| Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes N Jones, IM Blasutig, V Eremina, JM Ruston, F Bladt, H Li, H Huang, ... Nature 440 (7085), 818-823, 2006 | 568 | 2006 |
| Defining the specificity space of the human SRC homology 2 domain H Huang, L Li, C Wu, D Schibli, K Colwill, S Ma, C Li, P Roy, K Ho, ... Molecular & Cellular Proteomics 7 (4), 768-784, 2008 | 290 | 2008 |
| Superbinder SH2 Domains Act as Antagonists of Cell Signaling T Kaneko, H Huang, X Cao, X Li, C Li, C Voss, SS Sidhu, SSC Li Science Signalling 5 (243), ra68, 2012 | 148 | 2012 |
| Comprehensive analysis of the human SH3 domain family reveals a wide variety of non-canonical specificities J Teyra, H Huang, S Jain, X Guan, A Dong, Y Liu, W Tempel, J Min, ... Structure 25 (10), 1598-1610. e3, 2017 | 138 | 2017 |
| Loops govern SH2 domain specificity by controlling access to binding pockets T Kaneko, H Huang, B Zhao, L Li, H Liu, CK Voss, C Wu, MR Schiller, ... Science signaling 3 (120), ra34-ra34, 2010 | 108 | 2010 |
| The multiple‐specificity landscape of modular peptide recognition domains D Gfeller, F Butty, M Wierzbicka, E Verschueren, P Vanhee, H Huang, ... Molecular systems biology 7 (1), 484, 2011 | 107 | 2011 |
| RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation Z Ni, C Xu, X Guo, GO Hunter, OV Kuznetsova, W Tempel, E Marcon, ... Nature structural & molecular biology 21 (8), 686-695, 2014 | 102 | 2014 |
| Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks M Abu-Odeh, T Bar-Mag, H Huang, TH Kim, Z Salah, SK Abdeen, M Sudol, ... Journal of Biological Chemistry 289 (13), 8865-8880, 2014 | 94 | 2014 |
| Prediction of phosphotyrosine signaling networks using a scoring matrix-assisted ligand identification approach L Li, C Wu, H Huang, K Zhang, J Gan, SSC Li Nucleic acids research 36 (10), 3263-3273, 2008 | 73 | 2008 |
| Interaction Domains of Sos1/Grb2 Are Finely Tuned for Cooperative Control of Embryonic Stem Cell Fate GM Findlay, MJ Smith, F Lanner, MS Hsiung, GD Gish, E Petsalaki, ... Cell 152 (5), 1008-1020, 2013 | 71 | 2013 |
| MUSI: an integrated system for identifying multiple specificity from very large peptide or nucleic acid data sets TH Kim, MS Tyndel, H Huang, SS Sidhu, GD Bader, D Gfeller, PM Kim Nucleic acids research 40 (6), e47-e47, 2012 | 69 | 2012 |
| The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast L Ren, AH Willet, RH Roberts-Galbraith, NA McDonald, A Feoktistova, ... Molecular biology of the cell 26 (2), 256-269, 2015 | 64 | 2015 |
| Advances in Trop2-targeted therapy: Novel agents and opportunities beyond breast cancer X Liu, J Deng, Y Yuan, W Chen, W Sun, Y Wang, H Huang, B Liang, ... Pharmacology & Therapeutics 239, 108296, 2022 | 61 | 2022 |
| A High Efficiency Strategy for Binding Property Characterization of Peptide-binding Domains* S E Song, S Gao, R Tian, S Ma, H Huang, J Guo, Y Li, L Zhang, Y Gao Molecular & Cellular Proteomics 5 (8), 1368-1381, 2006 | 51 | 2006 |
| Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2 H Zhang, K Liu, N Izumi, H Huang, D Ding, Z Ni, SS Sidhu, C Chen, ... Proceedings of the National Academy of Sciences 114 (47), 12483-12488, 2017 | 37 | 2017 |
| Studying binding specificities of peptide recognition modules by high-throughput phage display selections H Huang, SS Sidhu Network Biology: Methods and Applications, 87-97, 2011 | 35 | 2011 |
| Optimizing production of antigens and Fabs in the context of generating recombinant antibodies to human proteins N Zhong, P Loppnau, A Seitova, M Ravichandran, M Fenner, H Jain, ... PloS one 10 (10), e0139695, 2015 | 27 | 2015 |
| Surface Loops in a Single SH2 Domain Are Capable of Encoding the Spectrum of Specificity of the SH2 Family*[S] H Liu, H Huang, C Voss, T Kaneko, WT Qin, S Sidhu, SSC Li Molecular & Cellular Proteomics 18 (2), 372-382, 2019 | 21 | 2019 |
| Allosteric modulation of binding specificity by alternative packing of protein cores M Ben-David, H Huang, MGF Sun, C Corbi-Verge, E Petsalaki, K Liu, ... Journal of molecular biology 431 (2), 336-350, 2019 | 20 | 2019 |
| Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis G Veggiani, H Huang, BP Yates, J Tong, T Kaneko, R Joshi, SSC Li, ... Protein Science 28 (2), 403-413, 2019 | 17 | 2019 |
Shawn Shun-Cheng LiProfessor of Biochemistry, Western University, London, Ontario, CanadaVerified email at uwo.ca
