20, 2017 | 146 | 2017 |
Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice LH Reddy, H Khoury, A Paci, A Deroussent, H Ferreira, C Dubernet, ... Drug Metabolism and Disposition 36 (8), 1570-1577, 2008 | 110 | 2008 |
Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass A Bruyere, X Decleves, F Bouzom, K Ball, C Marques, X Treton, M Pocard, ... Molecular pharmaceutics 7 (5), 1596-1607, 2010 | 107 | 2010 |
Molecular and functional MDR1‐Pgp and MRPs expression in human glioblastoma multiforme cell lines X Declèves, A Fajac, J Lehmann‐Che, M Tardy, C Mercier, I Hurbain, ... International journal of cancer 98 (2), 173-180, 2002 | 106 | 2002 |
ABC transporters at the blood–brain interfaces, their study models, and drug delivery implications in gliomas D Gomez-Zepeda, M Taghi, JM Scherrmann, X Decleves, MC Menet Pharmaceutics 12 (1), 20, 2019 | 103 | 2019 |
Opioids and the blood-brain barrier: a dynamic interaction with consequences on drug disposition in brain C Chaves, F Remiao, S Cisternino, X Decleves Current neuropharmacology 15 (8), 1156-1173, 2017 | 101 | 2017 |
Validity of leg-to-leg bioelectrical impedance analysis to estimate body fat in obesity C Lloret Linares, C Ciangura, JL Bouillot, M Coupaye, X Declèves, ... Obesity Surgery 21, 917-923, 2011 | 98 | 2011 |
Multidrug resistance-associated protein MRP1 expression in human gliomas: chemosensitization to vincristine and etoposide by indomethacin in human glioma cell lines … B Benyahia, S Huguet, X Decleves, K Mokhtari, E Criniere, JF Bernaudin, ... Journal of neuro-oncology 66, 65-70, 2004 | 98 | 2004 |
Purification of mouse brain vessels AC Boulay, B Saubaméa, X Declèves, M Cohen-Salmon JoVE (Journal of Visualized Experiments), e53208, 2015 | 97 | 2015 |
Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier X Decleves, A Jacob, S Yousif, R Shawahna, S Potin, JM Scherrmann Current drug metabolism 12 (8), 732-741, 2011 | 96 | 2011 |
Pharmacology of morphine in obese patients: clinical implications CL Linares, X Decleves, JM Oppert, A Basdevant, K Clement, C Bardin, ... Clinical pharmacokinetics 48, 635-651, 2009 | 96 | 2009 |