Henne Holstege
Henne Holstege
Amsterdam UMC, Alzheimer Center, Clinical Genetics
Verified email at - Homepage
Cited by
Cited by
Alzheimer's disease
P Scheltens, B De Strooper, M Kivipelto, H Holstege, G Chételat, ...
The Lancet 397 (10284), 1577-1590, 2021
Activation of central melanocortin pathways by fenfluramine
LK Heisler, MA Cowley, LH Tecott, W Fan, MJ Low, JL Smart, ...
Science 297 (5581), 609-611, 2002
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer
X Liu, H Holstege, H van der Gulden, M Treur-Mulder, J Zevenhoven, ...
Proceedings of the National Academy of Sciences 104 (29), 12111-12116, 2007
Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin
B Evers, R Drost, E Schut, M de Bruin, E van der Burg, PWB Derksen, ...
Clinical Cancer Research 14 (12), 3916-3925, 2008
BRD7 is a candidate tumour suppressor gene required for p53 function
J Drost, F Mantovani, F Tocco, R Elkon, A Comel, H Holstege, ...
Nature cell biology 12 (4), 380-389, 2010
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer
H Holstege, SA Joosse, CTM van Oostrom, PM Nederlof, A de Vries, ...
Cancer research 69 (8), 3625-3633, 2009
Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis
H Holstege, W Pfeiffer, D Sie, M Hulsman, TJ Nicholas, CC Lee, T Ross, ...
Genome research 24 (5), 733-742, 2014
A meta-analysis of genome-wide association studies identifies multiple longevity genes
J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ...
Nature communications 10 (1), 3669, 2019
WISECONDOR: detection of fetal aberrations from shallow sequencing maternal plasma based on a within-sample comparison scheme
R Straver, EA Sistermans, H Holstege, A Visser, CBM Oudejans, ...
Nucleic acids research 42 (5), e31-e31, 2014
Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment
A Lacour, A Espinosa, E Louwersheimer, S Heilmann, I Hernández, ...
Molecular psychiatry 22 (1), 153-160, 2017
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ...
Nature communications 12 (1), 3417, 2021
Human and mouse oligonucleotide-based array CGH
P van den IJssel, M Tijssen, SF Chin, P Eijk, B Carvalho, E Hopmans, ...
Nucleic Acids Research 33 (22), e192-e192, 2005
A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization
YJ Chung, J Jonkers, H Kitson, H Fiegler, S Humphray, C Scott, S Hunt, ...
Genome research 14 (1), 188-196, 2004
Characterization of pathogenic SORL1 genetic variants for association with Alzheimer’s disease: a clinical interpretation strategy
H Holstege, SJ Van Der Lee, M Hulsman, TH Wong, JGJ Van Rooij, ...
European Journal of Human Genetics 25 (8), 973-981, 2017
Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases
R Guerreiro, V Escott-Price, L Darwent, L Parkkinen, O Ansorge, ...
Neurobiology of aging 38, 214. e7-214. e10, 2016
A High-Throughput Pharmaceutical Screen Identifies Compounds with Specific Toxicity against BRCA2-Deficient TumorsA Screen for Compounds Toxic to BRCA2-Deficient Tumors
B Evers, E Schut, E van der Burg, TM Braumuller, DA Egan, H Holstege, ...
Clinical Cancer Research 16 (1), 99-108, 2010
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the …
SJ Van Der Lee, OJ Conway, I Jansen, MM Carrasquillo, L Kleineidam, ...
Acta neuropathologica 138, 237-250, 2019
Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease
A Lechel, H Holstege, Y Begus, A Schienke, K Kamino, U Lehmann, ...
Gastroenterology 132 (4), 1465-1475, 2007
BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations
H Holstege, HM Horlings, A Velds, A Langerřd, AL Břrresen-Dale, ...
BMC cancer 10, 1-15, 2010
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Articles 1–20