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Derek M Murphy
Derek M Murphy
Twist Bioscience
Verified email at twistbioscience.com
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Cited by
Year
Direct detection of early-stage cancers using circulating tumor DNA
J Phallen, M Sausen, V Adleff, A Leal, C Hruban, J White, V Anagnostou, ...
Science translational medicine 9 (403), eaan2415, 2017
10252017
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients
M Sausen, J Phallen, V Adleff, S Jones, RJ Leary, MT Barrett, ...
Nature communications 6 (1), 7686, 2015
4712015
Personalized genomic analyses for cancer mutation discovery and interpretation
S Jones, V Anagnostou, K Lytle, S Parpart-Li, M Nesselbush, DR Riley, ...
Science translational medicine 7 (283), 283ra53-283ra53, 2015
4702015
MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2
NH Foley, IM Bray, A Tivnan, K Bryan, DM Murphy, PG Buckley, J Ryan, ...
Molecular cancer 9, 1-11, 2010
1922010
MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway
J Lynch, J Fay, M Meehan, K Bryan, KM Watters, DM Murphy, RL Stallings
Carcinogenesis 33 (5), 976-985, 2012
1742012
Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival
I Bray, K Bryan, S Prenter, PG Buckley, NH Foley, DM Murphy, L Alcock, ...
PloS one 4 (11), e7850, 2009
1432009
MicroRNA mediates DNA demethylation events triggered by retinoic acid during neuroblastoma cell differentiation
S Das, N Foley, K Bryan, KM Watters, I Bray, DM Murphy, PG Buckley, ...
Cancer research 70 (20), 7874-7881, 2010
1312010
Noninvasive detection of microsatellite instability and high tumor mutation burden in cancer patients treated with PD-1 blockade
A Georgiadis, JN Durham, LA Keefer, BR Bartlett, M Zielonka, D Murphy, ...
Clinical Cancer Research 25 (23), 7024-7034, 2019
1212019
Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation
DM Murphy, PG Buckley, K Bryan, S Das, L Alcock, NH Foley, S Prenter, ...
PloS one 4 (12), e8154, 2009
922009
NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes
DM Murphy, R Bejar, K Stevenson, D Neuberg, Y Shi, C Cubrich, ...
Leukemia 27 (10), 2077-2081, 2013
662013
Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis
DM Murphy, PG Buckley, K Bryan, KM Watters, J Koster, P van Sluis, ...
Molecular carcinogenesis 50 (6), 403-411, 2011
332011
Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma
DM Murphy, PG Buckley, S Das, KM Watters, K Bryan, RL Stallings
PLoS One 6 (6), e21436, 2011
292011
MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness
L Planells-Ferrer, J Urresti, A Soriano, S Reix, DM Murphy, JC Ferreres, ...
Cell death & disease 5 (9), e1401-e1401, 2014
232014
A non-invasive liquid biopsy approach for therapeutic stratification of lung cancer patients.
H Husain, J Phallen, S Parpart-Li, DM Murphy, V Adleff, SV Angiuoli, ...
Journal of Clinical Oncology 33 (15_suppl), e19082-e19082, 2015
42015
Circulating tumor DNA (ctDNA) as a prognostic marker for recurrence in resected pancreas cancer.
JSZ Wang, M Sausen, S Parpart-Li, DM Murphy, VE Velculescu, LD Wood, ...
Journal of Clinical Oncology 33 (15_suppl), 11025-11025, 2015
32015
A comprehensive noninvasive approach for the stratification of lung cancer patients for targeted therapies.
DM Murphy, SV Angiuoli, B Chesnick, K Galens, S Jones, M Kadan, ...
Journal of Clinical Oncology 33 (15_suppl), e22086-e22086, 2015
22015
Personalized Genomic Analyses for Cancer Mutation Discovery and Interpretation.
V Anagnostou, S Jones, K Lytle, S Parpart-Li, M Nesselbush, V Adleff, ...
Journal of Clinical Oncology 33 (15_suppl), 1529-1529, 2015
12015
A method for comprehensive genomic analysis of cell-free DNA.
S Parpart-Li, SV Angiuoli, B Chesnick, K Galens, S Jones, M Kadan, ...
Journal of Clinical Oncology 33 (15_suppl), e22070-e22070, 2015
12015
Clinical validation of a cell-free DNA liquid biopsy approach for noninvasive molecular profiling
M Nesselbush, S Angiuoli, LA Diaz, A Georgiadis, S Glynn, S Jones, ...
Cancer Research 77 (13_Supplement), 4954-4954, 2017
2017
Noninvasive detection of MET gene amplification in the circulation of cancer patients
M Sausen, SV Angiuoli, B Chesnick, K Galens, S Jones, M Kadan, L Kann, ...
Cancer Research 75 (15_Supplement), 5246-5246, 2015
2015
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