Natasha Karp
Natasha Karp
Principal Scientist - Statistician, AstraZenea
Verified email at
Cited by
Cited by
Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
S Prabakaran, JE Swatton, MM Ryan, SJ Huffaker, JTJ Huang, JL Griffin, ...
Molecular psychiatry 9 (7), 684, 2004
Circadian orchestration of the hepatic proteome
AB Reddy, NA Karp, ES Maywood, EA Sage, M Deery, JS O'Neill, ...
Current Biology 16 (11), 1107-1115, 2006
Addressing accuracy and precision issues in iTRAQ quantitation
NA Karp, W Huber, PG Sadowski, PD Charles, SV Hester, KS Lilley
Molecular & Cellular Proteomics 9 (9), 1885-1897, 2010
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ...
Cell 154 (2), 452-464, 2013
Glucocorticoid signaling synchronizes the liver circadian transcriptome
AB Reddy, ES Maywood, NA Karp, VM King, Y Inoue, FJ Gonzalez, ...
Hepatology 45 (6), 1478-1488, 2007
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
G Koscielny, G Yaikhom, V Iyer, TF Meehan, H Morgan, J Atienza-Herrero, ...
Nucleic acids research 42 (D1), D802-D809, 2013
Determining a significant change in protein expression with DeCyder™ during a pair‐wise comparison using two‐dimensional difference gel electrophoresis
NA Karp, DP Kreil, KS Lilley
Proteomics 4 (5), 1421-1432, 2004
Maximising sensitivity for detecting changes in protein expression: experimental design using minimal CyDyes
NA Karp, KS Lilley
Proteomics 5 (12), 3105-3115, 2005
Experimental and statistical considerations to avoid false conclusions in proteomics studies using differential in-gel electrophoresis
NA Karp, PS McCormick, MR Russell, KS Lilley
Molecular & Cellular Proteomics 6 (8), 1354-1364, 2007
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium
TF Meehan, N Conte, DB West, JO Jacobsen, J Mason, J Warren, ...
Nature genetics 49 (8), 1231, 2017
Design and analysis issues in quantitative proteomics studies
NA Karp, KS Lilley
Proteomics 7 (S1), 42-50, 2007
Prevalence of sexual dimorphism in mammalian phenotypic traits
NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ...
Nature communications 8, 15475, 2017
Impact of replicate types on proteomic expression analysis
NA Karp, M Spencer, H Lindsay, K O'Dell, KS Lilley
Journal of proteome research 4 (5), 1867-1871, 2005
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
L van der Weyden, MJ Arends, AD Campbell, T Bald, H Wardle-Jones, ...
Nature 541 (7636), 233, 2017
Application of partial least squares discriminant analysis to two‐dimensional difference gel studies in expression proteomics
NA Karp, JL Griffin, KS Lilley
Proteomics 5 (1), 81-90, 2005
Investigating sample pooling strategies for DIGE experiments to address biological variability
NA Karp, KS Lilley
Proteomics 9 (2), 388-397, 2009
Mouse large-scale phenotyping initiatives: Overview of the European mouse disease clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
A Ayadi, MC Birling, J Bottomley, J Bussell, H Fuchs, M Fray, ...
Mammalian genome 23 (9-10), 600-610, 2012
Reproducibility and replicability of rodent phenotyping in preclinical studies
N Kafkafi, J Agassi, EJ Chesler, JC Crabbe, WE Crusio, D Eilam, R Gerlai, ...
Neuroscience & Biobehavioral Reviews 87, 218-232, 2018
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
MH de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ...
Nature genetics 47 (9), 969, 2015
Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock
MJ Deery, ES Maywood, JE Chesham, M Sládek, NA Karp, EW Green, ...
Current Biology 19 (23), 2031-2036, 2009
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