Leticia Costa-Lotufo

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Manoel Odorico de Moraes FilhoProfessor Titular da Universidade Federal do CearáVerified email at ufc.br
Paula C. JimenezUniversidade Federal de São PauloVerified email at unifesp.br
Norberto Peporine LopesProfessor de Química Orgânica, FCFRP, Universidade de São PauloVerified email at fcfrp.usp.br
Daniel P. BezerraOswaldo Cruz Foudantion, BrazilVerified email at fiocruz.br
Mary Anne Sousa LimaProfessor de Química Organica, Depto. de Química Orgânica e Inorgânica, Universidade Federal doVerified email at dqoi.ufc.br
Paulo Michel Pinheiro FerreiraUniversidade Federal do PiauíVerified email at ufpi.edu.br
Tito Monteiro da Cruz LotufoAssociate Professor, Instituto Oceanográfico, Universidade de São PauloVerified email at usp.br
Marne Carvalho de VasconcellosProfessora, Universidade Federal do AmazonasVerified email at ufam.edu.br
Vitor Francisco FerreiraProfessor Titular em Química Orgânica da Universidade Federal FluminenseVerified email at id.uff.br
Marilia Oliveira Fonseca GoulartProfessor Titular Livre, Universidade Federal de AlagoasVerified email at qui.ufal.br
Denis AbessaUniversidade Estadual PaulistaVerified email at clp.unesp.br
Jim La ClairXenobe Research Institute, UC San DiegoVerified email at ucsd.edu
Rommel Mario Rodríguez BurbanoInstituto de Ciências Biológicas, Universidade Federal do ParáVerified email at ufpa.br
Monica Tallarico PupoFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, BrazilVerified email at fcfrp.usp.br
Francisco Washington Araújo Barros...Professor do Instituto de Ciências da Saúde da UNILABVerified email at unilab.edu.br
Vanderlan da Silva BolzaniProfessora de Química, Universidade Estadual PaulistaVerified email at iq.unesp.br
Adrian Martin PohlitInstituto Nacional de Pesquisas da AmazoniaVerified email at inpa.gov.br
Alberto Jose CavalheiroInstituto de Química - UNESPVerified email at unesp.br
Dinara Jaqueline MouraProfessor de Toxicologia, Universidade Federal de Ciências da Saúde de Porto AlegreVerified email at ufcspa.edu.br
Jenifer SaffiBiochemistry Professor/ Vice-Rector - UFCSPAVerified email at ufcspa.edu.br

