| T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection RJ Lee, G Xiong, JM Kofonow, B Chen, A Lysenko, P Jiang, V Abraham, ... The Journal of clinical investigation 122 (11), 4145-4159, 2012 | 581 | 2012 |
| Bitter and sweet taste receptors regulate human upper respiratory innate immunity RJ Lee, JM Kofonow, PL Rosen, AP Siebert, B Chen, L Doghramji, ... The Journal of clinical investigation 124 (3), 1393-1405, 2014 | 428 | 2014 |
| Chronic rhinosinusitis pathogenesis WW Stevens, RJ Lee, RP Schleimer, NA Cohen Journal of Allergy and Clinical Immunology 136 (6), 1442-1453, 2015 | 404 | 2015 |
| The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery ND Adappa, Z Zhang, JN Palmer, DW Kennedy, L Doghramji, A Lysenko, ... International forum of allergy & rhinology 4 (1), 3-7, 2014 | 175 | 2014 |
| CALHM3 is essential for rapid ion channel-mediated purinergic neurotransmission of GPCR-mediated tastes Z Ma, A Taruno, M Ohmoto, M Jyotaki, JC Lim, H Miyazaki, N Niisato, ... Neuron 98 (3), 547-561. e10, 2018 | 170 | 2018 |
| Taste receptors in innate immunity RJ Lee, NA Cohen Cellular and molecular life sciences 72, 217-236, 2015 | 169 | 2015 |
| Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability Z Ma, AP Siebert, KH Cheung, RJ Lee, B Johnson, AS Cohen, ... Proceedings of the National Academy of Sciences 109 (28), E1963-E1971, 2012 | 169 | 2012 |
| First contact: the role of respiratory cilia in host-pathogen interactions in the airways LE Kuek, RJ Lee American Journal of Physiology-Lung Cellular and Molecular Physiology 319 (4 …, 2020 | 153 | 2020 |
| Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein RJ Lee, C Liu, C Harty, AA McCracken, M Latterich, K Römisch, ... The EMBO journal 23 (11), 2206-2215, 2004 | 147 | 2004 |
| Bitter and sweet taste receptors in the respiratory epithelium in health and disease RJ Lee, NA Cohen Journal of molecular medicine 92, 1235-1244, 2014 | 121 | 2014 |
| Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells RJ Lee, BM Hariri, DB McMahon, B Chen, L Doghramji, ND Adappa, ... Science signaling 10 (495), eaam7703, 2017 | 118 | 2017 |
| Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components RJ Lee, B Chen, KM Redding, RF Margolskee, NA Cohen Innate immunity 20 (6), 606-617, 2014 | 114 | 2014 |
| Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor BM Hariri, DB McMahon, B Chen, JR Freund, CJ Mansfield, LJ Doghramji, ... Journal of Biological Chemistry 292 (20), 8484-8497, 2017 | 110 | 2017 |
| Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention ND Adappa, TJ Howland, JN Palmer, DW Kennedy, L Doghramji, ... International Forum of Allergy & Rhinology, 2013 | 103 | 2013 |
| Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling JR Freund, CJ Mansfield, LJ Doghramji, ND Adappa, JN Palmer, ... Journal of Biological Chemistry 293 (25), 9824-9840, 2018 | 101 | 2018 |
| TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis ND Adappa, D Farquhar, JN Palmer, DW Kennedy, L Doghramji, ... International forum of allergy & rhinology 6 (1), 25-33, 2016 | 99 | 2016 |
| The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis RJ Lee, NA Cohen American journal of rhinology & allergy 27 (4), 283-286, 2013 | 97 | 2013 |
| Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis RJ Lee, NA Cohen Current opinion in allergy and clinical immunology 15 (1), 14-20, 2015 | 95 | 2015 |
| cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways RJ Lee, JK Foskett The Journal of clinical investigation 120 (9), 3137-3148, 2010 | 93 | 2010 |
| Taste receptors in upper airway innate immunity RM Carey, RJ Lee Nutrients 11 (9), 2017, 2019 | 86 | 2019 |
James N. PalmerProfessor and Director, Division of Rhinology, University of PennsylvaniaVerified email at pennmedicine.upenn.edu
