Small-molecule ligand docking into comparative models with Rosetta SA Combs, SL DeLuca, SH DeLuca, GH Lemmon, DP Nannemann, ... Nature protocols 8 (7), 1277-1298, 2013 | 196 | 2013 |
Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential KJ Gregory, EN Dong, J Meiler, PJ Conn Neuropharmacology 60 (1), 66-81, 2011 | 141 | 2011 |
Probing the metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a “molecular switch” in PAM … KJ Gregory, ED Nguyen, SD Reiff, EF Squire, SR Stauffer, CW Lindsley, ... Molecular pharmacology 83 (5), 991-1006, 2013 | 81 | 2013 |
Identification of specific ligand–receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site KJ Gregory, ED Nguyen, C Malosh, JL Mendenhall, JZ Zic, BS Bates, ... ACS chemical neuroscience 5 (4), 282-295, 2014 | 48 | 2014 |
Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12 P Schmidt, L Ritscher, EN Dong, T Hermsdorf, M Cöster, D Wittkopf, ... Molecular pharmacology 83 (1), 256-266, 2013 | 46 | 2013 |
Assessment and challenges of ligand docking into comparative models of G-protein coupled receptors ED Nguyen, C Norn, TM Frimurer, J Meiler PLoS One 8 (7), e67302, 2013 | 39 | 2013 |
Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket X Pedragosa-Badia, GR Sliwoski, ED Nguyen, D Lindner, J Stichel, ... Journal of Biological Chemistry 289 (9), 5846-5859, 2014 | 37 | 2014 |
Exploration of Allosteric Agonism Structure–Activity Relationships within an Acetylene Series of Metabotropic Glutamate Receptor 5 (mGlu5) Positive Allosteric Modulators … M Turlington, MJ Noetzel, A Chun, Y Zhou, RD Gogliotti, ED Nguyen, ... Journal of medicinal chemistry 56 (20), 7976-7996, 2013 | 34 | 2013 |
BCL:: Align—Sequence alignment and fold recognition with a custom scoring function online E Dong, J Smith, S Heinze, N Alexander, J Meiler Gene 422 (1-2), 41-46, 2008 | 27 | 2008 |
Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells C Lis, S Rubner, M Roatsch, A Berg, T Gilcrest, D Fu, E Nguyen, ... Scientific Reports 7 (1), 17390, 2017 | 23 | 2017 |
Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis DM Okamura, CM Brewer, P Wakenight, N Bahrami, K Bernardi, A Tran, ... Iscience 24 (11), 2021 | 17 | 2021 |
Modeling metabolic variation with single-cell expression data Y Zhang, MS Kim, E Nguyen, DM Taylor bioRxiv, 2020.01. 28.923680, 2020 | 16 | 2020 |
Accurate prediction of contact numbers for multi-spanning helical membrane proteins B Li, J Mendenhall, ED Nguyen, BE Weiner, AW Fischer, J Meiler Journal of chemical information and modeling 56 (2), 423-434, 2016 | 12 | 2016 |
Improving prediction of helix–helix packing in membrane proteins using predicted contact numbers as restraints B Li, J Mendenhall, ED Nguyen, BE Weiner, AW Fischer, J Meiler Proteins: Structure, Function, and Bioinformatics 85 (7), 1212-1221, 2017 | 11 | 2017 |
For whom the bell tolls: Acute kidney injury and electronic alerts for the pediatric nephrologist ED Nguyen, S Menon Frontiers in Pediatrics 9, 628096, 2021 | 5 | 2021 |
Stabilizing long-period orbits in chaotic oscillators with open-source hardware AN Beal, CJ Erickson, ME Alim, ED Nguyen 2020 SoutheastCon, 1-6, 2020 | 3 | 2020 |
Mammalian organ regeneration in spiny mice DM Okamura, ED Nguyen, SJ Collins, K Yoon, JB Gere, ... Journal of Muscle Research and Cell Motility 44 (2), 39-52, 2023 | 2 | 2023 |
Wound healing and regeneration in spiny mice (Acomys cahirinus) DM Okamura, ED Nguyen, DR Beier, MW Majesky Current Topics in Developmental Biology 148, 139-164, 2022 | 2 | 2022 |
Persistence pays off: adult Langerhans cell histiocytosis E Nguyen, D Claar, E McGuinn, K Mast, K Hartley, K McDonagh The American Journal of Medicine 129 (7), e55-e59, 2016 | 2 | 2016 |
ECM-Focused Proteomic Analysis of Ear Punch Regeneration in Acomys Cahirinus MC McCabe, DM Okamura, CB Erickson, BW Perry, CM Brewer, ... bioRxiv, 2023.10. 11.561940, 2023 | 1 | 2023 |