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Alexandra Gylfe
Alexandra Gylfe
Research and Development Lead, Human Longevity, Inc.
Verified email at humanlongevity.com
Title
Cited by
Cited by
Year
CTCF/cohesin-binding sites are frequently mutated in cancer
R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ...
Nature genetics 47 (7), 818-821, 2015
4502015
Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer
T Cajuso, UA Hänninen, J Kondelin, AE Gylfe, T Tanskanen, R Katainen, ...
International journal of cancer 135 (3), 611-623, 2014
1282014
Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis
S May-Wilson, A Sud, PJ Law, K Palin, S Tuupanen, A Gylfe, ...
European Journal of Cancer 84, 228-238, 2017
992017
Eleven candidate susceptibility genes for common familial colorectal cancer
AE Gylfe, R Katainen, J Kondelin, T Tanskanen, T Cajuso, U Hänninen, ...
PLoS genetics 9 (10), e1003876, 2013
952013
Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer
H Rodriguez‐Broadbent, PJ Law, A Sud, K Palin, S Tuupanen, A Gylfe, ...
International journal of cancer 140 (12), 2701-2708, 2017
832017
Identification of 33 candidate oncogenes by screening for base-specific mutations
S Tuupanen, UA Hänninen, J Kondelin, P Von Nandelstadh, T Cajuso, ...
British journal of cancer 111 (8), 1657-1662, 2014
782014
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability
AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ...
Gastroenterology 145 (3), 540-543. e22, 2013
762013
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer
D Jarvis, JS Mitchell, PJ Law, K Palin, S Tuupanen, A Gylfe, UA Hänninen, ...
British journal of cancer 115 (2), 266-272, 2016
712016
A Finnish founder mutation in RAD51D: analysis in breast, ovarian, prostate, and colorectal cancer
LM Pelttari, J Kiiski, R Nurminen, A Kallioniemi, J Schleutker, A Gylfe, ...
Journal of medical genetics 49 (7), 429-432, 2012
612012
Somatic mutations and germline sequence variants in patients with familial colorectal cancer
AE Gylfe, J Sirkiä, M Ahlsten, H Järvinen, JP Mecklin, A Karhu, ...
International journal of cancer 127 (12), 2974-2980, 2010
592010
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease
G Orlando, PJ Law, K Palin, S Tuupanen, A Gylfe, UA Hänninen, T Cajuso, ...
Human molecular genetics 25 (11), 2349-2359, 2016
482016
Systematic search for rare variants in Finnish early-onset colorectal cancer patients
T Tanskanen, AE Gylfe, R Katainen, M Taipale, L Renkonen-Sinisalo, ...
Cancer genetics 208 (1-2), 35-40, 2015
322015
Genome‐wide association study and meta‐analysis in Northern European populations replicate multiple colorectal cancer risk loci
T Tanskanen, L Van Den Berg, N Välimäki, M Aavikko, E Ness‐Jensen, ...
International Journal of Cancer 142 (3), 540-546, 2018
312018
Characterization of the colorectal cancer–associated enhancer MYC-335 at 8q24: the role of rs67491583
S Tuupanen, J Yan, M Turunen, AE Gylfe, E Kaasinen, L Li, C Eng, ...
Cancer genetics 205 (1-2), 25-33, 2012
282012
Comprehensive evaluation of protein coding mononucleotide microsatellites in microsatellite-unstable colorectal cancer
J Kondelin, AE Gylfe, S Lundgren, T Tanskanen, J Hamberg, M Aavikko, ...
Cancer Research 77 (15), 4078-4088, 2017
262017
Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients
T Tanskanen, AE Gylfe, R Katainen, M Taipale, L Renkonen-Sinisalo, ...
Scandinavian journal of gastroenterology 48 (6), 672-678, 2013
212013
High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint
I Niittymäki, A Gylfe, L Laine, M Laakso, HJ Lehtonen, J Kondelin, ...
Carcinogenesis 32 (3), 305-311, 2011
162011
Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer
J Kondelin, K Salokas, L Saarinen, K Ovaska, H Rauanheimo, RM Plaketti, ...
EMBO molecular medicine 10 (9), e8552, 2018
142018
Screening of Finnish RAD51Cfounder mutations in prostate and colorectal cancer patients
LM Pelttari, R Nurminen, A Gylfe, LA Aaltonen, J Schleutker, ...
BMC cancer 12, 1-4, 2012
132012
3′-UTR poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer with nearly perfect sensitivity
J Kondelin, S Tuupanen, AE Gylfe, M Aavikko, L Renkonen-Sinisalo, ...
Familial cancer 14, 449-453, 2015
32015
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