| IL-11 is a crucial determinant of cardiovascular fibrosis S Schafer*, S Viswanathan*, AA Widjaja*, WW Lim, A Moreno-Moral, ... Nature 552 (7683), 110-115, 2017 | 540 | 2017 |
| The translational landscape of the human heart S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ... Cell 178 (1), 242-260. e29, 2019 | 474 | 2019 |
| Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ... Science translational medicine 11 (511), 2019 | 228 | 2019 |
| Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ... Gastroenterology 157 (3), 777-792. e14, 2019 | 221 | 2019 |
| Widespread translational control of fibrosis in the human heart by RNA-binding proteins S Chothani, S Schäfer, E Adami, S Viswanathan, AA Widjaja, SR Langley, ... Circulation 140 (11), 937-951, 2019 | 102 | 2019 |
| Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ... Nature Communications 12 (1), 1-15, 2021 | 90 | 2021 |
| Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation M Tripathi, BK Singh, J Zhou, K Tikno, A Widjaja, R Sandireddy, K Arul, ... Journal of Hepatology 77 (5), 1246-1255, 2022 | 61 | 2022 |
| Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ... Science translational medicine 13 (597), eaba8146, 2021 | 59* | 2021 |
| Wars2 is a determinant of angiogenesis M Wang, P Sips, E Khin, M Rotival, X Sun, R Ahmed, AA Widjaja, ... Nature communications 7 (1), 12061, 2016 | 56 | 2016 |
| A high-resolution map of human RNA translation SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ... Molecular cell 82 (15), 2885-2899. e8, 2022 | 55 | 2022 |
| Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease B Ng, J Dong, S Viswanathan, AA Widjaja, BS Paleja, E Adami, NSJ Ko, ... The FASEB Journal 34 (9), 11802-11815, 2020 | 55 | 2020 |
| Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice WW Lim, B Ng, A Widjaja, C Xie, L Su, N Ko, SY Lim, XY Kwek, S Lim, ... PLoS One 15 (1), e0227505, 2020 | 54 | 2020 |
| Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models WW Lim, B Corden, B Ng, K Vanezis, G D’Agostino, AA Widjaja, WH Song, ... Scientific reports 10 (1), 17853, 2020 | 52 | 2020 |
| Thyroid hormone decreases hepatic steatosis, inflammation, and fibrosis in a dietary mouse model of nonalcoholic steatohepatitis J Zhou, M Tripathi, JP Ho, AA Widjaja, SG Shekeran, MD Camat, A James, ... Thyroid 32 (6), 725-738, 2022 | 44 | 2022 |
| IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts E Adami, S Viswanathan, AA Widjaja, B Ng, S Chothani, N Zhihao, J Tan, ... Rheumatology 60 (12), 5820-5826, 2021 | 39 | 2021 |
| Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy AA Widjaja, SP Chothani, SA Cook Human Vaccines & Immunotherapeutics 16 (10), 2357-2362, 2020 | 39 | 2020 |
| Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression J Zhou, J Pang, M Tripathi, JP Ho, AA Widjaja, SG Shekeran, SA Cook, ... Nature Communications 13 (1), 5202, 2022 | 37 | 2022 |
| Molecular dissection of pro-fibrotic IL11 signaling in cardiac and pulmonary fibroblasts AA Widjaja, S Viswanathan, D Jinrui, BK Singh, J Tan, JG Wei Ting, ... Frontiers in Molecular Biosciences 8, 740650, 2021 | 35 | 2021 |
| IL11 stimulates IL33 expression and proinflammatory fibroblast activation across tissues AA Widjaja, S Chothani, S Viswanathan, JWT Goh, WW Lim, SA Cook International Journal of Molecular Sciences 23 (16), 8900, 2022 | 33 | 2022 |
| Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C‐terminal pentapeptide R Alag, N Bharatham, A Dong, T Hills, A Harikishore, AA Widjaja, ... Protein Science 18 (10), 2115-2124, 2009 | 32 | 2009 |
SIVAKUMAR VISWANATHANPrincipal Research Scientist, Cardiovascular and Metabolic Disorders, Duke-NUS Medical SchoolVerified email at duke-nus.edu.sg
