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Jinwei Zhang
Jinwei Zhang
Principal Investigator, Chinese Academy of Sciences, University of Exeter, Xiamen University
Verified email at sioc.ac.cn
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Cited by
Year
Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus
JK Karimy, J Zhang, DB Kurland, BC Theriault, D Duran, JA Stokum, ...
Nature medicine 23 (8), 997-1003, 2017
2852017
The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters
DR Alessi, J Zhang, A Khanna, T Hochdörfer, Y Shang, KT Kahle
Science signaling 7 (334), re3-re3, 2014
2812014
Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK1‐dependent phosphorylation and activation
A Kazlauskaite, RJ Martínez‐Torres, S Wilkie, A Kumar, J Peltier, ...
EMBO reports 16 (8), 939-954, 2015
2242015
The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl− co-transporters
P de los Heros, DR Alessi, R Gourlay, DG Campbell, M Deak, ...
Biochemical Journal 458 (3), 559-573, 2014
2152014
WNK Kinase Signaling in Ion Homeostasis and Human Disease
M Shekarabi, J Zhang, AR Khanna, DH Ellison, E Delpire, KT Kahle
Cell Metabolism 25 (2), 285-299, 2017
1902017
GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor
AD Reith, P Bamborough, K Jandu, D Andreotti, L Mensah, P Dossang, ...
Bioorganic & medicinal chemistry letters 22 (17), 5625-5629, 2012
1692012
WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons
P Friedel, KT Kahle, J Zhang, N Hertz, LI Pisella, E Buhler, F Schaller, ...
Science signaling 8 (383), ra65-ra65, 2015
1332015
Brain penetrant LRRK2 inhibitor
HG Choi, J Zhang, X Deng, JM Hatcher, MP Patricelli, Z Zhao, DR Alessi, ...
ACS medicinal chemistry letters 3 (8), 658-662, 2012
1322012
Purification and Characterization of a Cold-Adapted α-Amylase Produced by Nocardiopsis sp. 7326 Isolated from Prydz Bay, Antarctic
JW Zhang, RY Zeng
Marine Biotechnology 10, 75-82, 2008
1052008
Characterization of TAE684 as a potent LRRK2 kinase inhibitor
J Zhang, X Deng, HG Choi, DR Alessi, NS Gray
Bioorganic & medicinal chemistry letters 22 (5), 1864-1869, 2012
1022012
Cloning, expression, and characterization of a cold-adapted lipase gene from an Antarctic deep-sea psychrotrophic bacterium, Psychrobacter sp. 7195
J Zhang, S Lin, R Zeng
Journal of microbiology and biotechnology 17 (4), 604-610, 2007
992007
Characterisation of the Cullin‐3 mutation that causes a severe form of familial hypertension and hyperkalaemia
FR Schumacher, K Siew, J Zhang, C Johnson, N Wood, SE Cleary, ...
EMBO Molecular Medicine 7 (10), 1285-1306, 2015
922015
Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity
C Yao, WM Johnson, Y Gao, W Wang, J Zhang, M Deak, DR Alessi, X Zhu, ...
Human molecular genetics 22 (2), 328-344, 2013
902013
GABA A receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl−-sensitive WNK1 kinase
M Heubl, J Zhang, JC Pressey, S Al Awabdh, M Renner, F Gomez-Castro, ...
Nature communications 8 (1), 1-17, 2017
882017
Molecular Cloning and Expression of a Cold-Adapted Lipase Gene from an Antarctic Deep Sea Psychrotrophic Bacterium Pseudomonas sp. 7323
J Zhang, R Zeng
Marine biotechnology 10, 612-621, 2008
852008
Modulation of brain cation-Cl cotransport via the SPAK kinase inhibitor ZT-1a
J Zhang, MIH Bhuiyan, T Zhang, JK Karimy, Z Wu, VM Fiesler, J Zhang, ...
Nature communications 11 (1), 78, 2020
742020
Mutations in chromatin modifier and ephrin signaling genes in vein of Galen malformation
D Duran, X Zeng, SC Jin, J Choi, C Nelson-Williams, B Yatsula, J Gaillard, ...
Neuron 101 (3), 429-443. e4, 2019
692019
Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival
M Watanabe, J Zhang, MS Mansuri, J Duan, JK Karimy, E Delpire, ...
Science signaling 12 (603), eaaw9315, 2019
622019
Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
X Deng, JM Elkins, J Zhang, Q Yang, T Erazo, N Gomez, HG Choi, ...
European journal of medicinal chemistry 70, 758-767, 2013
612013
Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor
JM Hatcher, J Zhang, HG Choi, G Ito, DR Alessi, NS Gray
ACS medicinal chemistry letters 6 (5), 584-589, 2015
592015
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