|The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance|
C Wang, B Gong, PR Bushel, J Thierry-Mieg, D Thierry-Mieg, J Xu, ...
Nature biotechnology 32 (9), 926-932, 2014
|In silico toxicology protocols|
GJ Myatt, E Ahlberg, Y Akahori, D Allen, A Amberg, LT Anger, A Aptula, ...
Regulatory Toxicology and Pharmacology 96, 1-17, 2018
|Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity|
M Behl, JH Hsieh, TJ Shafer, WR Mundy, JR Rice, WA Boyd, ...
Neurotoxicology and teratology 52, 181-193, 2015
|Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges|
IK V. Katritch, ..., J. Xia, J-H. Hsieh, L-R. Zhang, X. S. Wang, …, R. C ...
Structure 22 (8), 1120-1139, 2014
|A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives|
K Pelch, JA Wignall, AE Goldstone, PK Ross, RB Blain, AJ Shapiro, ...
Toxicology 424, 152235, 2019
|Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway|
R Huang, S Sakamuru, MT Martin, DM Reif, RS Judson, KA Houck, ...
Scientific reports 4 (1), 5664, 2014
|An intuitive approach for predicting potential human health risk with the Tox21 10k library|
NS Sipes, JF Wambaugh, R Pearce, SS Auerbach, BA Wetmore, ...
Environmental science & technology 51 (18), 10786-10796, 2017
|Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity|
KR Ryan, O Sirenko, F Parham, JH Hsieh, EF Cromwell, RR Tice, M Behl
Neurotoxicology 53, 271-281, 2016
|Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human …|
A Alzualde, M Behl, NS Sipes, JH Hsieh, A Alday, RR Tice, RS Paules, ...
Neurotoxicology and teratology 70, 40-50, 2018
|Editor’s Highlight: Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditiselegans|
M Behl, JR Rice, MV Smith, CA Co, MF Bridge, JH Hsieh, JH Freedman, ...
Toxicological Sciences 154 (2), 241-252, 2016
|A data analysis pipeline accounting for artifacts in Tox21 quantitative high-throughput screening assays|
JH Hsieh, A Sedykh, R Huang, M Xia, RR Tice
Journal of biomolecular screening 20 (7), 887-897, 2015
|A high-throughput approach to identify specific neurotoxicants/developmental toxicants in human neuronal cell function assays|
J Delp, S Gutbier, S Klima, L Hoelting, K Pinto-Gil, JH Hsieh, M Aichem, ...
Altex 35 (2), 235, 2018
|Genetic toxicology in silico protocol|
C Hasselgren, E Ahlberg, Y Akahori, A Amberg, LT Anger, F Atienzar, ...
Regulatory Toxicology and Pharmacology 107, 104403, 2019
|Screening for developmental neurotoxicity at the national toxicology program: The future is here|
M Behl, K Ryan, JH Hsieh, F Parham, AJ Shapiro, BJ Collins, NS Sipes, ...
Toxicological Sciences 167 (1), 6-14, 2019
|Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach|
KC Hsu, CY Liu, TE Lin, JH Hsieh, TY Sung, HJ Tseng, JM Yang, ...
Scientific reports 7 (1), 3228, 2017
|Profiling animal toxicants by automatically mining public bioassay data: a big data approach for computational toxicology|
J Zhang, JH Hsieh, H Zhu
PLoS One 9 (6), e99863, 2014
|Cheminformatics meets molecular mechanics: a combined application of knowledge-based pose scoring and physical force field-based hit scoring functions improves the accuracy of …|
JH Hsieh, S Yin, XS Wang, S Liu, NV Dokholyan, A Tropsha
Journal of chemical information and modeling 52 (1), 16-28, 2012
|Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor|
CW Hsu, J Zhao, R Huang, JH Hsieh, J Hamm, X Chang, K Houck, M Xia
Scientific reports 4 (1), 6437, 2014
|Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library|
S Chen, JH Hsieh, R Huang, S Sakamuru, LY Hsin, M Xia, K Shockley, ...
Toxicological Sciences 147 (2), 446-457, 2015
|Differentiation of AmpC beta-lactamase binders vs. decoys using classification kNN QSAR modeling and application of the QSAR classifier to virtual screening|
JH Hsieh, XS Wang, D Teotico, A Golbraikh, A Tropsha
Journal of computer-aided molecular design 22, 593-609, 2008