| Impact of cytosine methylation on DNA binding specificities of human transcription factors Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ... Science 356 (6337), eaaj2239, 2017 | 1091 | 2017 |
| MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011 | 728 | 2011 |
| DNA-dependent formation of transcription factor pairs alters their binding specificity A Jolma, Y Yin, KR Nitta, K Dave, A Popov, M Taipale, M Enge, T Kivioja, ... Nature 527 (7578), 384-388, 2015 | 545 | 2015 |
| Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ... Cell 154 (4), 801-813, 2013 | 382 | 2013 |
| Identification of pathways regulating cell size and cell-cycle progression by RNAi M Björklund, M Taipale, M Varjosalo, J Saharinen, J Lahdenperä, ... Nature 439 (7079), 1009-1013, 2006 | 316 | 2006 |
| The interaction landscape between transcription factors and the nucleosome F Zhu, L Farnung, E Kaasinen, B Sahu, Y Yin, B Wei, SO Dodonova, ... Nature 562 (7725), 76-81, 2018 | 296 | 2018 |
| The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera V Ahola, R Lehtonen, P Somervuo, L Salmela, P Koskinen, P Rastas, ... Nature communications 5 (1), 4737, 2014 | 236 | 2014 |
| Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ... Science 338 (6112), 1360-1363, 2012 | 236 | 2012 |
| Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer T Cajuso, UA Hänninen, J Kondelin, AE Gylfe, T Tanskanen, R Katainen, ... International journal of cancer 135 (3), 611-623, 2014 | 128 | 2014 |
| Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12 N Mäkinen, M Aavikko, T Heikkinen, M Taipale, J Taipale, ... PLoS genetics 12 (2), e1005850, 2016 | 111 | 2016 |
| Eleven candidate susceptibility genes for common familial colorectal cancer AE Gylfe, R Katainen, J Kondelin, T Tanskanen, T Cajuso, U Hänninen, ... PLoS genetics 9 (10), e1003876, 2013 | 95 | 2013 |
| Identification of 33 candidate oncogenes by screening for base-specific mutations S Tuupanen, UA Hänninen, J Kondelin, P Von Nandelstadh, T Cajuso, ... British journal of cancer 111 (8), 1657-1662, 2014 | 78 | 2014 |
| Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans E Kaasinen, O Kuismin, K Rajamäki, H Ristolainen, M Aavikko, J Kondelin, ... Nature communications 10 (1), 1252, 2019 | 76 | 2019 |
| Identification of candidate oncogenes in human colorectal cancers with microsatellite instability AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ... Gastroenterology 145 (3), 540-543. e22, 2013 | 76 | 2013 |
| Exome-wide somatic mutation characterization of small bowel adenocarcinoma UA Hänninen, R Katainen, T Tanskanen, RM Plaketti, R Laine, ... PLoS genetics 14 (3), e1007200, 2018 | 75 | 2018 |
| Flight‐induced changes in gene expression in the Glanville fritillary butterfly J Kvist, ALK Mattila, P Somervuo, V Ahola, P Koskinen, L Paulin, ... Molecular Ecology 24 (19), 4886-4900, 2015 | 38 | 2015 |
| A protein activity assay to measure global transcription factor activity reveals determinants of chromatin accessibility B Wei, A Jolma, B Sahu, LM Orre, F Zhong, F Zhu, T Kivioja, I Sur, J Lehtiö, ... Nature biotechnology 36 (6), 521-529, 2018 | 35 | 2018 |
| Systematic search for rare variants in Finnish early-onset colorectal cancer patients T Tanskanen, AE Gylfe, R Katainen, M Taipale, L Renkonen-Sinisalo, ... Cancer genetics 208 (1-2), 35-40, 2015 | 32 | 2015 |
| Transcriptional networks controlling the cell cycle M Bonke, M Turunen, M Sokolova, A Vähärautio, T Kivioja, M Taipale, ... G3: Genes| Genomes| Genetics 3 (1), 75-90, 2013 | 32 | 2013 |
| Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion M Sokolova, M Turunen, O Mortusewicz, T Kivioja, P Herr, A Vähärautio, ... Cell cycle 16 (2), 189-199, 2017 | 31 | 2017 |
