| Argonaute proteins: key players in RNA silencing G Hutvagner, MJ Simard Nature reviews Molecular cell biology 9 (1), 22-32, 2008 | 1838 | 2008 |
| Sequence-specific inhibition of small RNA function G Hutvágner, MJ Simard, CC Mello, PD Zamore PLoS biology 2 (4), e98, 2004 | 863 | 2004 |
| Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi E Yigit, PJ Batista, Y Bei, KM Pang, CCG Chen, NH Tolia, L Joshua-Tor, ... Cell 127 (4), 747-757, 2006 | 805 | 2006 |
| Human let-7a miRNA blocks protein production on actively translating polyribosomes S Nottrott, MJ Simard, JD Richter Nature structural & molecular biology 13 (12), 1108-1114, 2006 | 657 | 2006 |
| Role for miR-204 in human pulmonary arterial hypertension A Courboulin, R Paulin, NJ Giguère, N Saksouk, T Perreault, J Meloche, ... Journal of Experimental Medicine 208 (3), 535-548, 2011 | 630 | 2011 |
| Methods and compositions for enhancing the efficacy and specificity of RNA silencing PD Zamore, G Hutvágner, D Schwarz, M Simard US Patent 7,750,144, 2010 | 448* | 2010 |
| Function, targets, and evolution of Caenorhabditis elegans piRNAs MP Bagijn, LD Goldstein, A Sapetschnig, EM Weick, S Bouasker, ... Science 337 (6094), 574-578, 2012 | 419 | 2012 |
| Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation L Zhong, MJ Simard, J Huot The FASEB Journal 32 (8), 4070-4084, 2018 | 223 | 2018 |
| A member of the polymerase β nucleotidyltransferase superfamily is required for RNA interference in C. elegans CCG Chen, MJ Simard, H Tabara, DR Brownell, JA McCollough, ... Current Biology 15 (4), 378-383, 2005 | 137 | 2005 |
| MicroRNA‐19a enhances proliferation of bronchial epithelial cells by targeting TGFβR2 gene in severe asthma I Haj‐Salem, R Fakhfakh, JC Bérubé, E Jacques, S Plante, MJ Simard, ... Allergy 70 (2), 212-219, 2015 | 127 | 2015 |
| The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans G Jannot, S Bajan, NJ Giguère, S Bouasker, IH Banville, S Piquet, ... EMBO reports 12 (6), 581-586, 2011 | 109 | 2011 |
| SRp30c is a repressor of 3′ splice site utilization MJ Simard, B Chabot Molecular and cellular biology 22 (12), 4001-4010, 2002 | 101 | 2002 |
| Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA‐guided gene silencing in vivo M Quévillon Huberdeau, DM Zeitler, J Hauptmann, A Bruckmann, ... The EMBO journal 36 (14), 2088-2106, 2017 | 99 | 2017 |
| Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2 A Vasquez-Rifo, G Jannot, J Armisen, M Labouesse, SIA Bukhari, ... PLoS One 7 (3), e33750, 2012 | 97 | 2012 |
| Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression AL Pin, F Houle, P Fournier, M Guillonneau, ÉR Paquet, MJ Simard, ... Journal of Biological Chemistry 287 (36), 30541-30551, 2012 | 96 | 2012 |
| The microRNA pathway controls germ cell proliferation and differentiation in C. elegans SIA Bukhari, A Vasquez-Rifo, D Gagné, ER Paquet, M Zetka, C Robert, ... Cell research 22 (6), 1034-1045, 2012 | 81 | 2012 |
| The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans GD Bossé, S Rüegger, MC Ow, A Vasquez-Rifo, EL Rondeau, VR Ambros, ... Molecular cell 50 (2), 281-287, 2013 | 77 | 2013 |
| miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF AL Pin, F Houle, M Guillonneau, ER Paquet, MJ Simard, J Huot Angiogenesis 15, 593-608, 2012 | 73 | 2012 |
| Somatic and germline microRNAs form distinct silencing complexes to regulate their target mRNAs differently A Dallaire, PM Frédérick, MJ Simard Developmental cell 47 (2), 239-247. e4, 2018 | 72 | 2018 |
| A guide to micro RNA‐mediated gene silencing M Quévillon Huberdeau, MJ Simard The FEBS journal 286 (4), 642-652, 2019 | 71 | 2019 |
Phillip D. ZamoreGretchen Stone Cook Professor of Biomedical Sciences, University of Massachusetts Medical SchoolVerified email at umassmed.edu
