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Benjamin Ng
Benjamin Ng
National Heart Centre Singapore
Verified email at nus.edu.sg
Title
Cited by
Cited by
Year
IL-11 is a crucial determinant of cardiovascular fibrosis
S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ...
Nature 552 (7683), 110-115, 2017
5262017
Titin-truncating variants affect heart function in disease cohorts and the general population
S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, ...
Nature genetics 49 (1), 46-53, 2017
2932017
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ...
Science translational medicine 11 (511), eaaw1237, 2019
2162019
Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis
AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ...
Gastroenterology 157 (3), 777-792. e14, 2019
2102019
Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression
TM Liu, WM Ng, HS Tan, D Vinitha, Z Yang, JB Fan, Y Zou, JH Hui, ...
Stem cells and development 22 (2), 268-278, 2013
902013
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ...
Nature communications 12 (1), 66, 2021
832021
Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway
B Ng, SA Cook, S Schafer
Experimental & Molecular Medicine 52 (12), 1871-1878, 2020
602020
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models
WW Lim, B Corden, B Ng, K Vanezis, G D’Agostino, AA Widjaja, WH Song, ...
Scientific reports 10 (1), 17853, 2020
502020
Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease
B Ng, J Dong, S Viswanathan, AA Widjaja, BS Paleja, E Adami, NSJ Ko, ...
The FASEB Journal 34 (9), 11802-11815, 2020
482020
Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
WW Lim, B Ng, A Widjaja, C Xie, L Su, N Ko, SY Lim, XY Kwek, S Lim, ...
PLoS One 15 (1), e0227505, 2020
472020
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ...
Science Translational Medicine 13 (597), eaba8146, 2021
452021
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
E Adami, S Viswanathan, AA Widjaja, B Ng, S Chothani, N Zhihao, J Tan, ...
Rheumatology 60 (12), 5820-5826, 2021
392021
Loss of protein kinase C-δ protects against LPS-induced osteolysis owing to an intrinsic defect in osteoclastic bone resorption
EC Khor, T Abel, J Tickner, SM Chim, C Wang, T Cheng, B Ng, PY Ng, ...
PloS one 8 (8), e70815, 2013
302013
Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis
B Ng, AA Widjaja, S Viswanathan, J Dong, SP Chothani, S Lim, ...
Scientific Reports 11 (1), 14088, 2021
282021
Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo
J Zhou, B Ng, NSJ Ko, LR Fiedler, E Khin, A Lim, NE Sahib, Y Wu, ...
Human molecular genetics 28 (12), 1971-1981, 2019
272019
Inhibition of IL11 signaling reduces aortic pathology in murine marfan syndrome
WW Lim, J Dong, B Ng, AA Widjaja, C Xie, L Su, XY Kwek, NGZ Tee, ...
Circulation Research 130 (5), 728-740, 2022
262022
IL11 activates pancreatic stellate cells and causes pancreatic inflammation, fibrosis and atrophy in a mouse model of pancreatitis
B Ng, S Viswanathan, AA Widjaja, WW Lim, SG Shekeran, JWT Goh, ...
International Journal of Molecular Sciences 23 (7), 3549, 2022
192022
Treatment of SMC mediated disease
SA Cook, S Schaefer, WW Lim, BWM Ng
US Patent 11,780,898, 2023
142023
Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments
X Yang, D Teguh, JP Wu, B He, TB Kirk, S Qin, S Li, H Chen, W Xue, B Ng, ...
Arthritis Research & Therapy 17, 1-8, 2015
132015
Redefining Interleukin 11 as a regeneration-limiting hepatotoxin
AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, BK Singh, WW Lim, ...
bioRxiv, 830018, 2019
122019
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