Anissa Widjaja
Anissa Widjaja
Assistant Professor, Duke-NUS Medical School
Verified email at
Cited by
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IL-11 is a crucial determinant of cardiovascular fibrosis
S Schafer*, S Viswanathan*, AA Widjaja*, WW Lim, A Moreno-Moral, ...
Nature 552 (7683), 110-115, 2017
The translational landscape of the human heart
S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ...
Cell 178 (1), 242-260. e29, 2019
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ...
Science translational medicine 11 (511), 2019
Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis
AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ...
Gastroenterology 157 (3), 777-792. e14, 2019
Widespread translational control of fibrosis in the human heart by RNA-binding proteins
S Chothani, S Schäfer, E Adami, S Viswanathan, AA Widjaja, SR Langley, ...
Circulation 140 (11), 937-951, 2019
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ...
Nature Communications 12 (1), 1-15, 2021
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ...
Science Translational Medicine 13 (597), eaba8146, 2021
Wars2 is a determinant of angiogenesis
M Wang, P Sips, E Khin, M Rotival, X Sun, R Ahmed, AA Widjaja, ...
Nature communications 7 (1), 12061, 2016
Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease
B Ng, J Dong, S Viswanathan, AA Widjaja, BS Paleja, E Adami, NSJ Ko, ...
The FASEB Journal 34 (9), 11802-11815, 2020
Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation
M Tripathi, BK Singh, J Zhou, K Tikno, A Widjaja, R Sandireddy, K Arul, ...
Journal of Hepatology 77 (5), 1246-1255, 2022
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models
WW Lim, B Corden, B Ng, K Vanezis, G D’Agostino, AA Widjaja, WH Song, ...
Scientific reports 10 (1), 17853, 2020
Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
WW Lim, B Ng, A Widjaja, C Xie, L Su, N Ko, SY Lim, XY Kwek, S Lim, ...
PLoS One 15 (1), e0227505, 2020
A high-resolution map of human RNA translation
SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ...
Molecular cell 82 (15), 2885-2899. e8, 2022
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
E Adami, S Viswanathan, AA Widjaja, B Ng, S Chothani, N Zhihao, J Tan, ...
Rheumatology 60 (12), 5820-5826, 2021
Thyroid hormone decreases hepatic steatosis, inflammation, and fibrosis in a dietary mouse model of nonalcoholic steatohepatitis
J Zhou, M Tripathi, JP Ho, AA Widjaja, SG Shekeran, MD Camat, A James, ...
Thyroid 32 (6), 725-738, 2022
Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy
AA Widjaja, SP Chothani, SA Cook
Human Vaccines & Immunotherapeutics 16 (10), 2357-2362, 2020
Molecular dissection of pro-fibrotic IL11 signaling in cardiac and pulmonary fibroblasts
AA Widjaja, S Viswanathan, D Jinrui, BK Singh, J Tan, JG Wei Ting, ...
Frontiers in Molecular Biosciences 8, 740650, 2021
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
J Zhou, J Pang, M Tripathi, JP Ho, AA Widjaja, SG Shekeran, SA Cook, ...
Nature Communications 13 (1), 5202, 2022
Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C‐terminal pentapeptide
R Alag, N Bharatham, A Dong, T Hills, A Harikishore, AA Widjaja, ...
Protein Science 18 (10), 2115-2124, 2009
A neutralizing IL-11 antibody improves renal function and increases lifespan in a mouse model of alport syndrome
AA Widjaja, SG Shekeran, E Adami, JGW Ting, J Tan, S Viswanathan, ...
Journal of the American Society of Nephrology 33 (4), 718-730, 2022
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