David M. Virshup
David M. Virshup
Duke-NUS Medical School Singapore
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Cited by
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An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome
KL Toh, CR Jones, Y He, EJ Eide, WA Hinz, DM Virshup, LJ Ptácek, ...
Science 291 (5506), 1040-1043, 2001
Post-translational modifications regulate the ticking of the circadian clock
M Gallego, DM Virshup
Nature reviews Molecular cell biology 8 (2), 139-148, 2007
From promiscuity to precision: protein phosphatases get a makeover
DM Virshup, S Shenolikar
Molecular cell 33 (5), 537-545, 2009
Control of mammalian circadian rhythm by CKIε-regulated proteasome-mediated PER2 degradation
EJ Eide, MF Woolf, H Kang, P Woolf, W Hurst, F Camacho, EL Vielhaber, ...
Molecular and cellular biology 25 (7), 2795-2807, 2005
Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A
JM Seeling, JR Miller, R Gil, RT Moon, R White, DM Virshup
Science 283 (5410), 2089-2091, 1999
The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm
B McCright, AM Rivers, S Audlin, DM Virshup
Journal of Biological Chemistry 271 (36), 22081-22089, 1996
Setting clock speed in mammals: the CK1ɛ tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins
QJ Meng, L Logunova, ES Maywood, M Gallego, J Lebiecki, TM Brown, ...
Neuron 58 (1), 78-88, 2008
Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I ɛ
E Vielhaber, E Eide, A Rivers, ZH Gao, DM Virshup
Molecular and cellular biology 20 (13), 4888-4899, 2000
The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iε
EJ Eide, EL Vielhaber, WA Hinz, DM Virshup
Journal of Biological Chemistry 277 (19), 17248-17254, 2002
Protein phosphatase 2A: a panoply of enzymes
DM Virshup
Current opinion in cell biology 12 (2), 180-185, 2000
Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer
KD Proffitt, B Madan, Z Ke, V Pendharkar, L Ding, MA Lee, RN Hannoush, ...
Cancer research 73 (2), 502-507, 2013
Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts
Z Kabiri, G Greicius, B Madan, S Biechele, Z Zhong, H Zaribafzadeh, ...
Development 141 (11), 2206-2215, 2014
Wnt addiction of genetically defined cancers reversed by PORCN inhibition
B Madan, Z Ke, N Harmston, SY Ho, AO Frois, J Alam, DA Jeyaraj, ...
Oncogene 35 (17), 2197-2207, 2016
Identification of cellular proteins required for simian virus 40 DNA replication
MS Wold, DH Weinberg, DM Virshup, JJ Li, TJ Kelly
Journal of Biological Chemistry 264 (5), 2801-2809, 1989
Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex
ZH Gao, JM Seeling, V Hill, A Yochum, DM Virshup
Proceedings of the National Academy of Sciences 99 (3), 1182-1187, 2002
Identification of a new family of protein phosphatase 2A regulatory subunits (∗)
B McCright, DM Virshup
Journal of Biological Chemistry 270 (44), 26123-26128, 1995
PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
G Greicius, Z Kabiri, K Sigmundsson, C Liang, R Bunte, MK Singh, ...
Proceedings of the National Academy of Sciences 115 (14), E3173-E3181, 2018
Casein kinase 1: Complexity in the family
JK Cheong, DM Virshup
The international journal of biochemistry & cell biology 43 (4), 465-469, 2011
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1
H Okamura, C Garcia-Rodriguez, H Martinson, J Qin, DM Virshup, A Rao
Molecular and cellular biology 24 (10), 4184-4195, 2004
Role for the PP2A/B56δ phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis
SS Margolis, JA Perry, CM Forester, LK Nutt, Y Guo, MJ Jardim, ...
Cell 127 (4), 759-773, 2006
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