| PrecisionFDA Truth Challenge V2: Calling variants from short and long reads in difficult-to-map regions ND Olson, J Wagner, J McDaniel, SH Stephens, ST Westreich, ... Cell genomics 2 (5), 2022 | 134 | 2022 |
| An ensemble approach to accurately detect somatic mutations using SomaticSeq LT Fang, PT Afshar, A Chhibber, M Mohiyuddin, Y Fan, JC Mu, G Gibeling, ... Genome biology 16, 1-13, 2015 | 126 | 2015 |
| Effects of salt concentrations and bending energy on the extent of ejection of phage genomes A Evilevitch, LT Fang, AM Yoffe, M Castelnovo, DC Rau, VA Parsegian, ... Biophysical journal 94 (3), 1110-1120, 2008 | 104 | 2008 |
| Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing W Xiao, L Ren, Z Chen, LT Fang, Y Zhao, J Lack, M Guan, B Zhu, ... Nature biotechnology 39 (9), 1141-1150, 2021 | 102 | 2021 |
| Salt-Dependent DNA-DNA Spacings in Intact Bacteriophage Reflect Relative Importance <?format ?>of DNA Self-Repulsion and Bending Energies X Qiu, DC Rau, VA Parsegian, LT Fang, CM Knobler, WM Gelbart Physical review letters 106 (2), 028102, 2011 | 78 | 2011 |
| Gremlin is Overexpressed in Lung Adenocarcinoma and Increases Cell Growth and Proliferation in Normal Lung Cells MS Mulvihill, YW Kwon, S Lee, LT Fang, H Choi, R Ray, HC Kang, ... PloS one 7 (8), e42264, 2012 | 65 | 2012 |
| Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing LT Fang, B Zhu, Y Zhao, W Chen, Z Yang, L Kerrigan, K Langenbach, ... Nature biotechnology 39 (9), 1151-1160, 2021 | 60* | 2021 |
| Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas HC Kang, HK Kim, S Lee, P Mendez, JW Kim, G Woodard, JH Yoon, ... Oncotarget 7 (7), 8321, 2016 | 59 | 2016 |
| Targeting Gli transcription activation by small molecule suppresses tumor growth G Bosco-Clément, F Zhang, Z Chen, HM Zhou, H Li, I Mikami, T Hirata, ... Oncogene 33 (16), 2087-2097, 2014 | 52 | 2014 |
| Concordance of genomic alterations by next-generation sequencing in tumor tissue versus cell-free DNA in stage I–IV non–small cell lung cancer J Jiang, HP Adams, L Yao, S Yaung, P Lal, A Balasubramanyam, ... The Journal of Molecular Diagnostics 22 (2), 228-235, 2020 | 43 | 2020 |
| The size of RNA as an ideal branched polymer LT Fang, WM Gelbart, A Ben-Shaul The Journal of chemical physics 135 (15), 2011 | 39 | 2011 |
| Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis LT Fang, S Lee, H Choi, HK Kim, G Jew, HC Kang, L Chen, D Jablons, ... International Journal of Oncology 44 (1), 211-221, 2013 | 36 | 2013 |
| Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study Y Zhao, LT Fang, T Shen, S Choudhari, K Talsania, X Chen, J Shetty, ... Scientific data 8 (1), 296, 2021 | 31 | 2021 |
| Lung tumourigenesis in a conditional Cul4A transgenic mouse model YL Yang, MS Hung, Y Wang, J Ni, JH Mao, D Hsieh, A Au, A Kumar, ... The Journal of pathology 233 (2), 113-123, 2014 | 26 | 2014 |
| LongISLND: in silico sequencing of lengthy and noisy datatypes B Lau, M Mohiyuddin, JC Mu, LT Fang, N Bani Asadi, C Dallett, HYK Lam Bioinformatics 32 (24), 3829-3832, 2016 | 25 | 2016 |
| CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells S Zhang, YL Yang, Y Wang, B You, Y Dai, G Chan, D Hsieh, IJ Kim, ... Journal of Experimental & Clinical Cancer Research 33, 1-12, 2014 | 21 | 2014 |
| Structural variant analysis of a cancer reference cell line sample using multiple sequencing technologies K Talsania, T Shen, X Chen, E Jaeger, Z Li, Z Chen, W Chen, B Tran, ... Genome Biology 23 (1), 255, 2022 | 20 | 2022 |
| The force acting on a polymer partially confined in a tube P Prinsen, LT Fang, AM Yoffe, CM Knobler, WM Gelbart The Journal of Physical Chemistry B 113 (12), 3873-3879, 2009 | 18 | 2009 |
| The end-to-end distance of RNA as a randomly self-paired polymer LT Fang Journal of theoretical biology 280 (1), 101-107, 2011 | 16 | 2011 |
| Achieving robust somatic mutation detection with deep learning models derived from reference data sets of a cancer sample SME Sahraeian, LT Fang, K Karagiannis, M Moos, S Smith, ... Genome Biology 23 (1), 12, 2022 | 15 | 2022 |
Aron YoffeUCLA Dept. of Chemistry and BiochemistryVerified email at chem.ucla.edu
