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Sonia Chothani
Sonia Chothani
Research Fellow, Duke-NUS school of medicine
Verified email at u.duke.nus.edu - Homepage
Title
Cited by
Cited by
Year
IL-11 is a crucial determinant of cardiovascular fibrosis
S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ...
Nature 552 (7683), 110-115, 2017
5262017
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ...
Science translational medicine 11 (511), eaaw1237, 2019
2162019
Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis
AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ...
Gastroenterology 157 (3), 777-792. e14, 2019
2102019
Characterising the loss-of-function impact of 5’untranslated region variants in 15,708 individuals
N Whiffin, KJ Karczewski, X Zhang, S Chothani, MJ Smith, DG Evans, ...
Nature communications 11 (1), 2523, 2020
1312020
Widespread translational control of fibrosis in the human heart by RNA-binding proteins
S Chothani, S Schäfer, E Adami, S Viswanathan, AA Widjaja, SR Langley, ...
Circulation 140 (11), 937-951, 2019
962019
deltaTE: detection of translationally regulated genes by integrative analysis of Ribo‐seq and RNA‐seq Data
S Chothani, E Adami, JF Ouyang, S Viswanathan, N Hubner, SA Cook, ...
Current protocols in molecular biology 129 (1), e108, 2019
862019
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ...
Nature communications 12 (1), 66, 2021
832021
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity
CQE Lee, B Kerouanton, S Chothani, S Zhang, Y Chen, CK Mantri, ...
Nature communications 12 (1), 2130, 2021
662021
Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease
B Ng, J Dong, S Viswanathan, AA Widjaja, BS Paleja, E Adami, NSJ Ko, ...
The FASEB Journal 34 (9), 11802-11815, 2020
482020
A high-resolution map of human RNA translation
SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ...
Molecular cell 82 (15), 2885-2899. e8, 2022
472022
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ...
Science Translational Medicine 13 (597), eaba8146, 2021
452021
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
E Adami, S Viswanathan, AA Widjaja, B Ng, S Chothani, N Zhihao, J Tan, ...
Rheumatology 60 (12), 5820-5826, 2021
392021
Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy
AA Widjaja, SP Chothani, SA Cook
Human Vaccines & Immunotherapeutics 16 (10), 2357-2362, 2020
372020
LASER server: ancestry tracing with genotypes or sequence reads
D Taliun, SP Chothani, S Schönherr, L Forer, M Boehnke, GR Abecasis, ...
Bioinformatics 33 (13), 2056-2058, 2017
362017
IL11 stimulates IL33 expression and proinflammatory fibroblast activation across tissues
AA Widjaja, S Chothani, S Viswanathan, JWT Goh, WW Lim, SA Cook
International Journal of Molecular Sciences 23 (16), 8900, 2022
282022
Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis
B Ng, AA Widjaja, S Viswanathan, J Dong, SP Chothani, S Lim, ...
Scientific Reports 11 (1), 14088, 2021
282021
Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo
J Zhou, B Ng, NSJ Ko, LR Fiedler, E Khin, A Lim, NE Sahib, Y Wu, ...
Human molecular genetics 28 (12), 1971-1981, 2019
272019
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
AA Widjaja, S Viswanathan, SG Shekeran, E Adami, WW Lim, S Chothani, ...
Nature Communications 13 (1), 7497, 2022
152022
Structure based approach for understanding organism specific recognition of protein-RNA complexes
R Nagarajan, SP Chothani, C Ramakrishnan, M Sekijima, MM Gromiha
Biology Direct 10, 1-13, 2015
152015
Whole-genome sequencing of Finnish type 1 diabetic siblings discordant for kidney disease reveals DNA variants associated with diabetic nephropathy
J Guo, OJL Rackham, N Sandholm, B He, AM Österholm, E Valo, ...
Journal of the American Society of Nephrology 31 (2), 309-323, 2020
132020
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