| Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction MP Wymann, G Bulgarelli-Leva, MJ Zvelebil, L Pirola, B Vanhaesebroeck, ... Molecular and cellular biology, 1996 | 912 | 1996 |
| The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective … AJ Folkes, K Ahmadi, WK Alderton, S Alix, SJ Baker, G Box, ... Journal of medicinal chemistry 51 (18), 5522-5532, 2008 | 871 | 2008 |
| Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. K Salim, MJ Bottomley, E Querfurth, MJ Zvelebil, I Gout, R Scaife, ... The EMBO journal 15 (22), 6241-6250, 1996 | 737 | 1996 |
| p110δ, a novel phosphoinositide 3-kinase in leukocytes B Vanhaesebroeck, MJ Welham, K Kotani, R Stein, PH Warne, ... Proceedings of the National Academy of Sciences 94 (9), 4330-4335, 1997 | 615 | 1997 |
| Phosphoinositide 3-kinase signalling–which way to target? MP Wymann, M Zvelebil, M Laffargue Trends in pharmacological sciences 24 (7), 366-376, 2003 | 598 | 2003 |
| Prediction of protein secondary structure and active sites using the alignment of homologous sequences MJ Zvelebil, GJ Barton, WR Taylor, MJE Sternberg Journal of molecular biology 195 (4), 957-961, 1987 | 598 | 1987 |
| Exploring the specificity of the PI3K family inhibitor LY294002 SI Gharbi, MJ Zvelebil, SJ Shuttleworth, T Hancox, N Saghir, JF Timms, ... Biochemical Journal 404 (1), 15-21, 2007 | 534 | 2007 |
| A human phosphatidylinositol 3‐kinase complex related to the yeast Vps34p‐Vps15p protein sorting system. S Volinia, R Dhand, B Vanhaesebroeck, LK MacDougall, R Stein, ... The EMBO journal 14 (14), 3339-3348, 1995 | 482 | 1995 |
| Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit N Miled, Y Yan, WC Hon, O Perisic, M Zvelebil, Y Inbar, ... science 317 (5835), 239-242, 2007 | 474 | 2007 |
| Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma MR Tanas, A Sboner, AM Oliveira, MR Erickson-Johnson, J Hespelt, ... Science translational medicine 3 (98), 98ra82-98ra82, 2011 | 384 | 2011 |
| Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system S Gharbi, P Gaffney, A Yang, MJ Zvelebil, R Cramer, MD Waterfield, ... Molecular & Cellular Proteomics 1 (2), 91-98, 2002 | 378 | 2002 |
| iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72–polymorphic p53 D Bergamaschi, Y Samuels, A Sullivan, M Zvelebil, H Breyssens, A Bisso, ... Nature genetics 38 (10), 1133-1141, 2006 | 349 | 2006 |
| Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin J Domin, F Pages, S Volinia, SE Rittenhouse, MJ Zvelebil, RC Stein, ... Biochemical Journal 326 (1), 139-147, 1997 | 347 | 1997 |
| IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis M Gyrd-Hansen, M Darding, M Miasari, MM Santoro, L Zender, W Xue, ... Nature cell biology 10 (11), 1309-1317, 2008 | 328 | 2008 |
| A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC. C Eng, DP Smith, LM Mulligan, CS Healey, MJ Zvelebil, TJ Stonehouse, ... Oncogene 10 (3), 509-513, 1995 | 322 | 1995 |
| Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases CH Reynolds, CJ Garwood, S Wray, C Price, S Kellie, T Perera, ... Journal of Biological Chemistry 283 (26), 18177-18186, 2008 | 294 | 2008 |
| Understanding bioinformatics M Zvelebil, JO Baum Garland Science, 2007 | 275 | 2007 |
| Proteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties MJ Page, B Amess, RR Townsend, R Parekh, A Herath, L Brusten, ... Proceedings of the National Academy of Sciences 96 (22), 12589-12594, 1999 | 272 | 1999 |
| Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid‐binding C2 domain R Uellner, MJ Zvelebil, J Hopkins, J Jones, LK MacDougall, BP Morgan, ... The EMBO journal, 1997 | 250 | 1997 |
| Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors A Arcaro, MJ Zvelebil, C Wallasch, A Ullrich, MD Waterfield, J Domin Molecular and cellular biology 20 (11), 3817-3830, 2000 | 236 | 2000 |
Stefano VoliniaUniversity of FerraraVerified email at unife.it
