Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus L Guillot, R Le Goffic, S Bloch, N Escriou, S Akira, M Chignard, M Si-Tahar Journal of Biological Chemistry 280 (7), 5571-5580, 2005 | 897 | 2005 |
Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular … L Guillot, S Medjane, K Le-Barillec, V Balloy, C Danel, M Chignard, ... Journal of Biological Chemistry 279 (4), 2712-2718, 2004 | 469 | 2004 |
Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4 L Guillot, V Balloy, FX McCormack, DT Golenbock, M Chignard, ... The Journal of Immunology 168 (12), 5989-5992, 2002 | 410 | 2002 |
Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis H Corvol, SM Blackman, PY Boëlle, PJ Gallins, RG Pace, JR Stonebraker, ... Nature communications 6 (1), 8382, 2015 | 295 | 2015 |
Alveolar epithelial cells: master regulators of lung homeostasis L Guillot, N Nathan, O Tabary, G Thouvenin, P Le Rouzic, H Corvol, ... The international journal of biochemistry & cell biology 45 (11), 2568-2573, 2013 | 289 | 2013 |
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity M Divangahi, S Mostowy, F Coulombe, R Kozak, L Guillot, F Veyrier, ... The Journal of immunology 181 (10), 7157-7165, 2008 | 276 | 2008 |
Cystic fibrosis liver disease: outcomes and risk factors in a large cohort of French patients PY Boëlle, D Debray, L Guillot, A Clement, H Corvol, ... Hepatology 69 (4), 1648-1656, 2019 | 131 | 2019 |
Innate immune signaling and proteolytic pathways in the resolution or exacerbation of SARS-CoV-2 in Covid-19: key therapeutic targets? JM Sallenave, L Guillot Frontiers in immunology 11, 550828, 2020 | 130 | 2020 |
Benign hereditary chorea: phenotype, prognosis, therapeutic outcome and long term follow-up in a large series with new mutations in the TITF1/NKX2-1 gene D Gras, L Jonard, E Roze, S Chantot-Bastaraud, J Koht, J Motte, ... Journal of Neurology, Neurosurgery & Psychiatry 83 (10), 956-962, 2012 | 128 | 2012 |
NKX2‐1 mutations leading to surfactant protein promoter dysregulation cause interstitial lung disease in “Brain‐Lung‐Thyroid Syndrome” L Guillot, A Carré, G Szinnai, M Castanet, E Tron, F Jaubert, I Broutin, ... Human mutation 31 (2), E1146-E1162, 2010 | 128 | 2010 |
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo M Le Gars, D Descamps, D Roussel, E Saussereau, L Guillot, M Ruffin, ... American journal of respiratory and critical care medicine 187 (2), 170-179, 2013 | 118 | 2013 |
Characteristics of disorders associated with genetic mutations of surfactant protein C G Thouvenin, R Abou Taam, F Flamein, L Guillot, M Le Bourgeois, P Reix, ... Archives of disease in childhood 95 (6), 449-454, 2010 | 116 | 2010 |
New surfactant protein C gene mutations associated with diffuse lung disease L Guillot, R Epaud, G Thouvenin, L Jonard, A Mohsni, R Couderc, ... Journal of medical genetics 46 (7), 490-494, 2009 | 114 | 2009 |
Molecular and cellular characteristics of ABCA3 mutations associated with diffuse parenchymal lung diseases in children F Flamein, L Riffault, C Muselet-Charlier, J Pernelle, D Feldmann, ... Human molecular genetics 21 (4), 765-775, 2012 | 105 | 2012 |
Regulation of angiopoietin expression by bacterial lipopolysaccharide M Mofarrahi, T Nouh, S Qureshi, L Guillot, D Mayaki, SNA Hussain American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (5 …, 2008 | 91 | 2008 |
Lung disease modifier genes in cystic fibrosis L Guillot, J Beucher, O Tabary, P Le Rouzic, A Clement, H Corvol The international journal of biochemistry & cell biology 52, 83-93, 2014 | 88 | 2014 |
Lung alveolar epithelium and interstitial lung disease H Corvol, F Flamein, R Epaud, A Clement, L Guillot The international journal of biochemistry & cell biology 41 (8-9), 1643-1651, 2009 | 84 | 2009 |
Enhanced Innate Immune Responsiveness to Pulmonary Cryptococcus neoformans Infection Is Associated with Resistance to Progressive Infection L Guillot, SF Carroll, R Homer, ST Qureshi Infection and immunity 76 (10), 4745-4756, 2008 | 80 | 2008 |
Translating the genetics of cystic fibrosis to personalized medicine H Corvol, KE Thompson, O Tabary, P Le Rouzic, L Guillot Translational research 168, 40-49, 2016 | 73 | 2016 |
Anoctamin 1 dysregulation alters bronchial epithelial repair in cystic fibrosis M Ruffin, M Voland, S Marie, M Bonora, E Blanchard, S Blouquit-Laye, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 57 | 2013 |