Patrick Farber
Patrick Farber
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Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles
TJ Nott, E Petsalaki, P Farber, D Jervis, E Fussner, A Plochowietz, ...
Molecular cell 57 (5), 936-947, 2015
Pi-Pi contacts are an overlooked protein feature relevant to phase separation
RMC Vernon, PA Chong, B Tsang, TH Kim, A Bah, P Farber, H Lin, ...
elife 7, e31486, 2018
Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
JP Brady, PJ Farber, A Sekhar, YH Lin, R Huang, A Bah, TJ Nott, ...
Proceedings of the National Academy of Sciences 114 (39), E8194-E8203, 2017
ClpB N-terminal domain plays a regulatory role in protein disaggregation
R Rosenzweig, P Farber, A Velyvis, E Rennella, MP Latham, LE Kay
Proceedings of the National Academy of Sciences 112 (50), E6872-E6881, 2015
The effect of intrachain electrostatic repulsion on conformational disorder and dynamics of the Sic1 protein
B Liu, D Chia, V Csizmok, P Farber, JD Forman-Kay, CC Gradinaru
The Journal of Physical Chemistry B 118 (15), 4088-4097, 2014
Relaxation dispersion NMR spectroscopy for the study of protein allostery
PJ Farber, A Mittermaier
Biophysical reviews 7, 191-200, 2015
Analyzing protein folding cooperativity by differential scanning calorimetry and NMR spectroscopy
P Farber, H Darmawan, T Sprules, A Mittermaier
Journal of the American Chemical Society 132 (17), 6214-6222, 2010
Allosteric coupling between the intracellular coupling helix 4 and regulatory sites of the first nucleotide-binding domain of CFTR
JE Dawson, PJ Farber, JD Forman-Kay
PLoS One 8 (9), e74347, 2013
Concerted dynamics link allosteric sites in the PBX homeodomain
PJ Farber, A Mittermaier
Journal of molecular biology 405 (3), 819-830, 2011
Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits …
PA Chong, PJ Farber, RM Vernon, RP Hudson, AK Mittermaier, ...
Journal of Biological Chemistry 290 (38), 22862-22878, 2015
Side chain burial and hydrophobic core packing in protein folding transition states
PJ Farber, A Mittermaier
Protein Science 17 (4), 644-651, 2008
Local folding and misfolding in the PBX homeodomain from a three-state analysis of CPMG relaxation dispersion NMR data
PJ Farber, J Slager, AK Mittermaier
The Journal of Physical Chemistry B 116 (34), 10317-10329, 2012
Mechanism of amyloidogenesis of a bacterial AAA+ chaperone
SWS Chan, J Yau, C Ing, K Liu, P Farber, A Won, V Bhandari, ...
Structure 24 (7), 1095-1109, 2016
Active site dynamics in NADH oxidase from Thermus thermophilus studied by NMR spin relaxation
T Miletti, PJ Farber, A Mittermaier
Journal of biomolecular NMR 51, 71-82, 2011
NMR and Calorimetry of Biological Systems
A Mittermaier, P Farber
Biomolecular NMR Spectroscopy, 435-456, 2011
Phase Separation of Disordered Protein in the Formation of Membrane-Less Organelles
TJ Nott, P Farber, E Petsalakis, D Jervis, AJ Baldwin, JD Forman-Kay
Biophysical Journal 106 (2), 35a, 2014
Electrostatics-Dependent Shape of the Intrinsically-Disordered Protein Sic1
GW Gomes, B Liu, P Farber, V Csizmok, J Forman-Kay, CC Gradinaru
Biophysical Journal 106 (2), 689a, 2014
Development of PSMA x CD3 T-cell engagers using an integrated, functional approach
V de Puyraimond, M Mai, A Amash, N Blamey, G Conaghan, JF Scortecci, ...
Cancer Research 84 (6_Supplement), 6359-6359, 2024
Functional and specific T-cell engagers against a peptide-MHC tumor target
D Tortora, P Bergqvist, A Goodman, R Blackler, N Blamey, S Carrara, ...
Cancer Research 84 (6_Supplement), 2373-2373, 2024
Target-dependent considerations for the design of bispecific T-cell engagers
B Varied
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