Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane NZ Gerges, DS Backos, CN Rupasinghe, MR Spaller, JA Esteban The EMBO journal 25 (8), 1623-1634, 2006 | 185 | 2006 |
Rapid activation of CLOCK by Ca2+‐dependent protein kinase C mediates resetting of the mammalian circadian clock HS Shim, H Kim, J Lee, GH Son, S Cho, TH Oh, SH Kang, DS Seen, ... EMBO reports 8 (4), 366-371, 2007 | 105 | 2007 |
A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95 D Saro, T Li, C Rupasinghe, A Paredes, N Caspers, MR Spaller Biochemistry 46 (21), 6340-6352, 2007 | 96 | 2007 |
Inhibition of N-methyl-D-aspartate-induced retinal neuronal death by polyarginine peptides is linked to the attenuation of stress-induced hyperpolarization of the inner … J Marshall, KY Wong, CN Rupasinghe, R Tiwari, X Zhao, ED Berberoglu, ... Journal of Biological Chemistry 290 (36), 22030-22048, 2015 | 58 | 2015 |
Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer CR Patra, CN Rupasinghe, SK Dutta, S Bhattacharya, E Wang, ... ACS Chemical Biology 7 (4), 770-779, 2012 | 51 | 2012 |
A cyclic peptide targeted against PSD-95 blocks central sensitization and attenuates thermal hyperalgesia BW LeBlanc, M Iwata, AP Mallon, CN Rupasinghe, DJ Goebel, J Marshall, ... Neuroscience 167 (2), 490-500, 2010 | 44 | 2010 |
T7 phage display as a method of peptide ligand discovery for PDZ domain proteins SC Sharma, A Memic, CN Rupasinghe, ACE Duc, MR Spaller Peptide Science: Original Research on Biomolecules 92 (3), 183-193, 2009 | 41 | 2009 |
RGS-GAIP–interacting protein controls breast cancer progression L Wang, JS Lau, CR Patra, Y Cao, S Bhattacharya, S Dutta, D Nandy, ... Molecular Cancer Research 8 (12), 1591-1600, 2010 | 32 | 2010 |
A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death O Bucur, G Gaidos, A Yatawara, B Pennarun, C Rupasinghe, J Roux, ... Scientific reports 5 (1), 9893, 2015 | 31 | 2015 |
Design, synthesis, and evaluation of linear and cyclic peptide ligands for PDZ10 of the multi-PDZ domain protein MUPP1 SC Sharma, CN Rupasinghe, RB Parisien, MR Spaller Biochemistry 46 (44), 12709-12720, 2007 | 26 | 2007 |
The interplay between structure-based design and combinatorial chemistry CN Rupasinghe, MR Spaller Current opinion in chemical biology 10 (3), 188-193, 2006 | 26 | 2006 |
Targeting receptor tyrosine kinases and their downstream signaling with cell‐penetrating peptides in human pulmonary artery smooth muscle and endothelial cells J Yu, C Rupasinghe, JL Wilson, L Taylor, N Rahimi, D Mierke, P Polgar Chemical biology & drug design 85 (5), 586-597, 2015 | 19 | 2015 |
A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model DS Green, C Rupasinghe, R Warburton, JL Wilson, CO Sallum, L Taylor, ... PLoS One 8 (11), e81309, 2013 | 18 | 2013 |
killerFLIP: a novel lytic peptide specifically inducing cancer cell death B Pennarun, G Gaidos, O Bucur, A Tinari, C Rupasinghe, T Jin, R Dewar, ... Cell Death & Disease 4 (10), e894-e894, 2013 | 17 | 2013 |
Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA M Kaur, CN Rupasinghe, E Klosi, MR Spaller, CS Chow Bioorganic & medicinal chemistry 21 (5), 1240-1247, 2013 | 17 | 2013 |
Small‐molecule inhibitors of JC polyomavirus infection A Yatawara, G Gaidos, CN Rupasinghe, BA O'Hara, M Pellegrini, ... Journal of Peptide Science 21 (3), 236-242, 2015 | 11 | 2015 |
Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptides JL Wilson, C Rupasinghe, A Usheva, R Warburton, C Kaplan, L Taylor, ... Current topics in peptide & protein research 16, 1, 2015 | 10 | 2015 |
Gallic acid-based small-molecule inhibitors of JC and BK polyomaviral infection BA O’Hara, C Rupasinghe, A Yatawara, G Gaidos, DF Mierke, WJ Atwood Virus research 189, 280-285, 2014 | 10 | 2014 |
Enhancing and limiting endothelin‐1 signaling with a cell‐penetrating peptide mimicking the third intracellular loop of the ETB receptor CO Sallum, JL Wilson, C Rupasinghe, E Berg, J Yu, DS Green, L Taylor, ... Chemical biology & drug design 80 (3), 374-381, 2012 | 7 | 2012 |
Chemically-modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer D Mukhopadhyay ACS chemical biology 14 (10), 2327, 2015 | 3 | 2015 |