Karolina Mikulska-Ruminska
Karolina Mikulska-Ruminska
Institute of Physics, Nicolaus Copernicus University in Torun, Poland
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PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals
SE Wenzel, YY Tyurina, J Zhao, CMS Croix, HH Dar, G Mao, VA Tyurin, ...
Cell 171 (3), 628-641. e26, 2017
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
AA Kapralov, Q Yang, HH Dar, YY Tyurina, TS Anthonymuthu, R Kim, ...
Nature chemical biology 16 (3), 278-290, 2020
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
WY Sun, VA Tyurin, K Mikulska-Ruminska, IH Shrivastava, ...
Nature chemical biology 17 (4), 465-476, 2021
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium
HH Dar, YY Tyurina, K Mikulska-Ruminska, I Shrivastava, HC Ting, ...
The Journal of clinical investigation 128 (10), 4639-4653, 2019
ProDy 2.0: increased scale and scope after 10 years of protein dynamics modelling with Python
S Zhang, JM Krieger, Y Zhang, C Kaya, B Kaynak, K Mikulska-Ruminska, ...
Bioinformatics 37 (20), 3657-3659, 2021
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis
TS Anthonymuthu, YY Tyurina, WY Sun, K Mikulska-Ruminska, ...
Redox Biology 38, 101744, 2021
Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE
TS Anthonymuthu, EM Kenny, I Shrivastava, YY Tyurina, ZE Hier, HC Ting, ...
Journal of the American Chemical Society 140 (51), 17835-17839, 2018
The repellent DEET potentiates carbamate effects via insect muscarinic receptor interactions: an alternative strategy to control insect vector-borne diseases
A Abd-Ella, M Stankiewicz, K Mikulska, W Nowak, C Pennetier, M Goulu, ...
PloS one 10 (5), e0126406, 2015
Characterization of differential dynamics, specificity, and allostery of lipoxygenase family members
K Mikulska-Ruminska, I Shrivastava, J Krieger, S Zhang, H Li, H Bayır, ...
Journal of chemical information and modeling 59 (5), 2496-2508, 2019
Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation
J Dagvadorj, K Mikulska-Ruminska, G Tumurkhuu, RA Ratsimandresy, ...
Proceedings of the National Academy of Sciences 118 (1), e2015632118, 2021
NO Represses the Oxygenation of Arachidonoyl PE by 15LOX/PEBP1: Mechanism and Role in Ferroptosis
K Mikulska-Ruminska, TS Anthonymuthu, A Levkina, IH Shrivastava, ...
International Journal of Molecular Sciences 22 (10), 5253, 2021
AFM force spectroscopy and steered molecular dynamics simulation of protein contactin 4
J Strzeleckia, K Mikulskaa, M Lekkab, A Kulikc, A Baltera, W Nowaka
proteins 116, 156-159, 2009
Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD
K Mikulska-Ruminska, AJ Kulik, C Benadiba, I Bahar, G Dietler, W Nowak
Scientific reports 7 (1), 8852, 2017
State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps
Y Zhang, J Krieger, K Mikulska-Ruminska, B Kaynak, COS Sorzano, ...
Progress in biophysics and molecular biology 160, 104-120, 2021
Orthosteric muscarinic receptor activation by the insect repellent IR3535 opens new prospects in insecticide-based vector control
E Moreau, K Mikulska-Ruminska, M Goulu, S Perrier, C Deshayes, ...
Scientific reports 10 (1), 6842, 2020
Nanomechanics of new materials—AFM and computer modelling studies of trichoptera silk
J Strzelecki, J Strzelecka, K Mikulska, M Tszydel, A Balter, W Nowak
Open Physics 9 (2), 482-491, 2011
Nanomechanics of β-rich proteins related to neuronal disorders studied by AFM, all-atom and coarse-grained MD methods
K Mikulska, J Strzelecki, W Nowak
Journal of Molecular Modeling 20, 1-10, 2014
Nanomechanics of Ig-like domains of human contactin (BIG-2)
K Mikulska, Ł Pepłowski, W Nowak
Journal of molecular modeling 17, 2313-2323, 2011
Nanomechanical unfolding of α-neurexin-a major component of the synaptic junction
K Mikulska, J Strzelecki, A Balter, W Nowak
Chemical Physics Letters 521, 134-137, 2012
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators
HH Dar, K Mikulska-Ruminska, YY Tyurina, DK Luci, A Yasgar, ...
Proceedings of the National Academy of Sciences 120 (25), e2218896120, 2023
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