Alexandre Prat
Alexandre Prat
CHUM, CRCHUM, Université de Montréal, Faculté de Médecine
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The blood–brain barrier
R Daneman, A Prat
Cold Spring Harbor perspectives in biology 7 (1), a020412, 2015
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
H Kebir, K Kreymborg, I Ifergan, A Dodelet-Devillers, R Cayrol, M Bernard, ...
Nature medicine 13 (10), 1173-1175, 2007
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ...
Nature medicine 22 (6), 586-597, 2016
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
JI Alvarez, A Dodelet-Devillers, H Kebir, I Ifergan, PJ Fabre, S Terouz, ...
Science 334 (6063), 1727-1731, 2011
Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis
H Kebir, I Ifergan, JI Alvarez, M Bernard, J Poirier, N Arbour, P Duquette, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
An updated histological classification system for multiple sclerosis lesions
T Kuhlmann, S Ludwin, A Prat, J Antel, W Brück, H Lassmann
Acta neuropathologica 133, 13-24, 2017
Glial influence on the blood brain barrier
JI Alvarez, T Katayama, A Prat
Glia 61 (12), 1939-1958, 2013
How do immune cells overcome the blood–brain barrier in multiple sclerosis?
C Larochelle, JI Alvarez, A Prat
FEBS letters 585 (23), 3770-3780, 2011
Brain‐immune connection: immuno‐regulatory properties of CNS‐resident cells
B Becher, A Prat, JP Antel
Glia 29 (4), 293-304, 2000
Association of initial disease-modifying therapy with later conversion to secondary progressive multiple sclerosis
JWL Brown, A Coles, D Horakova, E Havrdova, G Izquierdo, A Prat, ...
Jama 321 (2), 175-187, 2019
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
R Cayrol, K Wosik, JL Berard, A Dodelet-Devillers, I Ifergan, H Kebir, ...
Nature immunology 9 (2), 137-145, 2008
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation
L Mayo, SA Trauger, M Blain, M Nadeau, B Patel, JI Alvarez, ...
Nature medicine 20 (10), 1147-1156, 2014
Glial cell influence on the human blood‐brain barrier
A Prat, K Biernacki, K Wosik, JP Antel
Glia 36 (2), 145-155, 2001
Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy
R Li, A Rezk, Y Miyazaki, E Hilgenberg, H Touil, P Shen, CS Moore, ...
Science translational medicine 7 (310), 310ra166-310ra166, 2015
Defining secondary progressive multiple sclerosis
J Lorscheider, K Buzzard, V Jokubaitis, T Spelman, E Havrdova, ...
Brain 139 (9), 2395-2405, 2016
Disruption of central nervous system barriers in multiple sclerosis
JI Alvarez, R Cayrol, A Prat
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (2), 252-264, 2011
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39
MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ...
Nature neuroscience 22 (5), 729-740, 2019
MAFG-driven astrocytes promote CNS inflammation
MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, ...
Nature 578 (7796), 593-599, 2020
Transcriptome analysis reveals nonfoamy rather than foamy plaque macrophages are proinflammatory in atherosclerotic murine models
K Kim, D Shim, JS Lee, K Zaitsev, JW Williams, KW Kim, MY Jang, ...
Circulation research 123 (10), 1127-1142, 2018
Immunologic privilege in the central nervous system and the blood–brain barrier
LL Muldoon, JI Alvarez, DJ Begley, RJ Boado, GJ Del Zoppo, ND Doolittle, ...
Journal of Cerebral Blood Flow & Metabolism 33 (1), 13-21, 2013
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