David Leib
David Leib
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy 12 (1), 1-222, 2016
HSV-1 ICP34. 5 confers neurovirulence by targeting the Beclin 1 autophagy protein
A Orvedahl, D Alexander, Z Tallóczy, Q Sun, Y Wei, W Zhang, D Burns, ...
Cell host & microbe 1 (1), 23-35, 2007
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9
A Krug, GD Luker, W Barchet, DA Leib, S Akira, M Colonna
Blood 103 (4), 1433-1437, 2004
Regulation of starvation-and virus-induced autophagy by the eIF2α kinase signaling pathway
Z Tallóczy, W Jiang, HW Virgin IV, DA Leib, D Scheuner, RJ Kaufman, ...
Proceedings of the National Academy of Sciences 99 (1), 190-195, 2002
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses
DJ Lenschow, C Lai, N Frias-Staheli, NV Giannakopoulos, A Lutz, T Wolff, ...
Proceedings of the National Academy of Sciences 104 (4), 1371-1376, 2007
Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
L English, M Chemali, J Duron, C Rondeau, A Laplante, D Gingras, ...
Nature immunology 10 (5), 480-487, 2009
Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
DM Coen, M Kosz-Vnenchak, JG Jacobson, DA Leib, CL Bogard, ...
Proceedings of the National Academy of Sciences 86 (12), 4736-4740, 1989
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency
DA Leib, DM Coen, CL Bogard, KA Hicks, DR Yager, DM Knipe, KL Tyler, ...
Journal of virology 63 (2), 759-768, 1989
A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency
DA Leib, CL Bogard, M Kosz-Vnenchak, KA Hicks, DM Coen, DM Knipe, ...
Journal of virology 63 (7), 2893-2900, 1989
Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo
DA Leib, TE Harrison, KM Laslo, MA Machalek, NJ Moorman, HW Virgin
The Journal of experimental medicine 189 (4), 663-672, 1999
Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene
DA Leib, MA Machalek, BRG Williams, RH Silverman, HW Virgin
Proceedings of the National Academy of Sciences 97 (11), 6097-6101, 2000
A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells
JG Jacobson, DA Leib, DJ Goldstein, CL Bogard, PA Schaffer, SK Weller, ...
Virology 173 (1), 276-283, 1989
Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice
GD Luker, JP Bardill, JL Prior, CM Pica, D Piwnica-Worms, DA Leib
Journal of virology 76 (23), 12149-12161, 2002
Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis
LI Strelow, DA Leib
Journal of virology 69 (11), 6779-6786, 1995
Interaction of ICP34.5 with Beclin 1 Modulates Herpes Simplex Virus Type 1 Pathogenesis through Control of CD4+ T-Cell Responses
DA Leib, DE Alexander, D Cox, J Yin, TA Ferguson
Journal of virology 83 (23), 12164-12171, 2009
The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and …
DA Leib, KC Nadeau, SA Rundle, PA Schaffer
Proceedings of the National Academy of Sciences 88 (1), 48-52, 1991
Analysis of the role of autophagy in replication of herpes simplex virus in cell culture
DE Alexander, SL Ward, N Mizushima, B Levine, DA Leib
Journal of virology 81 (22), 12128-12134, 2007
A neuron-specific role for autophagy in antiviral defense against herpes simplex virus
B Yordy, N Iijima, A Huttner, D Leib, A Iwasaki
Cell host & microbe 12 (3), 334-345, 2012
Construction and characterization of bacterial artificial chromosomes containing HSV-1 strains 17 and KOS
WW Gierasch, DL Zimmerman, SL Ward, TK VanHeyningen, JD Romine, ...
Journal of virological methods 135 (2), 197-206, 2006
A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency
D Pan, O Flores, JL Umbach, JM Pesola, P Bentley, PC Rosato, DA Leib, ...
Cell host & microbe 15 (4), 446-456, 2014
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