BL Roth
BL Roth
Department of Pharmacology, University of North Carolina Medical School
Verified email at - Homepage
Cited by
Cited by
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
Consensus development conference on antipsychotic drugs and obesity and diabetes
American Diabetes Association,, American Psychiatric Association,, ...
Diabetes care 27 (2), 596-601, 2004
The expanded biology of serotonin
M Berger, JA Gray, BL Roth
Annual review of medicine 60, 355-366, 2009
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
BN Armbruster, X Li, MH Pausch, S Herlitze, BL Roth
Proceedings of the National Academy of Sciences 104 (12), 5163-5168, 2007
Relating protein pharmacology by ligand chemistry
MJ Keiser, BL Roth, BN Armbruster, P Ernsberger, JJ Irwin, BK Shoichet
Nature biotechnology 25 (2), 197-206, 2007
Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression
G Rajkowska, JJ Miguel-Hidalgo, J Wei, G Dilley, SD Pittman, HY Meltzer, ...
Biological psychiatry 45 (9), 1085-1098, 1999
Predicting new molecular targets for known drugs
MJ Keiser, V Setola, JJ Irwin, C Laggner, AI Abbas, SJ Hufeisen, ...
Nature 462 (7270), 175-181, 2009
DREADDs for neuroscientistss
BL Roth
Neuron, 2016
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
MJ Krashes, S Koda, CP Ye, SC Rogan, AC Adams, DS Cusher, ...
The Journal of clinical investigation 121 (4), 1424-1428, 2011
Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia
BL Roth, DJ Sheffler, WK Kroeze
Nature reviews Drug discovery 3 (4), 353-359, 2004
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology
DA Shapiro, S Renock, E Arrington, LA Chiodo, LX Liu, DR Sibley, ...
Neuropsychopharmacology 28 (8), 1400-1411, 2003
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
WK Kroeze, SJ Hufeisen, BA Popadak, SM Renock, SA Steinberg, ...
Neuropsychopharmacology 28 (3), 519-526, 2003
Structure of the human κ-opioid receptor in complex with JDTic
H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ...
Nature 485 (7398), 327-332, 2012
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
MS Goldberg, SM Fleming, JJ Palacino, C Cepeda, HA Lam, A Bhatnagar, ...
Journal of Biological Chemistry 278 (44), 43628-43635, 2003
Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors
GM Alexander, SC Rogan, AI Abbas, BN Armbruster, Y Pei, JA Allen, ...
Neuron 63 (1), 27-39, 2009
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
BL Roth, SC Craigo, MS Choudhary, A Uluer, FJ Monsma Jr, Y Shen, ...
Journal of Pharmacology and Experimental Therapeutics 268 (3), 1403-1410, 1994
Salvinorin A: a potent naturally occurring nonnitrogenous κ opioid selective agonist
BL Roth, K Baner, R Westkaemper, D Siebert, KC Rice, SA Steinberg, ...
Proceedings of the National Academy of Sciences 99 (18), 11934-11939, 2002
Structure-based discovery of opioid analgesics with reduced side effects
A Manglik, H Lin, DK Aryal, JD McCorvy, D Dengler, G Corder, A Levit, ...
Nature 537 (7619), 185-190, 2016
Evidence for Possible Involvement of 5-HT2B Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications
RB Rothman, MH Baumann, JE Savage, L Rauser, A McBride, ...
Circulation 102 (23), 2836-2841, 2000
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