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Steven Brem
Steven Brem
Professor of Neurosurgery, University of Pennsylvania
Verified email at uphs.upenn.edu
Title
Cited by
Cited by
Year
Effect of tumor-treating fields plus maintenance temozolomide vs maintenance temozolomide alone on survival in patients with glioblastoma: a randomized clinical trial
R Stupp, S Taillibert, A Kanner, W Read, DM Steinberg, B Lhermitte, ...
Jama 318 (23), 2306-2316, 2017
20372017
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
H Brem, S Piantadosi, PC Burger, M Walker, R Selker, NA Vick, K Black, ...
The Lancet 345 (8956), 1008-1012, 1995
17021995
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ...
Science translational medicine 9 (399), eaaa0984, 2017
14702017
Tumor angiogenesis: a quantitative method for histologic grading
S Brem, R Cotran, J Folkman
Journal of the National Cancer Institute 48 (2), 347-356, 1972
6591972
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity
F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ...
Cell 180 (1), 188-204. e22, 2020
6302020
Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, Epidemiology, and End …
FG Davis, S Freels, J Grutsch, S Barlas, S Brem
Journal of neurosurgery 88 (1), 1-10, 1998
6241998
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
LM Liau, K Ashkan, DD Tran, JL Campian, JE Trusheim, CS Cobbs, ...
Journal of translational medicine 16, 1-9, 2018
5272018
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant …
EA Chiocca, KM Abbed, S Tatter, DN Louis, FH Hochberg, F Barker, ...
Molecular Therapy 10 (5), 958-966, 2004
5212004
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
MR Rosenfeld, X Ye, JG Supko, S Desideri, SA Grossman, S Brem, ...
Autophagy 10 (8), 1359-1368, 2014
5122014
Central nervous system cancers, version 3.2020, NCCN clinical practice guidelines in oncology
LB Nabors, J Portnow, M Ahluwalia, J Baehring, H Brem, S Brem, ...
Journal of the National Comprehensive Cancer Network 18 (11), 1537-1570, 2020
3232020
Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.
SS Brem, D Zagzag, AM Tsanaclis, S Gately, MP Elkouby, SE Brien
The American journal of pathology 137 (5), 1121, 1990
2951990
Prolonged tumor dormancy by prevention of neovascularization in the vitreous
S Brem, H Brem, J Folkman, D Finkelstein, A Patz
Cancer research 36 (8), 2807-2812, 1976
2901976
Angiogenesis as a marker of preneoplastic lesions of the human breast
SS Brem, HM Jensen, PM Gullino
Cancer 41 (1), 239-244, 1978
2761978
Angiogenesis and cancer control: from concept to therapeutic trial
S Brem
Cancer Control 6 (5), 1-18, 1999
2311999
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia
SS Brem, PM Gullino, D Medina
Science 195 (4281), 880-882, 1977
2271977
Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and …
GA Soff, J Sanderowitz, S Gately, E Verrusio, I Weiss, S Brem, HC Kwaan
The Journal of clinical investigation 96 (6), 2593-2600, 1995
2121995
Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α
Q Wang, Z He, M Huang, T Liu, Y Wang, H Xu, H Duan, P Ma, L Zhang, ...
Nature communications 9 (1), 559, 2018
1942018
Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase …
S Takano, S Gately, ME Neville, WF Herblin, JL Gross, H Engelhard, ...
Cancer research 54 (10), 2654-2660, 1994
1891994
Inhibition of angiogenesis by Aβ peptides
D Paris, K Townsend, A Quadros, J Humphrey, J Sun, S Brem, ...
Angiogenesis 7, 75-85, 2004
1752004
Inhibition of neovascularization by an extract derived from vitreous.
I Preis, R Langer, H Brem, J Folkman
American journal of ophthalmology 84 (3), 323-328, 1977
1721977
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