Follow
Colin Hockings
Colin Hockings
Department of Chemical Engineering & Biotechnology, University of Cambridge
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis
PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ...
Cell 152 (3), 519-531, 2013
6322013
Bax dimerizes via a symmetric BH3: groove interface during apoptosis
G Dewson, S Ma, P Frederick, C Hockings, I Tan, T Kratina, RM Kluck
Cell Death & Differentiation 19 (4), 661-670, 2012
2062012
VDAC2 enables BAX to mediate apoptosis and limit tumor development
HS Chin, MX Li, IKL Tan, RL Ninnis, B Reljic, K Scicluna, LF Dagley, ...
Nature communications 9 (1), 4976, 2018
1262018
Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax
C Hockings, K Anwari, RL Ninnis, J Brouwer, M O'Hely, M Evangelista, ...
Cell death & disease 6 (4), e1735-e1735, 2015
952015
Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis
S Ma, C Hockings, K Anwari, T Kratina, S Fennell, M Lazarou, MT Ryan, ...
Journal of Biological Chemistry 288 (36), 26027-26038, 2013
842013
A highly porous metal-organic framework system to deliver payloads for gene knockdown
MH Teplensky, M Fantham, C Poudel, C Hockings, M Lu, A Guna, ...
Chem 5 (11), 2926-2941, 2019
772019
Mcl-1 and Bcl-xL sequestration of Bak confers differential resistance to BH3-only proteins
C Hockings, AE Alsop, SC Fennell, EF Lee, WD Fairlie, G Dewson, ...
Cell Death & Differentiation 25 (4), 721-734, 2018
542018
Physiological restraint of Bak by Bcl-xL is essential for cell survival
EF Lee, S Grabow, S Chappaz, G Dewson, C Hockings, RM Kluck, ...
Genes & development 30 (10), 1240-1250, 2016
542016
BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
MX Li, IKL Tan, SB Ma, C Hockings, T Kratina, MA Dengler, AE Alsop, ...
Proceedings of the National Academy of Sciences 114 (29), 7629-7634, 2017
382017
Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells
CL Novo, EV Wong, C Hockings, C Poudel, E Sheekey, M Wiese, ...
Nature communications 13 (1), 3525, 2022
322022
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies
J Lautenschläger, S Wagner-Valladolid, AD Stephens, ...
Journal of Biological Chemistry 295 (30), 10138-10152, 2020
292020
A waveguide imaging platform for live‐cell TIRF imaging of neurons over large fields of view
IS Opstad, F Ströhl, M Fantham, C Hockings, O Vanderpoorten, ...
Journal of Biophotonics 13 (6), e201960222, 2020
162020
Endoplasmic Reticulum morphological regulation by RTN4/NOGO modulates neuronal regeneration by curbing luminal transport
T Konno, P Parutto, DMD Bailey, V Davì, C Crapart, MA Awadelkareem, ...
bioRxiv, 2021.05. 10.441946, 2021
122021
Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
EM Linossi, K Li, G Veggiani, C Tan, F Dehkhoda, C Hockings, DJ Calleja, ...
Nature Communications 12 (1), 7032, 2021
82021
Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion
L Chen-Wichmann, M Shvartsman, C Preiss, C Hockings, R Windisch, ...
Oncogene 38 (2), 261-272, 2019
62019
Illuminating chromatin compaction in live cells and fixed tissues using SiR-DNA fluorescence lifetime
C Hockings, C Poudel, KA Feeney, CL Novo, MS Hamouda, I Mela, ...
BioRxiv, 2020.05. 02.073536, 2020
52020
Avoiding adsorption of Bcl-2 proteins to plasticware is important for accurate quantitation
C Hockings, S Iyer, RT Uren, RM Kluck
Cell Death & Differentiation 26 (5), 794-795, 2019
22019
BAX requires VDAC2 to mediate apoptosis and to limit tumor development
HS Chin, MF van Delft, RL Ninnis, MX Li, IKL Tan, B Reljic, K Scicluna, ...
BioRxiv, 266668, 2018
12018
Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands (vol 4, 7951, 2023)
EM Linossi, K Li, G Veggiani, C Tan, F Dehkhoda, C Hockings, DJ Calleja, ...
NATURE COMMUNICATIONS 14 (1), 2023
2023
Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
EM Linossi, K Li, G Veggiani, C Tan, F Dehkhoda, C Hockings, DJ Calleja, ...
nature communications 14, 2023
2023
The system can't perform the operation now. Try again later.
Articles 1–20