Leticia Costa-Lotufo

Universidade de São Paulo

Verified email at usp.br

Marine Natural Products Anticancer drug discovery and development ecotoxicology


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Studies of the anticancer potential of plants used in Bangladeshi folk medicine LV Costa-Lotufo, MTH Khan, A Ather, DV Wilke, PC Jimenez, C Pessoa, ... Journal of ethnopharmacology 99 (1), 21-30, 2005	375	2005
Overview of the therapeutic potential of piplartine (piperlongumine) DP Bezerra, C Pessoa, MO De Moraes, N Saker-Neto, ER Silveira, ... European Journal of Pharmaceutical Sciences 48 (3), 453-463, 2013	363	2013
Mass spectrometry-based metabolomics in microbiome investigations A Bauermeister, H Mannochio-Russo, LV Costa-Lotufo, AK Jarmusch, ... Nature Reviews Microbiology 20 (3), 143-160, 2022	309	2022
In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper DP Bezerra, FO Castro, A Alves, C Pessoa, MO Moraes, ER Silveira, ... Brazilian journal of medical and biological research 39, 801-807, 2006	269	2006
Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines ML de Mesquita, JE de Paula, C Pessoa, MO de Moraes, LV Costa-Lotufo, ... Journal of ethnopharmacology 123 (3), 439-445, 2009	252	2009
The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin LV Costa-Lotufo, GMA Cunha, PAM Farias, GSB Viana, KMA Cunha, ... Toxicon 40 (8), 1231-1234, 2002	229	2002
Antitumor properties of a sulfated polysaccharide from the red seaweed Champia feldmannii (Diaz‐Pifferer) KOAL Lins, DP Bezerra, APNN Alves, NMN Alencar, MW Lima, VM Torres, ... Journal of Applied Toxicology 29 (1), 20-26, 2009	190	2009
In vitro and in vivo antitumor effect of 5‐FU combined with piplartine and piperine DP Bezerra, FO Castro, APNN Alves, C Pessoa, MO Moraes, ER Silveira, ... Journal of Applied Toxicology: An International Journal 28 (2), 156-163, 2008	185	2008
Piplartine induces inhibition of leukemia cell proliferation triggering both apoptosis and necrosis pathways DP Bezerra, GCG Militão, FO De Castro, C Pessoa, MO De Moraes, ... Toxicology in vitro 21 (1), 1-8, 2007	148	2007
Genotoxicity evaluation of kaurenoic acid, a bioactive diterpenoid present in Copaiba oil BC Cavalcanti, LV Costa-Lotufo, MO Moraes, RR Burbano, ER Silveira, ... Food and chemical toxicology 44 (3), 388-392, 2006	146	2006
Contamination of port zone sediments by metals from Large Marine Ecosystems of Brazil LM Buruaem, MA Hortellani, JE Sarkis, LV Costa-Lotufo, DMS Abessa Marine pollution bulletin 64 (3), 479-488, 2012	145	2012
Folk uses and pharmacological properties of Casearia sylvestris: a medicinal review PMP Ferreira, LV Costa-Lotufo, MO Moraes, FWA Barros, A Martins, ... Anais da Academia Brasileira de Ciências 83, 1373-1384, 2011	139	2011
The floating Sargassum (Phaeophyceae) of the South Atlantic Ocean – likely scenarios MN Sissini, MBB de Barros Barreto, MTM Széchy, MB De Lucena, ... Phycologia 56 (3), 321-328, 2017	133	2017
In vivo growth-inhibition of Sarcoma 180 tumor by alginates from brown seaweed Sargassum vulgare APA de Sousa, MR Torres, C Pessoa, MO de Moraes, FD Rocha Filho, ... Carbohydrate polymers 69 (1), 7-13, 2007	133	2007
Enriching cancer pharmacology with drugs of marine origin PC Jimenez, DV Wilke, PC Branco, A Bauermeister, P Rezende‐Teixeira, ... British Journal of Pharmacology 177 (1), 3-27, 2020	129	2020
Biological activity in extracts of ascidians (Tunicata, Ascidiacea) from the northeastern Brazilian coast PC Jimenez, SC Fortier, TMC Lotufo, C Pessoa, MEA Moraes, ... Journal of Experimental Marine Biology and Ecology 287 (1), 93-101, 2003	124	2003
Genotoxic effects of aluminum chloride in cultured human lymphocytes treated in different phases of cell cycle PDL Lima, DS Leite, MC Vasconcellos, BC Cavalcanti, RA Santos, ... Food and Chemical Toxicology 45 (7), 1154-1159, 2007	123	2007
What can we learn from commercial insecticides? Efficacy, toxicity, environmental impacts, and future developments P Rezende-Teixeira, RG Dusi, PC Jimenez, LS Espindola, ... Environmental Pollution 300, 118983, 2022	117	2022
A community resource for paired genomic and metabolomic data mining MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ... Nature Chemical Biology 17 (4), 363-368, 2021	117	2021
A contribuição dos produtos naturais como fonte de novos fármacos anticâncer: estudos no Laboratório Nacional de Oncologia Experimental da Universidade Federal do Ceará LV Costa-Lotufo, RC Montenegro, APNN Alves, SVF Madeira, C Pessoa, ... Revista Virtual de Química 2 (1), 47-58, 2010	116	2010

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