| Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification S Yoo, DR Mittelstein, RC Hurt, J Lacroix, MG Shapiro Nature communications 13 (1), 493, 2022 | 298 | 2022 |
| A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1 WM Botello-Smith, W Jiang, H Zhang, AD Ozkan, YC Lin, CN Pham, ... Nature communications 10 (1), 4503, 2019 | 208 | 2019 |
| Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1 JJ Lacroix, WM Botello-Smith, Y Luo Nature communications 9 (1), 2029, 2018 | 148 | 2018 |
| A mechanism for the activation of the Na/H exchanger NHE‐1 by cytoplasmic acidification and mitogens J Lacroix, M Poët, C Maehrel, L Counillon EMBO reports 5 (1), 91-96, 2004 | 115 | 2004 |
| Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor JJ Lacroix, F Bezanilla Proceedings of the National Academy of Sciences 108 (16), 6444-6449, 2011 | 86 | 2011 |
| Moving Gating Charges through the Gating Pore in a Kv Channel Voltage-Sensor JJ Lacroix, CH Hyde, FV Campos, F Bezanilla Biophysical Journal 106 (2), 16a, 2014 | 84 | 2014 |
| Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation JJ Lacroix, FV Campos, L Frezza, F Bezanilla Neuron 79 (4), 651-657, 2013 | 72 | 2013 |
| Intermediate state trapping of a voltage sensor JJ Lacroix, SA Pless, L Maragliano, FV Campos, JD Galpin, CA Ahern, ... Journal of General Physiology 140 (6), 635-652, 2012 | 64 | 2012 |
| Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock WM Botello-Smith, A Alsamarah, P Chatterjee, C Xie, JJ Lacroix, J Hao, ... PLoS Computational Biology 13 (8), e1005711, 2017 | 62 | 2017 |
| Kv3.1 uses a timely resurgent K+ current to secure action potential repolarization AJ Labro, MF Priest, JJ Lacroix, DJ Snyders, F Bezanilla Nature communications 6 (1), 10173, 2015 | 62 | 2015 |
| Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential J Lacroix, CR Halaszovich, DN Schreiber, MG Leitner, F Bezanilla, ... Journal of Biological Chemistry 286 (20), 17945-17953, 2011 | 60 | 2011 |
| Can relative binding free energy predict selectivity of reversible covalent inhibitors? P Chatterjee, WM Botello-Smith, H Zhang, L Qian, A Alsamarah, D Kent, ... Journal of the American Chemical Society 139 (49), 17945-17952, 2017 | 53 | 2017 |
| Properties of deactivation gating currents in Shaker channels JJ Lacroix, AJ Labro, F Bezanilla Biophysical journal 100 (5), L28-L30, 2011 | 49 | 2011 |
| Molecular mechanism for depolarization-induced modulation of Kv channel closure AJ Labro, JJ Lacroix, CA Villalba-Galea, DJ Snyders, F Bezanilla Journal of General Physiology 140 (5), 481-493, 2012 | 47 | 2012 |
| Crowding-induced opening of the mechanosensitive Piezo1 channel in silico W Jiang, JS Del Rosario, W Botello-Smith, S Zhao, Y Lin, H Zhang, ... Communications Biology 4 (1), 84, 2021 | 44 | 2021 |
| Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol‐ and caveolin‐rich membrane microdomains X Tekpli, L Huc, J Lacroix, M Rissel, M Poët, J Noël, MT Dimanche‐Boitrel, ... Journal of Cellular Physiology 216 (1), 207-220, 2008 | 40 | 2008 |
| Kinetic Analysis of the Regulation of the Na+/H+ Exchanger NHE-1 by Osmotic Shocks J Lacroix, M Poët, L Huc, V Morello, N Djerbi, M Ragno, M Rissel, X Tekpli, ... Biochemistry 47 (51), 13674-13685, 2008 | 37 | 2008 |
| S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel MF Priest, JJ Lacroix, CA Villalba-Galea, F Bezanilla Biophysical journal 105 (10), 2312-2322, 2013 | 36 | 2013 |
| Mutant SOD1 forms ion channel: implications for ALS pathophysiology MJ Allen, JJ Lacroix, S Ramachandran, R Capone, JL Whitlock, ... Neurobiology of disease 45 (3), 831-838, 2012 | 36 | 2012 |
| Development of a PET radioligand for potassium channels to image CNS demyelination P Brugarolas, JE Sánchez-Rodríguez, HM Tsai, F Basuli, SH Cheng, ... Scientific reports 8 (1), 607, 2018 | 35 | 2018 |
Francisco BezanillaProfessor of Biochemistry and Molecular Biology University of ChicagoVerified email at uchicago.edu
