Myeloid-derived suppressor cells as a therapeutic target for cancer AMK Law, F Valdes-Mora, D Gallego-Ortega Cells 9 (3), 561, 2020 | 382 | 2020 |
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 257 | 2017 |
Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study AR de Molina, J Sarmentero-Estrada, C Belda-Iniesta, M Tarón, ... The lancet oncology 8 (10), 889-897, 2007 | 183 | 2007 |
The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy AMK Law, E Lim, CJ Ormandy, D Gallego-Ortega Endocrine-related cancer 24 (4), R123, 2017 | 120 | 2017 |
Differential role of human choline kinase α and β enzymes in lipid metabolism: implications in cancer onset and treatment D Gallego-Ortega, A Ramirez de Molina, MA Ramos, F Valdes-Mora, ... PloS one 4 (11), e7819, 2009 | 119 | 2009 |
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ... Development 140 (7), 1397-1401, 2013 | 118 | 2013 |
Droplet-based single cell RNAseq tools: a practical guide R Salomon, D Kaczorowski, F Valdes-Mora, RE Nordon, A Neild, ... Lab on a Chip 19 (10), 1706-1727, 2019 | 111 | 2019 |
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS biology 10 (12), e1001461, 2012 | 104 | 2012 |
TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer F Valdés-Mora, T Gomez del Pulgar, E Bandrés, P Cejas, ... Annals of surgical oncology 16, 78-87, 2009 | 104 | 2009 |
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 103 | 2022 |
Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy AR de Molina, D Gallego-Ortega, J Sarmentero-Estrada, D Lagares, ... The international journal of biochemistry & cell biology 40 (9), 1753-1763, 2008 | 103 | 2008 |
Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway DR Croucher, F Hochgräfe, L Zhang, L Liu, RJ Lyons, D Rickwood, ... Cancer research 73 (6), 1969-1980, 2013 | 102 | 2013 |
Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesis A Ramírez de Molina, D Gallego-Ortega, J Sarmentero, M Bañez-Coronel, ... Cancer research 65 (13), 5647-5653, 2005 | 100 | 2005 |
A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 96 | 2017 |
Regulation of Akt (ser473) phosphorylation by choline kinase in breast carcinoma cells BT Chua, D Gallego-Ortega, AR de Molina, A Ullrich, JC Lacal, ... Molecular Cancer 8, 1-12, 2009 | 89 | 2009 |
Acetylated histone variant H2A. Z is involved in the activation of neo-enhancers in prostate cancer F Valdés-Mora, CM Gould, Y Colino-Sanguino, W Qu, JZ Song, KM Taylor, ... Nature Communications 8 (1), 1346, 2017 | 87 | 2017 |
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib AIJ Young, AMK Law, L Castillo, S Chong, HD Cullen, M Koehler, ... Breast Cancer Research 18, 1-15, 2016 | 87 | 2016 |
Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization JU Mayer, KL Hilligan, JS Chandler, DA Eccles, SI Old, RG Domingues, ... Nature immunology 22 (12), 1538-1550, 2021 | 83 | 2021 |
Single-cell transcriptomics in cancer immunobiology: the future of precision oncology F Valdes-Mora, K Handler, AMK Law, R Salomon, SR Oakes, ... Frontiers in immunology 9, 2582, 2018 | 80 | 2018 |
ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells D Gallego-Ortega, A Ledger, DL Roden, AMK Law, A Magenau, ... PLoS biology 13 (12), e1002330, 2015 | 79 | 2015 |